Citation Impact
Citing Papers
PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
2013
Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS -Mutant Lung Adenocarcinoma
2015
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis
2008
Cutting Edge: Pivotal Function of Ubc13 in Thymocyte TCR Signaling
2006
Pirk Is a Negative Regulator of the Drosophila Imd Pathway
2008
Streptococcus pneumoniae stabilizes tumor necrosis factor α mRNA through a pathway dependent on p38 MAPK but independent of Toll-like receptors
2008
The N-terminal Domain of Drosophila Gram-negative Binding Protein 3 (GNBP3) Defines a Novel Family of Fungal Pattern Recognition Receptors
2009 StandoutNobel
TAK1 Is a Central Mediator of NOD2 Signaling in Epidermal Cells
2007
RNAi screening comes of age: improved techniques and complementary approaches
2014
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
2006
TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β
2008
Ubiquitin-mediated activation of TAK1 and IKK
2007
A view on drug resistance in cancer
2019 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme
2008
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMO
2006
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Cell type-specific function of TAK1 in innate immune signaling
2013
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
2006
Genetic analysis of resistance to viral infection
2007 StandoutNobel
Crosstalk of reactive oxygen species and NF-κB signaling
2010 Standout
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
IAP-targeted therapies for cancer
2008
Shared Principles in NF-κB Signaling
2008 Standout
Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer
2006
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing
2007
Opportunities and challenges in phenotypic drug discovery: an industry perspective
2017
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice
2007 StandoutNobel
Mammalian microRNAs predominantly act to decrease target mRNA levels
2010 StandoutNature
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Reactive Oxygen Species in TNFα-Induced Signaling and Cell Death
2010
Intracellular Toll-like Receptors
2010 StandoutNobel
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
The Drosophila Inhibitor of Apoptosis (IAP) DIAP2 Is Dispensable for Cell Survival, Required for the Innate Immune Response to Gram-negative Bacterial Infection, and Can Be Negatively Regulated by the Reaper/Hid/Grim Family of IAP-binding Apoptosis Inducers
2006
Toll-Like Receptors in Alzheimer's Disease
2009
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
NF-κB and the immune response
2006
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
2013
TAK1 Is a Master Regulator of Epidermal Homeostasis Involving Skin Inflammation and Apoptosis
2006
TAK1 Negatively Regulates NF-κB and p38 MAP Kinase Activation in Gr-1+CD11b+ Neutrophils
2012
Non-Smad pathways in TGF-β signaling
2008
Origin, Biogenesis, and Activity of Plant MicroRNAs
2009 Standout
Mechanisms of resistance to therapies targeting BRCA-mutant cancers
2013
Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation
2006
Mechanisms of crosstalk between TNF-induced NF-κB and JNK activation in hepatocytes
2006
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
TGFβ in Cancer
2008 Standout
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
A critical role of RICK/RIP2 polyubiquitination in Nod‐induced NF‐κB activation
2007
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
2007 StandoutNobel
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Function of Nod‐like receptors in microbial recognition and host defense
2008
IκB kinase complexes: gateways to NF-κB activation and transcription
2006
Synthetic lethal therapies for cancer: what’s next after PARP inhibitors?
2018
The PI3K Pathway in Human Disease
2017 Standout
Drugging the undruggable RAS: Mission Possible?
2014
Reactive oxygen species, cellular redox systems, and apoptosis
2010 Standout
TRIM family proteins and their emerging roles in innate immunity
2008
NF- B in the Immune Response of Drosophila
2009 StandoutNobel
Toll-Like Receptor Signaling Pathways
2014 Standout
Cooperative control of Drosophila immune responses by the JNK and NF‐κB signaling pathways
2006
Generation and testing of clinical-grade exosomes for pancreatic cancer
2018
Positive and negative regulation of the Drosophila immune response
2008
Signaling to NF-κB by Toll-like receptors
2007 Standout
Recognition and Signaling by Toll-Like Receptors
2006
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of IκBα Kinase
2008
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
Improving Prospects for Targeting RAS
2015
The TGFβ activated kinase TAK1 regulates vascular development in vivo
2006
Structure and Function of Toll Receptors and Their Ligands
2007
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
2007 StandoutNobel
Identification of Drosophila Mutants Altering Defense of and Endurance to Listeria monocytogenes Infection
2008
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
The Role of Ubiquitin in NF-κB Regulatory Pathways
2009
Sensing of Viral Infection and Activation of Innate Immunity by Toll-Like Receptor 3
2008
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
2007
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Essential Roles of K63-Linked Polyubiquitin-Binding Proteins TAB2 and TAB3 in B Cell Activation via MAPKs
2013
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
TLRs and innate immunity
2008 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
The Drosophila Inhibitor of Apoptosis Protein DIAP2 Functions in Innate Immunity and Is Essential To Resist Gram-Negative Bacterial Infection
2006
Genomic Screening with RNAi: Results and Challenges
2010
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Regulation and Function of IKK and IKK-Related Kinases
2006
Essential role of TAK1 in thymocyte development and activation
2006
KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment
2016
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
2007 StandoutNobel
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
2009 StandoutNobel
Constitutive ALK5-Independent c-Jun N-Terminal Kinase Activation Contributes to Endothelin-1 Overexpression in Pulmonary Fibrosis: Evidence of an Autocrine Endothelin Loop Operating through the Endothelin A and B Receptors
2006
Works of Michael Steckel being referenced
An RNA interference screen ide.jpgies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila
2005
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
2005
Functional Genomics in Pharmaceutical Drug Discovery
2015
Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies
2012
The GATA2 Transcriptional Network Is Requisite for RAS Oncogene-Driven Non-Small Cell Lung Cancer
2012