Citation Impact
Citing Papers
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
2007 Standout
The role of bile acids in functional GI disorders
2014
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
An update on the regulatory mechanisms of NLRP3 inflammasome activation
2021
Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
2013 Standout
Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon
2017 Standout
Gut microbiota, inflammation and colorectal cancer
2016
Engineering precision nanoparticles for drug delivery
2020 Standout
Autophagy as a promoter of longevity: insights from model organisms
2018
PTPN22: the archetypal non-HLA autoimmunity gene
2014
Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease
2006
External Influence of Early Childhood Establishment of Gut Microbiota and Subsequent Health Implications
2014
Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity
2010
Genetic Variations of PTPN2 and PTPN22: Role in the Pathogenesis of Type 1 Diabetes and Crohn's Disease
2015
Bowel Functions, Fecal Unconjugated Primary and Secondary Bile Acids, and Colonic Transit in Patients With Irritable Bowel Syndrome
2013
Biosynthetic capacity, metabolic variety and unusual biology in the CPR and DPANN radiations
2018
Microbial tryptophan catabolites in health and disease
2018 Standout
Ulcerative Colitis
2011 Standout
Chronic inflammation in the etiology of disease across the life span
2019 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Hallmarks of aging: An expanding universe
2023 Standout
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
2019
The effects of vitamin A supplementation with measles vaccine on leucocyte counts andin vitrocytokine production
2015
IL-13 Promotes Collagen Accumulation in Crohn’s Disease Fibrosis by Down-Regulation of Fibroblast MMP Synthesis: A Role for Innate Lymphoid Cells?
2012
Crohn's disease
2012 Standout
Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial
2016
The respiratory microbiome: an underappreciated player in the human response to inhaled pollutants?
2016
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Epidemiology and risk factors for IBD
2015 Standout
Inflammatory Bowel Disease
2009 Standout
Genetics of Inflammatory Bowel Diseases
2015
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Protein tyrosine phosphatase non-receptor type 2 and inflammatory bowel disease
2016
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Metagenomic biomarker discovery and explanation
2011 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Obesity in autoimmune diseases: Not a passive bystander
2014
Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
2016
Crohn's disease
2016 Standout
Hygiene and other early childhood influences on the subsequent function of the immune system
2014
Intestinal mucosal barrier function in health and disease
2009 Standout
Remodelling the extracellular matrix in development and disease
2014 Standout
Periodontitis: from microbial immune subversion to systemic inflammation
2014 Standout
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
New genes in inflammatory bowel disease: lessons for complex diseases?
2006
Periodontal disease and subgingival microbiota as contributors for rheumatoid arthritis pathogenesis
2014
Collective cell migration in morphogenesis, regeneration and cancer
2009 Standout
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
2008 Standout
Ulcerative colitis
2016 Standout
Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation
2016
PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis
2020 StandoutNobel
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Advances in IBD genetics
2014
Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
2013 Standout
Transforming Growth Factor-β, a Whey Protein Component, Strengthens the Intestinal Barrier by Upregulating Claudin-4 in HT-29/B6 Cells1,2
2011
Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2
2012
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Gut microbiota, metabolites and host immunity
2016 Standout
Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies
2017 Standout
Ephrin-B2 is differentially expressed in the intestinal epithelium in Crohn’s disease and contributes to accelerated epithelial wound healingin vitro
2005
Sex differences in immune responses
2016 Standout
Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation
2017
Biologic agents for IBD: practical insights
2015
Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation
2011
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
The Clustering of Other Chronic Inflammatory Diseases in Inflammatory Bowel Disease: A Population-Based Study
2005
Occludin Protein Family: Oxidative Stress and Reducing Conditions
2011
Irritable Bowel Syndrome
2015 Standout
Clinical Aspects and Pathophysiology of Inflammatory Bowel Disease
2002
Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits
2017 Standout
Regulatory T Cells and Human Disease
2020 StandoutNobel
Tyrosine Phosphatase PTPN22: Multifunctional Regulator of Immune Signaling, Development, and Disease
2013
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
2019
Prevalence of inflammatory bowel disease: estimates for 2010 and trends in Germany from a large insurance-based regional cohort
2014
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
2016 StandoutNobel
Introduction to the human gut microbiota
2017 Standout
European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis
2008
Spermidine in health and disease
2018 StandoutScience
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility
2006
European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies
2015
Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease
2018
Plastic and Human Health: A Micro Issue?
2017 Standout
Claudins and the Modulation of Tight Junction Permeability
2013 Standout
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Four types of B ifidobacteria trigger autophagy response in intestinal epithelial cells
2014
Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling
2015
Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis
2020 StandoutNobel
Works of Michael Scharl being referenced
AMP-activated Protein Kinase Mediates the Interferon-γ-induced Decrease in Intestinal Epithelial Barrier Function
2009
Protein Tyrosine Phosphatase Non-Receptor Type 22 Modulates NOD2-Induced Cytokine Release and Autophagy
2013
Smoking Cessation Alters Intestinal Microbiota
2014
PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer
2018
Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2
2009
Epithelial-to-mesenchymal transition in a fistula-associated anal adenocarcinoma in a patient with long-standing Crohn’s disease
2013
Activation of Protein Tyrosine Phosphatase Non-Receptor Type 2 by Spermidine Exerts Anti-Inflammatory Effects in Human THP-1 Monocytes and in a Mouse Model of Acute Colitis
2013
Protein Tyrosine Phosphatase Nonreceptor Type 2 Regulates Autophagosome Formation in Human Intestinal Cells
2011
PTPN2 controls differentiation of CD4+ T cells and limits intestinal inflammation and intestinal dysbiosis
2014
Protein tyrosine phosphatase N2 regulates TNFα-induced signalling and cytokine secretion in human intestinal epithelial cells
2010
Crohn's Disease: Loss of Tolerance or a Disorder of Autophagy?
2014
Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: structure-activity relationships
2006
A Cell Type-Specific Role of Protein Tyrosine Phosphatase Non-Receptor Type 2 in Regulating ER Stress Signalling
2015
Protein Tyrosine Phosphatase non-Receptor Type 2 regulates IFN-γ-induced cytokine signaling in THP-1 monocytes
2010
Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes
2004
The effects of vitamin A on cells of innate immunity in vitro
2013
Inflammatory Bowel Disease: Dysfunction of Autophagy?
2012
The role for protein tyrosine phosphatase nonreceptor type 2 in regulating autophagosome formation
2012
Bilberry-Derived Anthocyanins Prevent IFN-γ-Induced Pro-Inflammatory Signalling and Cytokine Secretion in Human THP-1 Monocytic Cells
2014
Pathophysiology of fistula formation in Crohn's disease
2014
Inflammatory bowel disease pathogenesis
2012
Loss of Protein Tyrosine Phosphatase Nonreceptor Type 22 Regulates Interferon-γ–Induced Signaling in Human Monocytes
2013
Systematic Assessment of Factors Influencing Preferences of Crohnʼs Disease Patients in Selecting an Anti-Tumor Necrosis Factor Agent (CHOOSE TNF TRIAL)
2011
Deficiency of Protein Tyrosine Phosphatase Non-Receptor Type 2 in Intestinal Epithelial Cells Has No Appreciable Impact on Dextran Sulphate Sodium Colitis Severity But Promotes Wound Healing
2016
Crohnʼs disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy
2011
Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome
2016
Smoking Cessation Induces Profound Changes in the Composition of the Intestinal Microbiota in Humans
2013
Interleukin-13 and transforming growth factor β synergise in the pathogenesis of human intestinal fistulae
2012
Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease
2013
Extraintestinal Manifestations of Inflammatory Bowel Disease
2015
Loss of protein tyrosine phosphatase N2 potentiates epidermal growth factor suppression of intestinal epithelial chloride secretion
2010
PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner
2017
Protein Tyrosine Phosphatase Nonreceptor Type 2: An Important Regulator of lnterleukin‐6 Production in Rheumatoid Arthritis Synovial Fibroblasts
2015
Apical leptin induces chloride secretion by intestinal epithelial cells and in a rat model of acute chemotherapy-induced colitis
2010
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
2016