Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
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A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
2010 StandoutScience
Targeted cell killing by reconstituted caspases
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Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume
2002
Characterization of the single‐channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord
2001
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
1997
Glutamate receptor ion channels
2005 Standout
Synapses and Alzheimer's Disease
2012 StandoutNobel
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Pharmacological Characterization of Ro 63-1908 (1-[2-(4-Hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a Novel Subtype-Selective N-Methyl-d-Aspartate Antagonist
2002
Apoptosis in the nervous system
2000 StandoutNature
Gene knockdown with intrathecal siRNA of NMDA receptor NR2B subunit reduces formalin-induced nociception in the rat
2004
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
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A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Calpain and caspase: can you tell the difference?
2000 Standout
Traumatic brain injury and Alzheimer's disease: a review
2007
The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors
2002
The role of substance P in stress and anxiety responses
2006
In situ assembly of enzyme inhibitors using extended tethering
2003
Discovery of (−)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1H)-quinolinone—A potent NR2B-selective N-methyl d-aspartate (NMDA) antagonist for the treatment of pain
2007
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
FTY720 modulates human oligodendrocyte progenitor process extension and survival
2007
Cytochrome c Deficiency Causes Embryonic Lethality and Attenuates Stress-Induced Apoptosis
2000
The amyloid precursor protein (APP)‐cytoplasmic fragment generated by γ‐secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture
2001
Chapter 28 The glutamate synapse in neuropsychiatric disorders: Focus on schizophrenia and Alzheimer's disease
1998
Allosteric modulators of NR2B‐containing NMDA receptors: molecular mechanisms and therapeutic potential
2009
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-d-aspartate receptors
2009
Tyrosine Phosphorylation of the β-Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc
2002
The biochemistry of apoptosis
2000 StandoutNature
Mitochondria: In Sickness and in Health
2012 Standout
Cellular and behavioural profile of the novel, selective neurokinin1 receptor antagonist, vestipitant: A comparison to other agents
2008
Caspase-3 Is Enriched in Postsynaptic Densities and Increased in Alzheimer's Disease
2008
Ghrelin induces adiposity in rodents
2000 StandoutNature
Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists
2003
Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation
2004 StandoutNobel
Neuron–glia crosstalk gets serious: role in pain hypersensitivity
2008
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
2010
Caspase structure, proteolytic substrates, and function during apoptotic cell death
1999
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
2001
A role for ghrelin in the central regulation of feeding
2001 StandoutNature
In vitro and antinociceptive profile of HON0001, an orally active NMDA receptor NR2B subunit antagonist
2006
Regulation of apoptosis by endoplasmic reticulum pathways
2003
NMDA receptor antagonists as analgesics: focus on the NR2B subtype
2001
A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor
2000
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein
2010
Glutamate-based therapeutic approaches: NR2B receptor antagonists
2005
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
2000
Induction of ΔFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses
2007
Targeting the NMDA Receptor Subunit NR2B for the Treatment of Neuropathic Pain
2009
Neuroprotection in the PNS: Erythropoietin and Immunophilin Ligands
2005
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Down‐regulation of amygdala preprotachykinin A mRNA but not3H‐SP receptor binding sites in subjects affected by mood disorders and schizophrenia
2005
Oxamides as novel NR2B selective NMDA receptor antagonists
2004
Catalytic Asymmetric Torgov Cyclization: A Concise Total Synthesis of (+)‐Estrone
2014 StandoutNobel
Kinetic Resolution of Secondary Alcohols Catalyzed by Chiral Phosphoric Acids
2013
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain
2008
The molecular neurobiology of depression
2008 StandoutNature
Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi
2004
Activation of Caspase-3 in Single Neurons and Autophagic Granules of Granulovacuolar Degeneration in Alzheimer's Disease
1999
NMDA receptor pathways as drug targets
2002
Selective Neuronal Degeneration in Huntington's Disease
2006
Fyn kinase‐mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain
2005
The β‐Amyloid Precursor Protein (APP) and Alzheimer's Disease: Does the Tail Wag the Dog?
2002
A decade of caspases
2003
Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
The Role of N-Methyl-d-Aspartate (NMDA) Receptors in Pain: A Review
2003
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat
1997
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*
1998 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Role of Distinct NMDA Receptor Subtypes at Central Synapses
2004
Dextromethorphan and Memantine in Painful Diabetic Neuropathy and Postherpetic Neuralgia
2002
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
In Situ Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications
2004 StandoutNobel
A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing
2002
NR2B subtype-selective NMDA receptor antagonists: 2001 – 2004
2005
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization.
1997
In Situ Selection of Lead Compounds by Click Chemistry: Target-Guided Optimization of Acetylcholinesterase Inhibitors
2005 StandoutNobel
Enantiomeric Propanolamines as selectiveN-Methyl-d -aspartate 2B Receptor Antagonists
2008
Caspase activity sows the seeds of neuronal death
1999
The Prokineticins: Neuromodulators and Mediators of Inflammation and Myeloid Cell-Dependent Angiogenesis
2018
Nitrated Confined Imidodiphosphates Enable a Catalytic Asymmetric Oxa-Pictet–Spengler Reaction
2016 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Apoptosis in Neural Development and Disease
2000
APL-1, a Caenorhabditis elegans protein related to the human β-amyloid precursor protein, is essential for viability
2007
Peptidomimetic Regulation of Growth Hormone Secretion
1997
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Kinetic Resolution of Secondary Alcohols Catalyzed by Chiral Phosphoric Acids
2013
Cross-Talk between Two Cysteine Protease Families
2000 Standout
Caspase-2 Mediates Neuronal Cell Death Induced by β-Amyloid
2000
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
2000 StandoutNobel
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
Works of Michael Rigby being referenced
The messenger RNAs for the N-methyl- d-aspartate receptor subunits show region-specific expression of different subunit composition in the human brain
1996
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn
1999
L-733,060, a novel tachykinin NK1 receptor antagonist; effects in [Ca2+]i mobilisation, cardiovascular and dural extravasation assays
1996
Lack of effect of L‐687,414 ((+)‐cis‐4‐methyl‐HA‐966)5 an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology
1993
Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation
1999
Intra-amygdala injection of the substance P (NK1 receptor) antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs
2001
EDG Receptors as a Therapeutic Target in the Nervous System
2000
Analysis of the neurotrophic effects of GPI-1046 on neuron survival and regeneration in culture and in vivo
1999
Competitive as well as uncompetitive N-methyl-D-aspartate receptor antagonists affect cortical neuronal morphology and cerebral glucose metabolism
1993
Induction of c-fos mRNA in the arcuate nucleus of normal and mutant growth hormone-deficient mice by a synthetic non-peptidyl growth hormone secretagogue
1995
The ultrastructural localisation of the N-methyl-d-aspartate NR2B receptor subunit in rat lumbar spinal cord
2004
Substance P (Neurokinin 1) Receptor Antagonists Enhance Dorsal Raphe Neuronal Activity
2002