Citation Impact
Citing Papers
Role of UEV-1, an Inactive Variant of the E2 UbiquitinConjugating Enzymes, in In Vitro Differentiation and Cell Cycle Behavior of HT-29-M6 Intestinal Mucosecretory Cells
1998 StandoutNobel
In vitro and In vivo Radiosensitization with AZD6244 (ARRY-142886), an Inhibitor of Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase 1/2 Kinase
2009
mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt
2006 Standout
A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells
2001
Treatment of kidney cancer
2009 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts.
2002
Acromegaly
2006 Standout
Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes
1988 StandoutNature
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Smad transcription factors
2005 Standout
DNA Damage and Repair
1991
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
Head and neck cancer
2008 Standout
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
2003
When Checkpoints Fail
1997 StandoutNobel
HSP90 and the chaperoning of cancer
2005 Standout
Neurogenesis in the adult human hippocampus
1998 Standout
Involvement of Brca2 in DNA Repair
1998 StandoutNobel
Low Doses of UVB or UVA Induce Chromosomal Aberrations in Cultured Human Skin Cells
2000
The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
2005
Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway
2003
Lack of recovery from oxygen-induced damage to colony formation and DNA synthesis in senescent human diploid fibroblasts
1987
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
1999 Standout
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase
1989 StandoutNobel
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Systemic Lupus Erythematosus
2011 Standout
DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139
1998 Standout
Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population
1989
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Molecular themes in oncogenesis
1991 StandoutNobel
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Reparability of DNA Double-strand Breaks and Radiation Sensitivity in Five Mammalian Cell Lines
1991
Stem Cells and Cancer
2004 Standout
Pancreatic Cancer
2010 Standout
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
2008 Standout
Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study
2011 Standout
The PI3K Pathway in Human Disease
2017 Standout
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
1990
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway
2000
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
The spindle-assembly checkpoint in space and time
2007 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part I: Historical perspectives, histochemical methods and cell kinetics
1995
Mad2 transiently associates with an APC/p55Cdc complex during mitosis
1998
TGF-β SIGNAL TRANSDUCTION
1998 Standout
Altered phosphorylation and activation of PP60c-src during fibroblast mitosis
1988
Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo
1999 Standout
The Free Radical Theory of Aging Matures
1998 Standout
Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
2008 Standout
Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and tumor biology matters, Clin. Cancer Res., 7: 2155-2158, 2001.
2001
Differential Phosphorylation of the Transcription Factor Oct1 During the Cell Cycle
1991 Science
Long-Distance Neuronal Migration in the Adult Mammalian Brain
1994 StandoutScience
Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part I: Historical perspectives, histochemical methods and cell kinetics
1995
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15
1997 Nature
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation
2000
Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics
2002 Standout
Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor
2004 StandoutScience
The lamin B receptor of the inner nuclear membrane undergoes mitosis-specific phosphorylation and is a substrate for p34cdc2-type protein kinase.
1992 StandoutNobel
Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells
2001 Standout
The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle.
1994
Cell-Cycle-Dependent Repair of Potentially Lethal Damage in the XR-1 γ-Ray-Sensitive Chinese Hamster Ovary Cell
1988
Polycomb Group Gene rae28 Is Required for Sustaining Activity of Hematopoietic Stem Cells
2002
Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells.
1995
A novel pyridopyrimidine inhibitor of abl kinase is a picomolar inhibitor of Bcr-abl-driven K562 cells and is effective against STI571-resistant Bcr-abl mutants.
2003
Maturation-promoting factor and the regulation of the cell cycle
1989 StandoutNobel
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
DNA Double-Strand Breaks
2002 StandoutNobel
Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know
2003 Standout
Induction and persistence of cytogenetic damage in mouse splenocytes following whole-body X-irradiation analysed by fluorescence in situ hybridization. II. Micronuclei
1996
Smoking and Smokeless Tobacco-Associated Human Buccal Cell Mutations and Their Association with Oral Cancer—A Review
2006
Evidence for DNA-PK-Dependent and -Independent DNA Double-Strand Break Repair Pathways in Mammalian Cells as a Function of the Cell Cycle
1997
Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4
1998 StandoutNobel
Thyroid carcinoma
2003 Standout
Radiation-Induced Adaptive Response for Protection against Micronucleus Formation and Neoplastic Transformation in C3H 10T1/2 Mouse Embryo Cells
1994
Works of Michael Nüsse being referenced
Flow cytometric analysis of G1‐ and G2/M‐phase subpopulations in mammalian cell nuclei using side scatter and DNA content measurements
1990
Flow cytometric analysis of micronuclei in cell cultures and human lymphocytes: advantages and disadvantages
1997
Micronuclei: a biological indicator of radiation damage
1996
Flow cytometric detection of mitotic cells using the bromodeoxyuridine/DNA technique in combination with 90° and forward scatter measurements
1989
A New method to discriminate G1, S, G2, M, and G1 postmitotic cells
1989
Analysis of radiation-induced micronuclei by FISH using a combination of painting and centromeric DNA probes
1997
Multiparametric flow cytometric analysis of radiation‐induced micronuclei in mammalian cell cultures
1992
Flow cytometric detection of micronuclei by combined staining of DNA and membranes
1995
Chapter 9 Measurement of Micronuclei by Flow Cytometry
1994
Analysis of micronuclei induced by 2-chlorobenzylidene malonitrile (CS) using fluorescence in situ hybridization with telomeric and centromeric DNA probes, and flow cytometry
1993
Kinetics of Double Strand Break Repair in the DNA of X-irradiated Synchronized Mammalian Cells
1983
Conditions Supporting Repair of Potentially Lethal Damage Cause a Significant Reduction of Ultraviolet Light-Induced Division Delay in Synchronized and Plateau-Phase Ehrlich Ascites Tumor Cells
1982
Cell cycle kinetic measurements in an irradiated rat rhabdomyosarcoma using a monoclonal antibody to bromodeoxyuridine
1985
Analysis of Radiation-Induced Micronuclei by Fluorescence In Situ Hybridization (FISH) Simultaneously Using Telomeric and Centromeric DNA Probes
1992
Arrest of Irradiated G1, S, or G2 Cells at Mitosis Using Nocodazole Promotes Repair of Potentially Lethal Damage
1984
Chapter 25 Light Scatter of Isolated Cell Nuclei as a Parameter Discriminating the Cell-Cycle Subcompartments
1994
Effects of Caffeine on X-irradiated Synchronous, Asynchronous and Plateau Phase Mouse Ascites Cells: The Importance of Progression Through the Cell Cycle for Caffeine Enhancement of Killing
1983
Can Nocodazole, an Inhibitor of Microtubule Formation, Be Used to Synchronize Mammalian Cells?
1984
Conditions supporting repair of potentially lethal damage cause a significant reduction of ultraviolet light-induced division delay in synchronized and plateau-phase Ehrlich ascites tumor cells.
1982
Evidence That Repair and Expression of Potentially Lethal Damage Cause the Variations in Cell Survival after X Irradiation Observed through the Cell Cycle in Ehrlich Ascites Tumor Cells
1983