Standout Papers
- Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG (2016)
- Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets (2016)
- Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization (2014)
- Effect of Different Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins (2019)
- Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine (2018)
- No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue Syndrome (2011)
- Superior immunogenicity of HCV envelope glycoproteins when adjuvanted with cyclic-di-AMP, a STING activator or archaeosomes (2017)
- Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus (2017)
- A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1 (2019)
Citation Impact
Citing Papers
Structure-Based Design of Hepatitis C Virus E2 Glycoprotein Improves Serum Binding and Cross-Neutralization
2020
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Human Eosinophils Recognize Endogenous Danger Signal Crystalline Uric Acid and Produce Proinflammatory Cytokines Mediated by Autocrine ATP
2010
ICOS Coreceptor Signaling Inactivates the Transcription Factor FOXO1 to Promote Tfh Cell Differentiation
2015
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
2018 StandoutNobel
Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
2014 Nature
Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome
2015 StandoutNobel
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells
2015
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Lysosomes: fusion and function
2007 Standout
Tranexamic Acid Radically Decreases Blood Loss and Transfusions Associated with Total Knee Arthroplasty
1997
CCL5 evokes calcium signals in microglia through a kinase‐, phosphoinositide‐, and nucleotide‐dependent mechanism
2006
Nucleotide signalling during inflammation
2014 StandoutNature
Aprotinin Reduces Blood Loss in Patients Undergoing Elective Liver Resection
1997
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Aprotinin reduces blood loss and the need for transfusionin orthognathic surgery
2001
Molecular programming of B cell memory
2011
Regional Hemostatic Status and Blood Requirements After Total Knee Arthroplasty With and Without Tranexamic Acid or Aprotinin
2001
Designing an HCV vaccine: a unique convergence of prevention and therapy?
2017
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
2010 Standout
Aprotinin Decreases Blood Loss and Homologous Transfusions in Patients Undergoing Major Orthopedic Surgery
1998
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Shedding light on the cell biology of extracellular vesicles
2018 Standout
The development of allergic inflammation
2008 StandoutNature
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
2011 Standout
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4
2014 StandoutNobel
The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control
2016
Local PIP2 signals: when, where, and how?
2007
Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4
2013
Myosin V Transports Secretory Vesicles via a Rab GTPase Cascade and Interaction with the Exocyst Complex
2011 StandoutNobel
Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
2017
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Hepatitis C Virus E2 Envelope Glycoprotein Induces an Immunoregulatory Phenotype in Macrophages
2018
The efficacy of single-dose aprotinin 2 million KIU in reducing blood loss and its impact on the incidence of deep venous thrombosis in patients undergoing total hip replacement surgery
1996
Hepatitis C Virus: 30 Years after Its Discovery
2019 StandoutNobel
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Challenges and Promise of a Hepatitis C Virus Vaccine
2019
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
1999
The PI3K Pathway in Human Disease
2017 Standout
Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
2014 Standout
Regulation of Immunoglobulin Class-Switch Recombination
2014
Exploring the full spectrum of macrophage activation
2008 Standout
Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus
2019 StandoutNobel
Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
2022
Expression of the Longin domain of TI‐VAMP impairs lysosomal secretion and epithelial cell migration
2007
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
2011
Recent insights into the mucosal reactions associated with Giardia lamblia infections
2005
The core domain of hepatitis C virus glycoprotein E2 generates potent cross‐neutralizing antibodies in guinea pigs
2016
Mast cell and eosinophil surface receptors as targets for anti-allergic therapy
2016
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
2017 Standout
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
Regional Hemostatic Status and Blood Requirements After Total Knee Arthroplasty With and Without Tranexamic Acid or Aprotinin
2001
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
2016 Standout
Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge
2015
Regulatory T Cells and Human Disease
2020 StandoutNobel
Follicular Helper CD4 T Cells (TFH)
2011 Standout
Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation
2019 StandoutNobel
Aprotinin Reduces Blood Loss in Patients Undergoing Elective Liver Resection
1997
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
2011 Standout
The origins, function, and regulation of T follicular helper cells
2012
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
Complex heatmaps reveal patterns and correlations in multidimensional genomic data
2016 Standout
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances
2005
Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway
2005
Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity
2016
Tranexamic Acid Radically Decreases Blood Loss and Transfusions Associated with Total Knee Arthroplasty
1997
Prevention of hepatitis C virus infection using a broad cross‐neutralizing monoclonal antibody (AR4A) and epigallocatechin gallate
2015 StandoutNobel
Follicular Helper T Cells
2016
IRF4 at the crossroads of effector T‐cell fate decision
2014
Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model
2017 StandoutNobel
Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells
2019 StandoutNobel
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
2010 Standout
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment
2017 StandoutNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Th9 cell development requires a BATF-regulated transcriptional network
2013
Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response
2022 StandoutNobel
Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations
2019
Physiology of Microglia
2011 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Michael Logan being referenced
Fusion protein vesicle-associated membrane protein 2 is implicated in IFN-γ–induced piecemeal degranulation in human eosinophils from atopic individuals
2001
Use of aprotinin in knee replacement surgery
1994
Regulation of the actin cytoskeleton by PIP2 in cytokinesis
2006
A critical role for vesicle‐associated membrane protein‐7 in exocytosis from human eosinophils and neutrophils
2006
No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue Syndrome
2011 StandoutNobel
Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets
2016 StandoutNobel
Jejunal Brush Border Microvillous Alterations inGiardia muris-Infected Mice: Role of T Lymphocytes and Interleukin-6
2000
Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization
2014 StandoutNobel
Myosin-driven peroxisome partitioning inS. cerevisiae
2009
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
2019 StandoutNobel
Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
2017 StandoutNobel
Batf coordinates multiple aspects of B and T cell function required for normal antibody responses
2010
Understanding exocytosis in immune and inflammatory cells: The molecular basis of mediator secretion
2003
Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG
2016 StandoutNobel
Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
2018 StandoutNobel