Citation Impact
Citing Papers
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
DDI2 Is a Ubiquitin-Directed Endoprotease Responsible for Cleavage of Transcription Factor NRF1
2020
HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity
2009
Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen
1997 Standout
Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: Multicolumn peptide synthesis of enzyme substrates for subtilisin carlsberg and pepsin
1991 StandoutNobel
[6] Synthetic approaches to continuous assays of retroviral proteases
1994
Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virus
1992
Structural and biochemical studies of retroviral proteases
2000
PDB-based protein loop prediction: parameters for selection and methods for optimization
1997 StandoutNobel
A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of .gamma.-turn mimetics into a model substrate
1993
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays
1992
Peptidomimetics derived from natural products
1993
Asymmetric Catalysis by Chiral Hydrogen‐Bond Donors
2006 Standout
Thermodynamic linkage between the binding of protons and inhibitors to HIV‐1 protease
1999
Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy
1997 Standout
Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer
1996 StandoutNobel
Assessment of protein models with three-dimensional profiles
1992 StandoutNature
Recent Developments in Inhibiting Cysteine and Serine Proteases
1990
HIV as the cause of AIDS
1996 StandoutNobel
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
The importance of extended conformations and, in particular, the PII conformation for the molecular recognition of peptides
1995
Structure at 2.5-.ANG. resolution of chemically synthesized Human Immunodeficiency Virus Type 1 protease complexed with a hydroxyethylene-based inhibitor
1991
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
1999 StandoutNature
In the Golden Age of Organocatalysis
2004 Standout
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
1999 StandoutNature
Design, Activity, and 2.8 Å Crystal Structure of a C 2 Symmetric Inhibitor Complexed to HIV-1 Protease
1990 Science
Rational Design of Peptide-Based HIV Proteinase Inhibitors
1990 Science
Fluorine in medicinal chemistry
2007 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
A Substrate-Based Difluoro Ketone Selectively Inhibits Alzheimer's γ-Secretase Activity
1998
A Theoretical Investigation of Phosphonamidates and Sulfonamides as Protease Transition State Isosteres
1998
Anti-retroviral therapy of human immunodeficiency virus infection: current strategies and challenges for the future [published erratum appears in Blood 1991 Dec 15;78(12):3330]
1991
HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and Therapy
1995 StandoutScience
Molecular Targets for AIDS Therapy
1990 Science
Peptidomimetics—Tailored Enzyme Inhibitors
1994
Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems
1993 Standout
A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro
1995 StandoutNobel
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
Asymmetrische Katalyse mit Hetero‐Dimetall‐Verbindungen
1997
THE GREEN FLUORESCENT PROTEIN
1998 StandoutNobel
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
Flavivirus enzyme-substrate interactions studied with chimeric proteinases: identification of an intragenic locus important for substrate recognition
1991
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Extensive comparison of the substrate preferences of two subtilisins as determined with peptide substrates which are based on the principle of intramolecular quenching
1992 StandoutNobel
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Tightly bound zinc in human immunodeficiency virus type 1, human T-cell leukemia virus type I, and other retroviruses
1992
Guanylyl Cyclases as a Family of Putative Odorant Receptors
2000
Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes
1993
Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance
1998 StandoutScience
Peptidyl Epoxides: Novel Selective Inactivators of Cysteine Proteases1
1996
Transition State Analogy of Phosphonic Acid Peptide Inhibitors of Pepsin
1996
Phosphoramidites: Marvellous Ligands in Catalytic Asymmetric Conjugate Addition
2000 StandoutNobel
Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid
1991
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Asymmetric Catalysis with Heterobimetallic Compounds
1997
The Unenlarged Lymph Nodes of HIV-1–infected, Asymptomatic Patients with High CD4 T Cell Counts Are Sites for Virus Replication and CD4 T Cell Proliferation. The Impact of Highly Active Antiretroviral Therapy
1998 StandoutNobel
Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites
1993 StandoutNobel
Pathogenesis of human immunodeficiency virus infection
1993
A Field Guide to Foldamers
2001 Standout
Mutational replacements of the amino acid residues forming the hydrophobic S4 binding pocket of subtilisin 309 from Bacillus lentus
1993 StandoutNobel
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Emotion Circuits in the Brain
2000 Standout
Dissociative inhibition of dimeric enzymes. Kinetic characterization of the inhibition of HIV-1 protease by its COOH-terminal tetrapeptide
1991
New Chiral Phosphorus Ligands for Enantioselective Hydrogenation
2003 Standout
What Can We Learn from Molecular Recognition in Protein–Ligand Complexes for the Design of New Drugs?
1996
Interdependency of the binding subsites in subtilisin
1992
Activatable Photosensitizers for Imaging and Therapy
2010 Standout
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Light-Directed, Spatially Addressable Parallel Chemical Synthesis
1991 StandoutScience
Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site
1993 StandoutNobel
Novel Fluorogenic Substrates for Assaying Retroviral Proteases by Resonance Energy Transfer
1990 Science
One-Pot Sequential Asymmetric Hydrogenation Utilizing Rh(I) and Ru(II) Catalysts
1998
Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 Protease
1989 Science
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity.
1994 StandoutNobel
The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations
1992
Peptidyl epoxides as selective protease inactivators
2000
Nonpeptide HIV protease inhibitors designed to replace a bound water
1993
Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments.
1991
Was läßt sich aus der molekularen Erkennung in Protein‐Ligand‐Komplexen für das Design neuer Wirkstoffe lernen?
1996
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Synthesis of Proteins by Native Chemical Ligation
1994 StandoutScience
α-Ketocarbonyl Peptides: A General Approach to Reactive Resin-Bound Intermediates in the Synthesis of Peptide Isosteres for Protease Inhibitor Screening on Solid Support
2001 StandoutNobel
Introduction of [2]Catenanes into Langmuir Films and Langmuir−Blodgett Multilayers. A Possible Strategy for Molecular Information Storage Materials
1999 StandoutNobel
1,1‘-Binaphthyl Dimers, Oligomers, and Polymers: Molecular Recognition, Asymmetric Catalysis, and New Materials
1998 Standout
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Asymmetric Synthesis of Chiral Organofluorine Compounds: Use of Nonracemic Fluoroiodoacetic Acid as a Practical Electrophile and Its Application to the Synthesis of Monofluoro Hydroxyethylene Dipeptide Isosteres within a Novel Series of HIV Protease Inhibitors
2001
Works of Michael L. Moore being referenced
Peptide substrates and inhibitors of the HIV-1 protease
1989
Chromophoric peptide substrates for the spectrophotometric assay of HIV-1 protease
1990
Protein kinase C and receptor kinase gene expression in olfactory receptor neurons
1997
Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues
1990 Nature
Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease
1992
Inactivation of HIV-1 protease by a tripeptidyl epoxide
1992
Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors.
1989
Substrate-based inhibitors of HIV-1 protease
1993
Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease.
1989