Citation Impact
Citing Papers
Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry
2008 Science
Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins
2008 StandoutNobel
Ten things you should know about protein kinases: IUPHAR R eview 14
2015
Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
2012 Standout
Development and Implementation of a Miniaturized High-Throughput Time-Resolved Fluorescence Energy Transfer Assay to Identify Small Molecule Inhibitors of Polo-Like Kinase 1
2007
Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian In Vitro System
2007
Soft corrugated channel with synergistic exclusive discrimination gating for CO2 recognition in gas mixture
2023 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
mTOR Signaling in Growth Control and Disease
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Halogen Bonding at the Active Sites of Human Cathepsin L and MEK1 Kinase: Efficient Interactions in Different Environments
2011
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Rethinking amide bond synthesis
2011 StandoutNature
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
2013 Standout
Mixed Polymer Brushes by Sequential Polymer Addition: Anchoring Layer Effect
2004
Proteasome-Mediated Processing of Nrf1 Is Essential for Coordinate Induction of All Proteasome Subunits and p97
2014
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Selective, rapid and optically switchable regulation of protein function in live mammalian cells
2015
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
2014 Standout
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
2011
Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1
2008
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
2008
Targeting cancer with small molecule kinase inhibitors
2008 Standout
A field guide to bacterial swarming motility
2010 Standout
Memory of viral infections by CRISPR-Cas adaptive immune systems: Acquisition of new information
2012 StandoutNobel
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes
2015 StandoutNobel
Using transcriptome sequencing to identify mechanisms of drug action and resistance
2012
Dynamics and functions of lipid droplets
2018 Standout
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
The road less traveled: modulating signal transduction enzymes by inhibiting their protein–protein interactions
2009
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Universal sample preparation method for proteome analysis
2009 Standout
A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity
2013
Common pitfalls in preclinical cancer target validation
2017 StandoutNobel
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
2012
Cleaning up in the endoplasmic reticulum: ubiquitin in charge
2014
Targeting Echinococcus multilocularis Stem Cells by Inhibition of the Polo-Like Kinase EmPlk1
2014
Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System
2012 StandoutNobel
Polo and Aurora kinases — lessons derived from chemical biology
2008
Molecular Recognition in Chemical and Biological Systems
2015
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity
2015 StandoutNobel
Emerging applications of stimuli-responsive polymer materials
2010 Standout
Retrograde transport pathways utilised by viruses and protein toxins
2006
Cell cycle kinases as therapeutic targets for cancer
2009
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity
2009
Rings in Drugs
2014 Standout
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
2012 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Genetic Requirements for Potassium Ion-Dependent Colony Spreading inBacillus subtilis
2005
ER-associated degradation: Protein quality control and beyond
2014
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
2019 StandoutNobel
Echinococcosis: Advances in the 21st Century
2019 Standout
Polymer Brushes via Surface-Initiated Controlled Radical Polymerization: Synthesis, Characterization, Properties, and Applications
2009 Standout
A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling
2012
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
2016 StandoutNobel
Polymer Grafting via ATRP Initiated from Macroinitiator Synthesized on Surface
2004
Cholera Toxin: An Intracellular Journey into the Cytosol by Way of the Endoplasmic Reticulum
2010
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The Halogen Bond
2016 Standout
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
2009
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
2007 StandoutNobel
Analysis of the Mouse Liver Proteome Using Advanced Mass Spectrometry
2007
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Red-Shifting Azobenzene Photoswitches for in Vivo Use
2015 Standout
Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination
2014 StandoutNobel
mTOR signaling at a glance
2009 Standout
Works of Michael Kothe being referenced
Role of p97 AAA-ATPase in the Retrotranslocation of the Cholera Toxin A1 Chain, a Non-ubiquitinated Substrate
2005
Research Article: Selectivity‐determining Residues in Plk1
2007
Beyond the MEK-pocket: Can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?
2008
Direct demonstration of carbamoyl phosphate formation on the C‐terminal domain of carbamoyl phosphate synthetase
2004
Nucleotide recognition in the ATP‐grasp protein carbamoyl phosphate synthetase
2004
Identification of Allosteric PIF‐Pocket Ligands for PDK1 using NMR‐Based Fragment Screening and 1H‐15N TROSY Experiments
2009
Structure of the Catalytic Domain of Human Polo-like Kinase 1,
2007
Structural Determinants for Inhibitor Specificity and Selectivity in PDE2A Using the Wheat Germ in Vitro Translation System
2005
Examination of poly(butadiene epoxide)-coatings on inorganic surfaces
1999