Citation Impact
Citing Papers
Human Hypertension Caused by Mutations in WNK Kinases
2001 StandoutScience
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Is there a role for glucocorticoid receptor beta in asthma?
2000
Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system
1993
Severe loss‐of‐function mutations in the adrenocorticotropin receptor (ACTHR, MC2R) can be found in patients diagnosed with salt‐losing adrenal hypoplasia
2006
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
Pluripotent Stem Cells for the Study of CNS Development
2011
Photochemical Restoration of Visual Responses in Blind Mice
2012
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
Evidence That the β-Isoform of the Human Glucocorticoid Receptor Does Not Act as a Physiologically Significant Repressor
1997
The pharmacogenetics of asthma: a candidate gene approach
2001
Reprogramming of human somatic cells to pluripotency with defined factors
2007 StandoutNature
Differential Inhibition of 17α-Hydroxylase and 17,20-Lyase Activities by Three Novel Missense CYP17 Mutations Identified in Patients with P450c17 Deficiency
2002
Molecular Mechanisms of Human Hypertension
2001 Standout
Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice
2009
Cushing's syndrome
2015 Standout
Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy.
1994
Hallmarks of aging: An expanding universe
2023 Standout
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
Absence of Glucocorticoid Receptor-β in Mice
1997
Organoid Models and Applications in Biomedical Research
2015 Standout
Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs
2012
Injury Induces Endogenous Reprogramming and Dedifferentiation of Neuronal Progenitors to Multipotency
2017
Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex
2000 Standout
Glucocorticoid Feedback Resistance
1997
Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women
2004
Cytogenetic and microsatellite alterations in tumors from patients with the syndrome of myxomas, spotty skin pigmentation, and endocrine overactivity (Carney complex).
1996
Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development
2008
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Molecular Determinants of Glucocorticoid Receptor Function and Tissue Sensitivity to Glucocorticoids
1996
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
Neonatal Complete Generalized Glucocorticoid Resistance and Growth Hormone Deficiency Caused by a Novel Homozygous Mutation in Helix 12 of the Ligand Binding Domain of the Glucocorticoid Receptor Gene (NR3C1)
2009
Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans.
1995
Inhibition of mineralocorticoid activity by the β-isoform of the human glucocorticoid receptor
1997
Familial/Sporadic Glucocorticoid Resistance: Clinical Phenotype and Molecular Mechanisms
2004
Disease Gene Candidates Revealed by Expression Profiling of Retinal Ganglion Cell Development
2007
Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia
2003
The development of allergic inflammation
2008 StandoutNature
Genetic dissection of glucocorticoid receptor function in mice
1998
Long-term treatment with RU486 and glucocorticoid receptor resistance Theoretical and therapeutic implications
1992
The Classical Complement Cascade Mediates CNS Synapse Elimination
2007 Standout
The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders
2000
Discovering Endophenotypes for Major Depression
2004
The Cholinesterases: From Genes to Proteins
1994
Mitochondrial function and redox control in the aging eye: Role of MsrA and other repair systems in cataract and macular degenerations
2008
Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man
1994 Standout
Mechanisms of Corticosteroid Resistance in Rheumatoid Arthritis
2002
Functional implications of brain corticosteroid receptor diversity
1993
Pathologic Human GR Mutant Has a Transdominant Negative Effect on the Wild-Type GR by Inhibiting Its Translocation into the Nucleus: Importance of the Ligand-Binding Domain for Intracellular GR Trafficking
2001
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
A Fresh Look at iPS Cells
2009 StandoutNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
A ROCK inhibitor permits survival of dissociated human embryonic stem cells
2007 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
The Origin and Functions of Multiple Human Glucocorticoid Receptor Isoforms
2004
Matrix metalloproteinases A review of their structure and role in acute coronary syndrome
2003
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
The inflammatory reflex
2002 StandoutNature
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
The molecular neurobiology of depression
2008 StandoutNature
Hormonal Regulation of Human Corticotropin-Releasing Hormone Gene Expression: Implications for the Stress Response and Immune/Inflammatory Reaction
1994
Modeling Development and Disease with Organoids
2016 Standout
The Human Glucocorticoid Receptor β Isoform
1996
Glucocorticoid Receptor Isoforms α and β in in Vitro Cytokine-induced Glucocorticoid Insensitivity
2004
Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjögren's syndrome
2004
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Molecular Genetics of Human Blood Pressure Variation
1996 Science
Carney Complex, Peutz-Jeghers Syndrome, Cowden Disease, and Bannayan-Zonana Syndrome Share Cutaneous and Endocrine Manifestations, But Not Genetic Loci
1998
From Progenitors to Differentiated Cells in the Vertebrate Retina
2009
Syndromes of Glucocorticoid Resistance
1993
In Situ Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications
2004 StandoutNobel
Drosophila Bestrophin-1 Chloride Current Is Dually Regulated by Calcium and Cell Volume
2007
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency*
2000
Pharmacogenetics and asthma: false hope or new dawn?: Table 1—
2007
GLUCOCORTICOID AND MINERALOCORTICOID RECEPTORS: Biology and Clinical Relevance
1997
Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins
1993
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress
1997 StandoutScience
Expression and Subcellular Distribution of the β-Isoform of the Human Glucocorticoid Receptor*
1997
Stem cells in retinal regeneration: past, present and future
2013
Genetics of Carney complex and related familial lentiginoses, and other multiple tumor syndromes
2000
Disease Tolerance as a Defense Strategy
2012 StandoutScience
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
Paradoxical Response to Dexamethasone in the Diagnosis of Primary Pigmented Nodular Adrenocortical Disease
1999
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Rescue of Volume-regulated Anion Current by Bestrophin Mutants with Altered Charge Selectivity
2008
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Neuroendocrine Regulation of Immunity
2002
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner
1998 StandoutNobel
Resetting of Circadian Time in Peripheral Tissues by Glucocorticoid Signaling
2000 StandoutScience
Brain Corticosteroid Receptor Balance in Health and Disease*
1998 Standout
SPECIFIC, NONGENOMIC ACTIONS OF STEROID HORMONES
1997
Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance
2001
Emerging Targets in Photopharmacology
2016 StandoutNobel
Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
2013
The Influence of Social Hierarchy on Primate Health
2005 StandoutScience
Regulation and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis: The Corticotropin-Releasing Hormone Perspective
1992
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Identification of a Novel Genetic Locus for Familial Cardiac Myxomas and Carney Complex
1998
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Works of Michael Karl being referenced
The Non-Ligand Binding β-Isoform of the Human Glucocorticoid Receptor (hGRβ): Tissue Levels, Mechanism of Action, and Potential Physiologic Role
1996
Three-Dimensional Neuroepithelial Culture from Human Embryonic Stem Cells and Its Use for Quantitative Conversion to Retinal Pigment Epithelium
2013
Estrogen-Related Abnormalities in Glomerulosclerosis-Prone Mice
2002
Differential Hormone-Dependent Transcriptional Activation and -Repression by Naturally Occurring Human Glucocorticoid Receptor Variants
1997
Molecular analysis of duplicated esterase genes in Drosophila melanogaster.
1990
Baf60c is a component of the neural progenitor‐specific BAF complex in developing retina
2008
Imbalanced Expression of the Glucocorticoid Receptor Isoforms in Cultured Lymphocytes from a Patient with Systemic Glucocorticoid Resistance and Chronic Lymphocytic Leukemia
1999
Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.
1996
Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
1991
Nelson's syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene.
1996
Neural Regeneration and Cell Replacement: A View from the Eye
2008
Estrogen Deficiency Accelerates Progression of Glomerulosclerosis in Susceptible Mice
2003
Ion channels in the RPE
2007
Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance
1997
Localization and expression of adrenocorticotropic hormone receptor mRNA in normal and neoplastic human adrenal cortex
1998
Glucocorticosteroid Resistance in Humans. Elucidation of the Molecular Mechanisms and Implications for Pathophysiology
1994
Structural analysis of the regulatory region of the human corticotropin releasing hormone gene
1990
Androgen Receptor-Mediated Hypersensitivity to Androgens in Women with Nonhyperandrogenic Hirsutism: Skewing of X-Chromosome Inactivation1
1999
Expression and Regulation of Estrogen Receptors in Mesangial Cells
2001
Molecular Mechanisms of Clucocorticoid Resistance/Hypersensitivity: Potential Clinical Implications
1996
Clonal composition of human adrenocortical neoplasms.
1994
Stimulation of neural regeneration in the mouse retina
2008
Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation.
1996
Physiological and molecular aspects of mineralocorticoid receptor action in pseudohypoaldosteronism: a responsiveness test and therapy.
1994
Efficient generation of retinal progenitor cells from human embryonic stem cells
2006
Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene
1993
The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action, and potential physiologic role.
1996
Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.
1993
The Light Peak of the Electroretinogram Is Dependent on Voltage-gated Calcium Channels and Antagonized by Bestrophin (Best-1)
2006