Citation Impact

Citing Papers

Structural basis of biological nitrogen fixation
2005
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
RNA-Dependent Cysteine Biosynthesis in Archaea
2005 Science
The Human SepSecS-tRNA Sec Complex Reveals the Mechanism of Selenocysteine Formation
2009 StandoutScienceNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Energy analysis of chemistry for correct insertion by DNA polymerase β
2006
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
A suite of designed protein cages using machine learning and protein fragment-based protocols
2024
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Synthetic Analogues and Reaction Systems Relevant to the Molybdenum and Tungsten Oxotransferases
2003
Magnesium-cationic Dummy Atom Molecules Enhance Representation of DNA Polymerase β in Molecular Dynamics Simulations: Improved Accuracy in Studies of Structural Features and Mutational Effects
2006 StandoutNobel
Protein design automation
1996
Molybdenum and tungsten in biology
2002
Architecture and active site of particulate methane monooxygenase
2012
Localization of a Catalytic Intermediate Bound to the FeMo-cofactor of Nitrogenase
2004
Crystal Structure of the Gephyrin-related Molybdenum Cofactor Biosynthesis Protein MogA from Escherichia coli
2000
Iron Coordination Structures of Oxygen Sensor FixL Characterized by Fe K-edge Extended X-ray Absorption Fine Structure and Resonance Raman Spectroscopy
1999
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Breaking the N2 triple bond: insights into the nitrogenase mechanism
2006
Molybdenum enzymes, their maturation and molybdenum cofactor biosynthesis in Escherichia coli
2012
Mutagenicity, toxicity and repair of DNA base damage induced by oxidation
2003
Magnesium-Induced Assembly of a Complete DNA Polymerase Catalytic Complex
2006
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
One Molecule of Molybdopterin Guanine Dinucleotide is Associated with Each Subunit of the Heterodimeric Mo‐Fe‐S Protein Transhydroxylase of Pelobacter acidigallici as Determined by SDS/PAGE and Mass Spectrometry
1996
Cold adaptation of the mononuclear molybdoenzyme periplasmic nitrate reductase from the Antarctic bacterium Shewanella gelidimarina
2011
X-ray crystal structure of the nitrogenase molybdenum-iron protein from Clostridium pasteurianum at 3.0-.ANG. resolution
1993
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Comparative genomics and evolution of molybdenum utilization
2011
Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates
2010
Nitrogenase assembly
2012
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
The history of the discovery of the molybdenum cofactor and novel aspects of its biosynthesis in bacteria
2010
Protein thermostability in extremophiles
1998
Finding and using hyperthermophilic enzymes
1998
Oxidation of methane by a biological dicopper centre
2010 Nature
The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death
2003
Active DNA demethylation: many roads lead to Rome
2010
New insights into structure-function relationships in nitrogenase: a 1.6 Å resolution X-ray crystallographic study of Klebsiella pneumoniae MoFe-protein
1999
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Characterization of Crystalline Formate Dehydrogenase H from Escherichia coli
1996
High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers
2019
Molecular cloning of dimethyl sulfoxide reductase from Rhodobacter sphaeroides
1996
Proliferation-dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4
2004
The Tungsten Formylmethanofuran Dehydrogenase from Methanobacterium Thermoautotrophicum Contains Sequence Motifs Characteristic for Enzymes Containing Molybdopterin Dinucleotide
1995
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Rhodobacter capsulatus XdhC Is Involved in Molybdenum Cofactor Binding and Insertion into Xanthine Dehydrogenase
2006
Electrochemical study of the redox properties of [2Fe‐2S] ferredoxins Evidence for superreduction of the Rieske [2Fe‐2S] cluster
1995
Copper A of Cytochrome c Oxidase, A Novel, Long‐Embattled, Biological Electron‐Transfer Site
1997
Natural expansion of the genetic code
2006
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
C → T mutagenesis and γ‐radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases
2005 StandoutNobel
Adding New Chemistries to the Genetic Code
2010
The consequences of an interstitial N atom in the FeMo cofactor of nitrogenase
2003
Involvement of the Molybdenum Cofactor Biosynthetic Machinery in the Maturation of the Escherichia coli Nitrate Reductase A
2004
Differential Specificity of Human and Escherichia coli Endonuclease III and VIII Homologues for Oxidative Base Lesions
2004
Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC
2000
Structure of the molybdopterin-bound Cnx1G domain links molybdenum and copper metabolism
2004 Nature
Structure and Specificity of the Vertebrate Anti-Mutator Uracil-DNA Glycosylase SMUG1
2003
Structures of apo and GTP-bound molybdenum cofactor biosynthesis protein MoaC fromThermus thermophilusHB8
2010
Nonredundant Roles of the mPer1 and mPer2 Genes in the Mammalian Circadian Clock
2001
Nitrogenase reduction of carbon-containing compounds
2013
Molybdoproteomes and Evolution of Molybdenum Utilization
2008
Nitrogenase and biological nitrogen fixation
1994
Germline transmission of RNAi in mice
2003
Crystal structure of oxidized trimethylamine N -oxide reductase from Shewanella massilia at 2.5 å resolution 1 1Edited by R. Huber
1998
A DNA metalloenzyme with DNA ligase activity
1995 StandoutNatureNobel
DNA Replication Fidelity
2004
[26] X-Ray absorption spectroscopy and applications in structural biology
1995
Pyrrolysine analogues as substrates for pyrrolysyl‐tRNA synthetase
2006
Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeonMethanosarcina mazei
2006
The Molybdenum Nitrogenase from Wild‐type Xanthobacter autotrophicus Exhibits Properties Reminiscent of Alternative Nitrogenases
1995
Bacterial sensors of oxygen
2009
Revealing the world of RNA interference
2004 StandoutNatureNobel
The prokaryotic complex iron–sulfur molybdoenzyme family
2007
Tungsten in biological systems
1996
Highly Organized but Pliant Active Site of DNA Polymerase β: Compensatory Mechanisms in Mutant Enzymes Revealed by Dynamics Simulations and Energy Analyses
2004
Molecular Basis of Sulfite Oxidase Deficiency from the Structure of Sulfite Oxidase
1997
Activation-induced Cytidine Deaminase Deaminates 5-Methylcytosine in DNA and Is Expressed in Pluripotent Tissues
2004
A structural comparison of molybdenum cofactor-containing enzymes
1998
The transcription factor, NFI/CTF plays a positive regulatory role in expression of the hSMUG1 gene
2003
Perspectives on Oxygen Sensing
1999 StandoutNobel
Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylase
2004
The substrate binding cavity of particulate methane monooxygenase from Methylosinus trichosporium OB3b expresses high enantioselectivity for n-butane and n-pentane oxidation to 2-alcohol
2011
Substrate specificity and evolutionary implications of a NifDK enzyme carrying NifB‐co at its active site
2010
The direct genetic encoding of pyrrolysine
2005
XAFS studies of nitrogenase: the MoFe and VFe proteins and the use of crystallographic coordinates in three-dimensional EXAFS data analysis
2002
hUNG2 Is the Major Repair Enzyme for Removal of Uracil from U:A Matches, U:G Mismatches, and U in Single-stranded DNA, with hSMUG1 as a Broad Specificity Backup
2002
Properties of Xanthine Dehydrogenase Variants from Rosy Mutant Strains of Drosophila melanogaster and their Relevance to the enzyme's Structure and Mechanism
1996
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Crystal structure of a pol α family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp . 9°N-7 1 1Edited by D. Rees
2000
The Crystal Structure of the Escherichia coliMobA Protein Provides Insight into Molybdopterin Guanine Dinucleotide Biosynthesis
2000
A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism
2008
Crystal structure of the first dissimilatory nitrate reductase at 1.9 Å solved by MAD methods
1999 Nobel
Probing the Hydrophobic Pocket of the Active Site in the Particulate Methane Monooxygenase (pMMO) from Methylococcus capsulatus (Bath) by Variable Stereoselective Alkane Hydroxylation and Olefin Epoxidation
2008
Electron Transfer within Nitrogenase: Evidence for a Deficit-Spending Mechanism
2011
Crystal Structure of the Xanthine Oxidase-Related Aldehyde Oxido-Reductase from D. gigas
1995 ScienceNobel
Mammalian Oxygen Sensing, Signalling and Gene Regulation
2000
Comprehensive Assessment of the Regulons Controlled by the FixLJ-FixK2-FixK1Cascade inBradyrhizobium japonicum
2008
Structural, Spectroscopic, and Redox Consequences of a Central Ligand in the FeMoco of Nitrogenase:  A Density Functional Theoretical Study
2003
High resolution 1s core hole X-ray spectroscopy in 3d transition metal complexes—electronic and structural information
2004
On carboxylate as a leaving group at the active site of Mo nitrogenase: electrochemical reactions of some MO and W carboxylates, formation of mono-, di- and tri-hydrides and the detection of an MoH2(N2) intermediate
1994
Spectroscopic studies of molybdenum and tungsten enzymes
2011
A methyldiazene (HNNCH 3 )-derived species bound to the nitrogenase active-site FeMo cofactor: Implications for mechanism
2006
Evidence for a dynamic role for homocitrate during nitrogen fixation: the effect of substitution at the α-Lys426 position in MoFe-protein of Azotobacter vinelandii
2006
Copper Active Sites in Biology
2014 Standout
Comparison of the Reactivity of Bis(μ-oxo)CuIICuIII and CuIIICuIII Species to Methane
2008
Modeling the Tungsten Sites of Inactive and Active Forms of Hyperthermophilic Pyrococcus furiosus Aldehyde Ferredoxin Oxidoreductase
1996
Orbital interactions, electron delocalization and spin coupling in iron-sulfur clusters
1995
A new approach to identifying substrate binding sites on isolated FeMo-cofactor of nitrogenase
1997 StandoutNobel
Assembly of Nitrogenase MoFe Protein
2008
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
The Metal Centers of Particulate Methane Monooxygenase from Methylosinus trichosporium OB3b
2008
Theoretical Investigation of the Binding Free Energies and Key Substrate-Recognition Components of the Replication Fidelity of Human DNA Polymerase β
2002 StandoutNobel
Metal-hydroxycarboxylate interactions: syntheses and structures of K2[VO2(C6H6O7)]2·4H2O and (NH4)2[VO2(C6H6O7)]2·2H2O
1995
Biosynthesis of the Iron-Molybdenum Cofactor of Nitrogenase
2008
Formation and Insertion of the Nitrogenase Iron−Molybdenum Cofactor
2003
Structural aspects of mononuclear Mo/W-enzymes
2010
57Fe ENDOR Spectroscopy and ‘Electron Inventory’ Analysis of the Nitrogenase E4Intermediate Suggest the Metal-Ion Core of FeMo-Cofactor Cycles Through Only One Redox Couple
2011
Catalysis by Enzymes: The Biological Ammonia Synthesis
2006
Selenol binds to iron in nitrogenase iron-molybdenumcofactor: an extended x-ray absorption fine structure study.
1994
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine
2004
Large scale isolation and characterization of the molybdenum-iron cluster from nitrogenase.
1994
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Refinement of a Model for the Nitrogenase MoFe Cluster Using Single‐Crystal Mo and Fe EXAFS
1993
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
2007 StandoutNobel
Computer Simulation of the Chemical Catalysis of DNA Polymerases:  Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Trapping an Intermediate of Dinitrogen (N2) Reduction on Nitrogenase
2009
FeMo Cofactor of Nitrogenase:  A Density Functional Study of States MN, MOX, MR, and MI
2001
Mechanism of Molybdenum Nitrogenase
1996 Standout
Nitrogenase of Klebsiella pneumoniae: electron nuclear double resonance (ENDOR) studies on the substrate reduction site
1994
Structure and Mechanism of DNA Polymerase β
2006
PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light
1999
Formation of an all ferrous Fe4S4 cluster in the iron protein component of Azotobacter vinelandii nitrogenase
1994
Tungstoenzymes
1996
Mechanism of Nitrogen Fixation by Nitrogenase: The Next Stage
2014 Standout
Evidence for Oxygen Binding at the Active Site of Particulate Methane Monooxygenase
2012
Two-Component Signal Transduction
2000 Standout
Efficient Room‐Temperature Oxidation of Hydrocarbons Mediated by Tricopper Cluster Complexes with Different Ligands
2012
Electron transfer precedes ATP hydrolysis during nitrogenase catalysis
2013
Site-directed Mutagenesis of Recombinant Sulfite Oxidase
1996
Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells
2004 StandoutNobel
A Reexamination of the Nucleotide Incorporation Fidelity of DNA Polymerases
2002
Dinitrogen Coordination Chemistry:  On the Biomimetic Borderlands
2004
Pyrrolysine is not hardwired for cotranslational insertion at UAG codons
2007
Molecular structure of a mono-peroxo vanadium(V) complex formed by d,l-lactic acid
2000
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Structure of the FeFe-cofactor of the iron-only nitrogenase and possible mechanism for dinitrogen reduction
2004
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
2009
Nitrogenase MoFe-Protein at 1.16 Å Resolution: A Central Ligand in the FeMo-Cofactor
2002 Science
Modeling a Central Ligand in the Nitrogenase FeMo Cofactor
2003
Crystal Structure of DMSO Reductase: Redox-Linked Changes in Molybdopterin Coordination
1996 Science
Computer simulations of protein functions: Searching for the molecular origin of the replication fidelity of DNA polymerases
2005 StandoutNobel
The cancer connection
2002 StandoutNatureNobel
Controlled Oxidation of Hydrocarbons by the Membrane-Bound Methane Monooxygenase: The Case for a Tricopper Cluster
2008
Nitrogen fixation in solution
1995
Mammalian 5-Formyluracil−DNA Glycosylase. 1. Identification and Characterization of a Novel Activity That Releases 5-Formyluracil from DNA
2003
The Mononuclear Molybdenum Enzymes
1996 Standout
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Metal Substitution in the Active Site of Nitrogenase MFe7S9 (M = Mo4+, V3+, Fe3+)
2002
Molybdenum Triamidoamine Complexes that Contain Hexa-tert-butylterphenyl, Hexamethylterphenyl, or p-Bromohexaisopropylterphenyl Substituents. An Examination of Some Catalyst Variations for the Catalytic Reduction of Dinitrogen
2004 StandoutNobel
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Iron-Sulfur Clusters: Nature's Modular, Multipurpose Structures
1997 StandoutScience
Biosynthesis of the Metalloclusters of Molybdenum Nitrogenase
2011
Nitrogenase metalloclusters: structures, organization, and synthesis
1993
The DMSO Reductase Family of Microbial Molybdenum Enzymes; Molecular Properties and Role in the Dissimilatory Reduction of Toxic Elements
2002
A General Strategy for the Semisynthesis of Ratiometric Fluorescent Sensor Proteins with Increased Dynamic Range
2016
Dalton perspectives. Metals in the nitrogenases
1994
A Water-Mediated and Substrate-Assisted Catalytic Mechanism forSulfolobus solfataricusDNA Polymerase IV
2007
Chemical Activity of the Nitrogenase FeMo Cofactor with a Central Nitrogen Ligand:  Density Functional Study
2004
Structural Basis of Biological Nitrogen Fixation
1996
Structure−Function Relationships of Alternative Nitrogenases
1996
The Mononuclear Molybdenum Enzymes
2014 Standout
Catalytic Reduction of Dinitrogen to Ammonia at a Single Molybdenum Center
2003 StandoutScienceNobel
P+ State of Nitrogenase P-Cluster Exhibits Electronic Structure of a [Fe4S4]+ Cluster
2012
Mammalian 5-Formyluracil−DNA Glycosylase. 2. Role of SMUG1 Uracil−DNA Glycosylase in Repair of 5-Formyluracil and Other Oxidized and Deaminated Base Lesions
2003
Efficient catalytic oxidation of hydrocarbons mediated by tricopper clusters under mild conditions
2012
Cation-Deficient Spinel ZnMn2O4 Cathode in Zn(CF3SO3)2 Electrolyte for Rechargeable Aqueous Zn-Ion Battery
2016 Standout
Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas
2003 StandoutNobel
Molybdenum enzymes in bacteria and their maturation
2011
Ab initio phase determination and phase extension using non-crystallographic symmetry
1995
A Theoretical Model for the Active Site of Nitrogenase
1996
Periplasmic nitrate reductases and formate dehydrogenases: Biological control of the chemical properties of Mo and W for fine tuning of reactivity, substrate specificity and metabolic role
2012
Bioinorganic chemistry of molybdenum and tungsten enzymes: A structural–functional modeling approach
2010
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Metalloenzymes, Structural Motifs, and Inorganic Models
1993 Science
How N2 Might Be Activated by the FeMo‐Cofactor in Nitrogenase
1993 Nobel
On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution
2008 StandoutNobel
Mössbauer Studies of the Membrane-Associated Methane Monooxygenase from Methylococcus capsulatus Bath:  Evidence for a Diiron Center
2007
Evolutionary Persistence of the Molybdopyranopterin-Containing Sulfite Oxidase Protein Fold
2008
Transition Metal Complexes That Contain a Triamidoamine Ligand
1997 StandoutNobel
Catalytic Reduction of Hydrazine to Ammonia with MoFe3S4−Polycarboxylate Clusters. Possible Relevance Regarding the Function of the Molybdenum-Coordinated Homocitrate in Nitrogenase
1996
Molybdenum−Iron Sulfide-Bridged Double Cubanes
1997
Structure and Reversible Pyran Formation in Molybdenum Pyranopterin Dithiolene Models of the Molybdenum Cofactor
2012
Pyranopterin conformation defines the function of molybdenum and tungsten enzymes
2012
Tungsten in biological systems
1996
Mechanism of Mo-Dependent Nitrogenase
2009
Biological and medicinal aspects of vanadium
2003
Crystal Structure and Characterization of Particulate Methane Monooxygenase from Methylocystis species Strain M
2011
Dinitrogen Cleavage by a Three-Coordinate Molybdenum(III) Complex
1995 Science
Coordination and oxidation of vanadium(II) by 1,2-bis(2-sulfidophenylsulfanyl)ethane(2–)(S4): the structures of [V(S4)tmeda], the first example of vanadium(II)–sulfide coordination, and of [V3(µ-O)2(S2)4(tmeda)2](S2= 1,2-benzenedithiolate(2–)]
1995

Works of Michael K. Chan being referenced

A New UAG-Encoded Residue in the Structure of a Methanogen Methyltransferase
2002 Science
Specificity of Pyrrolysyl-tRNA Synthetase for Pyrrolysine and Pyrrolysine Analogs
2008
Redox Potentiometry Studies of Particulate Methane Monooxygenase: Support for a Trinuclear Copper Cluster Active Site
2007
Efficient Oxidation of Methane to Methanol by Dioxygen Mediated by Tricopper Clusters
2013
The pyrrolysine translational machinery as a genetic-code expansion tool
2011
Definitive Identification of Mammalian 5-Hydroxymethyluracil DNA N-Glycosylase Activity as SMUG1
2001
The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins
2016
A Pyrrolysine Analogue for Protein Click Chemistry
2009
Direct charging of tRNACUA with pyrrolysine in vitro and in vivo
2004 Nature
Reactivity and Chemical Synthesis of L-Pyrrolysine— the 22nd Genetically Encoded Amino Acid
2004
Recent advances in heme-protein sensors
2001
Insight into the Catalytic Mechanism of DNA Polymerase β:  Structures of Intermediate Complexes,
2001
In Vivo Enzyme Entrapment in a Protein Crystal
2020
Ligand field strengths and oxidation states from manganese L-edge spectroscopy
1991
Structure of a Hyperthermophilic Tungstopterin Enzyme, Aldehyde Ferredoxin Oxidoreductase
1995 Science
Redox Potentiometry Studies of Particulate Methane Monooxygenase: Support for a Trinuclear Copper Cluster Active Site
2007
Structure-Based Mechanism of O2 Sensing and Ligand Discrimination by the FixL Heme Domain of Bradyrhizobium japonicum,
2002
Nitrogenase: Crystal structures and function.
1993
Targeted Deletion of mNth1 Reveals a Novel DNA Repair Enzyme Activity
2002
New Mechanistic Insights from Structural Studies of the Oxygen-Sensing Domain of Bradyrhizobium japonicum FixL,
2000
The Nitrogenase FeMo-Cofactor and P-Cluster pair: 2.2 Å Resolution Structures
1993 Science
Molecular characterization of the genes encoding the tungsten-containing aldehyde ferredoxin oxidoreductase from Pyrococcus furiosus and formaldehyde ferredoxin oxidoreductase from Thermococcus litoralis
1995
Structure of a biological oxygen sensor: A new mechanism for heme-driven signal transduction
1998
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