Citation Impact
Citing Papers
Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate
2015 StandoutNobel
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
2011
Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
2014
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment
2005
Acute B lymphoblastic leukaemia‐propagating cells are present at high frequency in diverse lymphoblast populations
2012
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
c-Kit—A hematopoietic cell essential receptor tyrosine kinase
2007
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche
2016
Necroptosis and its role in inflammation
2015 StandoutNature
Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization
2005
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Cancer stem cells: never Wnt away from the niche
2008
Hematopoiesis: A Human Perspective
2012
Predicting the likelihood of an isocitrate dehydrogenase 1 or 2 mutation in diagnoses of infiltrative glioma
2014
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Ultrasensitive fluorescent proteins for imaging neuronal activity
2013 StandoutNature
Cancer stem cells revisited
2017 Standout
The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response
2010
H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias
2008
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
2016 Standout
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Mouse models of human AML accurately predict chemotherapy response
2009
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells
2012
Wnt/β-Catenin Signaling and Disease
2012 Standout
MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny
2012
Mammalian Rho GTPases: new insights into their functions from in vivo studies
2008 Standout
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells
2015
The Missing Diversity in Human Genetic Studies
2019 Standout
Prospective, high-throughput molecular profiling of human gliomas
2012
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Emerging Biological Principles of Metastasis
2017 Standout
Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
2015 Standout
Rho signaling and mechanical control of vascular development
2008
The cancer stem cell: premises, promises and challenges
2011 Standout
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs
2013
Limiting Factors in Murine Hematopoietic Stem Cell Assays
2007
Reducing mobilization of simian immunodeficiency virus based vectors by primer complementation
2004
Clonal evolution in cancer
2012 StandoutNature
Model Systems for Examining Effects of Leukemia Associated Oncogenes in Primary Human CD34+ Cells via Retroviral Transduction
2009
CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo
2017 StandoutNobel
The PI3K Pathway in Human Disease
2017 Standout
Expression and activation of αvβ3 integrins by SDF‐1/CXC12 increases the aggressiveness of prostate cancer cells
2006
Bacterial volatiles: the smell of small organisms
2007
A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
2010
Continuous Flow Reduction of Artemisinic Acid Utilizing Multi‐Injection Strategies—Closing the Gap Towards a Fully Continuous Synthesis of Antimalarial Drugs
2015
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Rho GTPases and Regulation of Hematopoietic Stem Cell Localization
2008
Toward the Synthesis of Noroxymorphone via Aerobic Palladium-Catalyzed Continuous Flow N-Demethylation Strategies
2016
3d Transition Metals for C–H Activation
2018 Standout
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development
2010 StandoutNobel
Development of a Multi-Step Synthesis and Workup Sequence for an Integrated, Continuous Manufacturing Process of a Pharmaceutical
2014
Oscillatory three-phase flow reactor for studies of bi-phasic catalytic reactions
2015
Efficient gene transfer into rhesus repopulating hematopoietic stem cells using a simian immunodeficiency virus–based lentiviral vector system
2004
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
How the Fanconi Anemia Pathway Guards the Genome
2009
From alcohol to 1,2,3-triazole via a multi-step continuous-flow synthesis of a rufinamide precursor
2016
Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy
2016
Process Intensified Flow Synthesis of 1H-4-Substituted Imidazoles: Toward the Continuous Production of Daclatasvir
2015
In‐Situ Microfluidic Study of Biphasic Nanocrystal Ligand‐Exchange Reactions Using an Oscillatory Flow Reactor
2017 StandoutNobel
Atraumatic Oral Spray Immunization with Replication-Deficient Viral Vector Vaccines
2007 StandoutNobel
Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
2018 Standout
Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population
2014
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34− fraction
2010
Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products
2015
Feedback in Flow for Accelerated Reaction Development
2016
Optimizing the Heck–Matsuda Reaction in Flow with a Constraint-Adapted Direct Search Algorithm
2016
Stem cell concepts renew cancer research
2008
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells
2015
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The Ubiquitin Code
2012 Standout
Plantwide design and economic evaluation of two Continuous Pharmaceutical Manufacturing (CPM) cases: Ibuprofen and artemisinin
2016
Oscillatory Microprocessor for Growth and in Situ Characterization of Semiconductor Nanocrystals
2015 StandoutNobel
Hydrogen Chloride Gas in Solvent-Free Continuous Conversion of Alcohols to Chlorides in Microflow
2016
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan
2012
Terpene synthases are widely distributed in bacteria
2014 StandoutNobel
Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment
2011
SERIES: Genomic instability in cancer Balancing repair and tolerance of DNA damage caused by alkylating agents
2012
Scalability of Continuous Flow Production of Metal–Organic Frameworks
2016
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton
2006
New synthetic routes towards MOF production at scale
2017 Standout
Works of Michael Jansen being referenced
Tetrahydrofolate serves as a methyl acceptor in the demethylation of dimethylsulfoniopropionate in cell extracts of sulfate-reducing bacteria
1997
A Sensitive and Specific Diagnostic Panel to Distinguish Diffuse Astrocytoma From Astrocytosis: Chromosome 7 Gain With Mutant Isocitrate Dehydrogenase 1 and p53
2011
Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMTP140K into hematopoietic stem cells
2002
The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization
2006
Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
2008
The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice
2007
Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma
2007
Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers
2010
Comparison of Three Retroviral Vector Systems for Transduction of Nonobese Diabetic/Severe Combined Immunodeficiency Mice Repopulating Human CD34 + Cord Blood Cells
2003
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M
2009
RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells
2004
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-α on Fanconi anemia hematopoietic stem and progenitor cells
2009
p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death
2007
Rac2-Deficient Hematopoietic Stem Cells Show Defective Interaction with the Hematopoietic Microenvironment and Long-Term Engraftment Failure
2005
Non-Growth-Associated Demethylation of Dimethylsulfoniopropionate by (Homo)acetogenic Bacteria
2001
Pharmaceutical Roundtable Study Demonstrates the Value of Continuous Manufacturing in the Design of Greener Processes
2013