Citation Impact
Citing Papers
Why highly expressed proteins evolve slowly
2005 StandoutNobel
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Limits of long-term selection against Neandertal introgression
2019 StandoutNobel
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Sequencing and Analysis of Neanderthal Genomic DNA
2006 StandoutScienceNobel
Local DNA Topography Correlates with Functional Noncoding Regions of the Human Genome
2009 Science
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
2005 StandoutScience
Ultraconserved Elements in the Human Genome
2004 Science
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
2009
Therapeutic strategies for tau mediated neurodegeneration
2012
Strong and Weak Male Mutation Bias at Different Sites in the Primate Genomes: Insights from the Human-Chimpanzee Comparison
2005
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001
Improvements to GALA and dbERGE II: databases featuring genomic sequence alignment, annotation and experimental results
2004
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
The Share of Human Genomic DNA under Selection Estimated from Human-Mouse Genomic Alignments
2003
Reliable prediction of regulator targets using 12 Drosophila genomes
2007
Evolution and functional classification of vertebrate gene deserts
2004
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
The genomic landscape of Neanderthal ancestry in present-day humans
2014 StandoutNatureNobel
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
2009 StandoutNature
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
Evolution and Survival on Eutherian Sex Chromosomes
2009
Functional neurogenesis in the adult hippocampus
2002 StandoutNature
Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation
2012
Widespread Genomic Signatures of Natural Selection in Hominid Evolution
2009
Genomic Regionality in Rates of Evolution Is Not Explained by Clustering of Genes of Comparable Expression Profile
2004
Involvement of chemokine receptors in breast cancer metastasis
2001 StandoutNature
Evidence for turnover of functional noncoding DNA in mammalian genome evolution
2004
Comparative Recombination Rates in the Rat, Mouse, and Human Genomes
2004
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Neurophysiological investigation of the basis of the fMRI signal
2001 StandoutNature
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Global Predictions and Tests of Erythroid Regulatory Regions
2003
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Tau in physiology and pathology
2015 Standout
The UCSC Table Browser data retrieval tool
2003 Standout
Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs
2007
Characterization of Evolutionary Rates and Constraints in Three Mammalian Genomes
2004
Analysis of Multiple Genomic Sequence Alignments: A Web Resource, Online Tools, and Lessons Learned From Analysis of Mammalian SCL Loci
2004
Physiologic and Morphologic Characteristics of Granule Cell Circuitry in Human Epileptic Hippocampus
1995
Neutral Substitutions Occur at a Faster Rate in Exons Than in Noncoding DNA in Primate Genomes
2003
Why do human diversity levels vary at a megabase scale?
2005 StandoutNobel
Phosphorylation Regulates Tau Interactions with Src Homology 3 Domains of Phosphatidylinositol 3-Kinase, Phospholipase Cγ1, Grb2, and Src Family Kinases
2008
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Detection of nonneutral substitution rates on mammalian phylogenies
2009
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
zPicture: Dynamic Alignment and Visualization Tool for Analyzing Conservation Profiles
2004
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
What fraction of the human genome is functional?
2011
Functional organization of the hippocampal longitudinal axis
2014 StandoutNobel
Patterns of Insertions and Their Covariation With Substitutions in the Rat, Mouse, and Human Genomes
2004
Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia
2007
Origin and physiological roles of inflammation
2008 StandoutNature
Human–Mouse Alignments with BLASTZ
2002
Mutation rate variation in the mammalian genome
2003
Microglia as neuroprotective, immunocompetent cells of the CNS
2002
Tau protein and the neurofibrillary pathology of Alzheimer's disease
1993
Phylogenetic Estimation of Context-Dependent Substitution Rates by Maximum Likelihood
2003
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Identification and Characterization of Multi-Species Conserved Sequences
2003
A Neutral Explanation for the Correlation of Diversity with Recombination Rates in Humans
2003 StandoutNobel
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease
2004
Distribution and intensity of constraint in mammalian genomic sequence
2005
Evaluation of regulatory potential and conservation scores for detecting cis -regulatory modules in aligned mammalian genome sequences
2005
The Human Condition—A Molecular Approach
2014 StandoutNobel
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
2005 Standout
Gene Expression, Synteny, and Local Similarity in Human Noncoding Mutation Rates
2004
EEG-triggered functional MRI of interictal epileptiform activity in patients with partial seizures
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Neurodegenerative Tauopathies
2001 Standout
Mammalian Neural Stem Cells
2000 StandoutScience
Parallel Patterns of Evolution in the Genomes and Transcriptomes of Humans and Chimpanzees
2005 StandoutScienceNobel
Gene Expression Intensity Shapes Evolutionary Rates of the Proteins Encoded by the Vertebrate Genome
2004
Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus
1997 Standout
Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals
2016 StandoutScienceNobel
Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
1998
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
A GATA-1-regulated microRNA locus essential for erythropoiesis
2008
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
2012
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
2007
Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
2014
Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons.
1996
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
1996 StandoutNature
In Vivo Distribution of the Human Immunodeficiency Virus/Simian Immunodeficiency Virus Coreceptors: CXCR4, CCR3, and CCR5
1998
Pharmacokinetics and Safety of AMD-3100, a Novel Antagonist of the CXCR-4 Chemokine Receptor, in Human Volunteers
2000
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
1998 Standout
Generation times in wild chimpanzees and gorillas suggest earlier divergence times in great ape and human evolution
2012 StandoutNobel
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture
2010 StandoutScienceNobel
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets
2009 StandoutNobel
Works of Michael J. O’Connor being referenced
Localization of subclinical ictal activity by functional magnetic resonance imaging: Correlation with invasive monitoring
1995
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
1994
Covariation in Frequencies of Substitution, Deletion, Transposition, and Recombination During Eutherian Evolution
2003
Distinguishing Regulatory DNA From Neutral Sites
2003
NMDA receptor activation during epileptiform responses in the dentate gyrus of epileptic patients
1991
Hippocampal Cell Distributions in Temporal Lobe Epilepsy: A Comparison Between Patients With and Without an Early Risk Factor
1996
In vitro evidence for a dual role of tumor necrosis factor‐α in human immunodeficiency virus type 1 encephalopathy
1995
Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates
1999
CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons.
1997