Citation Impact
Citing Papers
Topographical and Temporal Diversity of the Human Skin Microbiome
2009 StandoutScience
Topical tofacitinib for atopic dermatitis: a phase II a randomized trial
2016
Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy
2020
Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
2012 StandoutScience
A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis
2013
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
2017 Standout
Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis
2009
Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis
2014
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Inference and analysis of cell-cell communication using CellChat
2021 Standout
Cationic Host Defence Peptides: Potential as Antiviral Therapeutics
2013
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis
2020
Control of somatic tissue differentiation by the long non-coding RNA TINCR
2012 StandoutNature
Atopic Dermatitis
2008 Standout
Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin
2009
IL-31: A new link between T cells and pruritus in atopic skin inflammation
2006 Standout
Absence of T-regulatory cell expression and function in atopic dermatitis skin
2005
Psoriasis
2009 Standout
Activation of TLR2 by a Small Molecule Produced by Staphylococcus epidermidis Increases Antimicrobial Defense against Bacterial Skin Infections
2010
Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis
2012
Pathogenesis and clinical features of psoriasis
2007 Standout
“Outside-to-Inside” (and Now Back to “Outside”) Pathogenic Mechanisms in Atopic Dermatitis
2008
Human Genetics Shape the Gut Microbiome
2014 Standout
The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
2013 StandoutNobel
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
2008 Standout
Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function
2011
Atopic dermatitis
2015 Standout
Molecular basis of atopic dermatitis
2007
Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells
2006
Filaggrin Mutations Associated with Skin and Allergic Diseases
2011
An update on the role of human dendritic cells in patients with atopic dermatitis
2012
Thymic stromal lymphopoietin and allergic disease
2012
LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs
2011
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense
2009
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Role of Bacterial Superantigens in Atopic Dermatitis
2006
Itching for Insight
2009 StandoutNobel
Skin barrier in atopic dermatitis
2014
The bacterial superantigen and superantigen‐like proteins
2008
Innate immunity and antimicrobial defense systems in psoriasis
2007
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
2009
Cyclosporine in patients with atopic dermatitis modulates activated inflammatory pathways and reverses epidermal pathology
2014
Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis
2017
The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma
2014
Psoriasis
2021 Standout
Inflammatory bowel disease: cause and immunobiology
2007 Standout
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming
2009
Identification of novel gene signatures in patients with atopic dermatitis complicated by eczema herpeticum
2014
Mechanisms of allergen-specific immunotherapy
2011
Nonresolving Inflammation
2010 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Induction of allergic inflammation by interleukin‐18 in experimental animal models
2004
Exposure to Environmental Microorganisms and Childhood Asthma
2011 Standout
Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus
2010
The skin microbiome
2011 Standout
Expression of the antimicrobial peptide α-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10-deficient mice
2010
Psoriasis
2015 Standout
Defensin‐related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6
2009 StandoutNobel
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients
2007
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum
2009
Genetic Variants in Interferon Regulatory Factor 2 (IRF2) Are Associated with Atopic Dermatitis and Eczema Herpeticum
2011
Peeling off the genetics of atopic dermatitis–like congenital disorders
2014
Innate immune defects in atopic dermatitis
2006
The JAK/STAT signaling pathway: from bench to clinic
2021 Standout
The development of allergic inflammation
2008 StandoutNature
Constitutive Autophagy and Nucleophagy during Epidermal Differentiation
2016
Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis
2014
IL-31 regulates differentiation and filaggrin expression in human organotypic skin models
2011
Epidermal barrier formation and recovery in skin disorders
2006
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Defensins in innate antiviral immunity
2006
Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore–induced allergic airway disease
2010
Variants in a Novel Epidermal Collagen Gene (COL29A1) Are Associated with Atopic Dermatitis
2007
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities
2011
Cellular Genomic Maps Help Dissect Pathology in Human Skin Disease
2007
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization
2015
Psoriasis: dysregulation of innate immunity
2005
The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila
2008 StandoutNobel
Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
2011
Immune surveillance in the skin: mechanisms and clinical consequences
2004
IL-33 and ST2 in Atopic Dermatitis: Expression Profiles and Modulation by Triggering Factors
2012
Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3
2008 StandoutNobel
IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells
2009
Immunopathogenesis of Psoriasis
2007
In Vitro Assessment of IL-4- or IL-13-Mediated Changes in the Structural Components of Keratinocytes in Mice and Humans
2013
Selective JAK1 Inhibitors for the Treatment of Atopic Dermatitis: Focus on Upadacitinib and Abrocitinib
2020
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens
2009
β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice
2009 StandoutNobel
Animal Models of Atopic Dermatitis
2008
Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis
2019
Screening for key genes associated with atopic dermatitis with DNA microarrays
2014
Possible new therapeutic strategy to regulate atopic dermatitis through upregulating filaggrin expression
2013
Stratum Corneum Defensive Functions: An Integrated View
2005
Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis
2006
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march
2006
Multiple microbial exposures in the home may protect against asthma or allergy in childhood
2010
Molecular Dissection of Psoriasis: Integrating Genetics and Biology
2009
High Expression Levels of Keratinocyte Antimicrobial Proteins in Psoriasis Compared with Atopic Dermatitis
2005
Distinct patterns of gene expression in the skin lesions of atopic dermatitis and psoriasis
2003
Immunomodulatory Properties of Defensins and Cathelicidins
2006
Therapeutic modulators of STAT signalling for human diseases
2013
Human Cathelicidin (LL-37), a Multifunctional Peptide, is Expressed by Ocular Surface Epithelia and has Potent Antibacterial and Antiviral Activity
2005
New perspectives on epidermal barrier dysfunction in atopic dermatitis: Gene–environment interactions
2006
Nicotinic Acid-Induced Flushing Is Mediated by Activation of Epidermal Langerhans Cells
2006
Differential Gene Induction of Human β-Defensins (hBD-1, -2, -3, and -4) in Keratinocytes Is Inhibited by Retinoic Acid
2004
Cytokine-mediated regulation of antimicrobial proteins
2008
Staphylococcus epidermidis Antimicrobial δ-Toxin (Phenol-Soluble Modulin-γ) Cooperates with Host Antimicrobial Peptides to Kill Group A Streptococcus
2010
Cathelicidin deficiency predisposes to eczema herpeticum
2006
Mammalian defensins in the antimicrobial immune response
2005 Standout
Neuroimmune interactions in allergic skin diseases
2007
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Primate defensins
2004
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy
2007
Antimicrobial Peptides: An Essential Component of the Skin Defensive Barrier
2006
Type‐IV sensitization profile of individuals with atopic eczema: results from the Information Network of Departments of Dermatology (IVDK) and the German Contact Dermatitis Research Group (DKG)
2006
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity
2010 StandoutNobel
Expression of antimicrobial peptides in atopic dermatitis and possible immunoregulatory functions
2013
A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1
2013
Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients
2012
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency
2012
Biological Therapies for Atopic Dermatitis: A Systematic Review
2021
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Treatment Outcomes of Secondarily Impetiginized Pediatric Atopic Dermatitis Lesions and the Role of Oral Antibiotics
2011
The neurobiology of itch
2006
The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis
2005
Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice
2006
Modulation of the TLR-Mediated Inflammatory Response by the Endogenous Human Host Defense Peptide LL-37
2006
Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses
2008 StandoutNobel
Mammalian defensins: structures and mechanism of antibiotic activity
2004
Homeostasis of Thymus-Derived Foxp3+ Regulatory T Cells Is Controlled by Ultraviolet B Exposure in the Skin
2014 StandoutNobel
Triggering psoriasis: the role of infections and medications
2007
Induction of the human cathelicidin LL-37 as a novel treatment against bacterial infections
2012
Ultraviolet B–Induced Maturation of CD11b-Type Langerin− Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin
2017 StandoutNobel
Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells
2010
TRPA1-Dependent Pruritus in IL-13–Induced Chronic Atopic Dermatitis
2013
Multiple Sclerosis
2018 Standout
A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease
2020
Machine Learning in Medicine
2019 Standout
Application of Janus Kinase Inhibitors in Atopic Dermatitis: An Updated Systematic Review and Meta-Analysis of Clinical Trials
2021
The Role of Histamine H1 and H4 Receptors in Atopic Dermatitis: From Basic Research to Clinical Study
2014
Metagenomics of the Human Body
2010
Reduced filaggrin expression is accompanied by increased Staphylococcus aureus colonization of epidermal skin models
2014
Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins
2005
Distinct Entry Mechanisms for Nonenveloped and Quasi-Enveloped Hepatitis E Viruses
2016
Differential Regulation of β-Defensin Expression in Human Skin by Microbial Stimuli
2005
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Ionizing Radiation Selectively Reduces Skin Regulatory T Cells and Alters Immune Function
2014 StandoutNobel
Cellular and molecular mechanisms in the hypoxic tissue: role of HIF‐1 and ROS
2013
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Solution Structures of Human LL-37 Fragments and NMR-Based Identification of a Minimal Membrane-Targeting Antimicrobial and Anticancer Region
2006
Antimicrobial proteins and peptides: anti-infective molecules of mammalian leukocytes
2004
CC Chemokine Ligand 18, An Atopic Dermatitis-Associated and Dendritic Cell-Derived Chemokine, Is Regulated by Staphylococcal Products and Allergen Exposure
2004
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
What have we learned in dermatology from the biologic therapies?
2006
Deficiency of Dermcidin-Derived Antimicrobial Peptides in Sweat of Patients with Atopic Dermatitis Correlates with an Impaired Innate Defense of Human Skin In Vivo
2005
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy
2007
Works of Michael Howell being referenced
IL-4 Regulates Skin Homeostasis and the Predisposition toward Allergic Skin Inflammation
2010
Treatment of atopic dermatitis with ruxolitinib cream (JAK1/JAK2 inhibitor) or triamcinolone cream
2019
Targeting the Janus Kinase Family in Autoimmune Skin Diseases
2019
Specificity protein 1 is pivotal in the skin’s antiviral response
2011
Immunomodulatory effect of endotoxin on the development of latex allergy☆
2004
Vaccinia virus–specific molecular signature in atopic dermatitis skin
2010
Ruxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial
2020
The Constitutive Capacity of Human Keratinocytes to Kill Staphylococcus aureus Is Dependent on β-Defensin 3
2007
TNF-α Downregulates Filaggrin and Loricrin through c-Jun N-terminal Kinase: Role for TNF-α Antagonists to Improve Skin Barrier
2011
Mechanism of HBD-3 deficiency in atopic dermatitis
2006
A PROSPECTIVE, OBSERVATIONAL STUDY OF SOLUBLE FLT-1 AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN SEPSIS
2008
Cytokine modulation of atopic dermatitis filaggrin skin expression
2007
Treatment of atopic dermatitis with tralokinumab, an anti–IL-13 mAb
2018
IL-31 is associated with cutaneous lymphocyte antigen–positive skin homing T cells in patients with atopic dermatitis
2006
Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6
2008
JAK/STAT inhibitors and other small molecule cytokine antagonists for the treatment of allergic disease
2018
New insights into atopic dermatitis
2004
Cytokine modulation of atopic dermatitis filaggrin skin expression
2009
Macrophage inflammatory protein 3α deficiency in atopic dermatitis skin and role in innate immune response to vaccinia virus
2006
Acid Suppression Therapy Does Not Predispose to Clostridium difficile Infection: The Case of the Potential Bias
2014
Th2 Cytokines Act on S100/A11 to Downregulate Keratinocyte Differentiation
2008
Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response
2011
Interleukin-10 Downregulates Anti-Microbial Peptide Expression in Atopic Dermatitis
2005
Cytokine Milieu of Atopic Dermatitis Skin Subverts the Innate Immune Response to Vaccinia Virus
2006
T cell repertoire following autologous stem cell transplantation for multiple sclerosis
2014
Ensuring Fairness in Machine Learning to Advance Health Equity
2018 Standout
IL-4 and IL-13 Negatively Regulate TNF-α- and IFN-γ-Induced β-Defensin Expression through STAT-6, Suppressor of Cytokine Signaling (SOCS)-1, and SOCS-3
2007
New insights into atopic dermatitis
2004
Selective Killing of Vaccinia Virus by LL-37: Implications for Eczema Vaccinatum
2004
Ruxolitinib for the treatment of steroid-refractory acute GVHD (REACH1): a multicenter, open-label phase 2 trial
2020
Cytokine Milieu of Atopic Dermatitis, as Compared to Psoriasis, Skin Prevents Induction of Innate Immune Response Genes
2003
Past, present, and future for biologic intervention in atopic dermatitis
2015
Structure-Function Relationships among Human Cathelicidin Peptides: Dissociation of Antimicrobial Properties from Host Immunostimulatory Activities
2005