Citation Impact
Citing Papers
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: A tool for efficient genetic engineering of mammalian genomes
2002
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
2007 Standout
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Tissue plasminogen activator is a potent activator of PDGF‐CC
2004
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
The Lipoprotein Receptor LR11 Regulates Amyloid β Production and Amyloid Precursor Protein Traffic in Endosomal Compartments
2006
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
2011
α-Synuclein Protects against Oxidative Stress via Inactivation of the c-Jun N-terminal Kinase Stress-signaling Pathway in Neuronal Cells
2002
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
The sorLA cytoplasmic domain interacts with GGA1 and ‐2 and defines minimum requirements for GGA binding
2001
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
Inflammation and metabolic disorders
2006 StandoutNature
PDGF signaling in cells and mice
2004
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Essential roles for the FE65 amyloid precursor protein‐interacting proteins in brain development
2006
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Intrinsic disorder in scaffold proteins: Getting more from less
2008
LRP: a multifunctional scavenger and signaling receptor
2001
Abdominal aortic aneurysm
2005 Standout
Lipoprotein receptors and a Disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans
2003
The Adaptor Protein β-Arrestin2 Enhances Endocytosis of the Low Density Lipoprotein Receptor
2003
The roles of cubilin and megalin, two multiligand receptors, in proximal tubule function: possible implication in the progression of renal disease
2001
Regulated portals of entry into the cell
2003 StandoutNature
Polycystin-1 and -2 Dosage Regulates Pressure Sensing
2009
Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family
2006 StandoutNobel
Low‐density lipoprotein receptor‐related protein levels and endocytic function are reduced by overexpression of the FE65 adaptor protein, FE65L1
2002
Assignment of the gene encoding renin binding protein <i>(Renbp)</i> to rat chromosome Xq37 by in situ hybridization and radiation hybrid mapping
2002
Expression of Tumor Necrosis Factor Receptor-1 in Arterial Wall Cells Promotes Atherosclerosis
2007
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Platelet-derived Growth Factor (PDGF)-induced Tyrosine Phosphorylation of the Low Density Lipoprotein Receptor-related Protein (LRP)
2002
Disabled‐2 Colocalizes with the LDLR in Clathrin‐Coated Pits and Interacts with AP‐2
2001
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
2004
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Regulation of the Platelet-derived Growth Factor Receptor-β by G Protein-coupled Receptor Kinase-5 in Vascular Smooth Muscle Cells Involves the Phosphatase Shp2
2006
Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor
2002
Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair.
2001
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
The Platelet-derived Growth Factor Receptor-β Phosphorylates and Activates G Protein-coupled Receptor Kinase-2
2005
Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice
2000
Platelet-derived Growth Factor Receptor-β (PDGFR-β) Activation Promotes Its Association with the Low Density Lipoprotein Receptor-related Protein (LRP)
2005
Tbr1 Regulates Differentiation of the Preplate and Layer 6
2001
Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons
2004
Additive Effects of PDGF Receptor β Signaling Pathways in Vascular Smooth Muscle Cell Development
2003
Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth
2009
GlcNAc 2-Epimerase Can Serve a Catabolic Role in Sialic Acid Metabolism
2003 StandoutNobel
Extracellular Matrix: Functions in the Nervous System
2010
Expression profiling of epithelial plasticity in tumor progression
2003
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
The Role of Apolipoprotein E in Alzheimer's Disease
2009
Physiology of Local Renin-Angiotensin Systems
2006 Standout
Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated
2010
PDGF and cardiovascular disease
2004
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Retromer disruption promotes amyloidogenic APP processing
2011
A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
2013 Standout
LRP1 Functions as an Atheroprotective Integrator of TGFβ and PDGF Signals in the Vascular Wall: Implications for Marfan Syndrome
2007
Insulin resistance and atherosclerosis
2006
Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Controls Endocytosis and c-CBL-mediated Ubiquitination of the Platelet-derived Growth Factor Receptor β (PDGFRβ)
2005
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Physiological Relevance of Renin/Prorenin Binding and Uptake
2005
The YXXL Motif, but Not the Two NPXY Motifs, Serves as the Dominant Endocytosis Signal for Low Density Lipoprotein Receptor-related Protein
2000
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Regulation of the Ligand Binding Activity of the Human Very Low Density Lipoprotein Receptor by Protein Kinase C-dependent Phosphorylation
2001
The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier Aβ Clearance in Alzheimers Disease
2008
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research
2001
Retromer
2008
Prorenin Uptake in the Heart: a Prerequisite for Local Angiotensin Generation?
2002
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing
2012
Molecular mechanisms of apolipoprotein B mRNA editing
2001
Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1
2007
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Impaired Cytokine Signaling in Mice Lacking the IL-1 Receptor-Associated Kinase
1999
Lipoprotein Receptors in the Nervous System
2002
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Huxleys’ Missing Filament: Form and Function of Titin in Vertebrate Striated Muscle
2016
Serpin Structure, Mechanism, and Function
2002 Standout
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Expression of Tumor Necrosis Factor Receptor-1 in Arterial Wall Cells Promotes Atherosclerosis
2007
A chemical approach for identifying O -GlcNAc-modified proteins in cells
2003 StandoutNobel
Essential Role of Developmentally Activated Hypoxia-Inducible Factor 1α for Cardiac Morphogenesis and Function
2008
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Roles of PDGF in animal development
2003
THE ENGULFMENT PROCESS OF PROGRAMMED CELL DEATH INCAENORHABDITIS ELEGANS
2004 Nobel
Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene
2001 Nobel
RIM genes differentially contribute to organizing presynaptic release sites
2012 StandoutNobel
Autosomal Recessive Hypercholesterolemia Caused by Mutations in a Putative LDL Receptor Adaptor Protein
2001 Science
Pulmonary Arterial Hypertension Is Linked to Insulin Resistance and Reversed by Peroxisome Proliferator–Activated Receptor-γ Activation
2007
Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein
1998
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
LRP: a multifunctional scavenger and signaling receptor
2001
Conditional Disruption of the Aryl Hydrocarbon Receptor Nuclear Translocator (Arnt) Gene Leads to Loss of Target Gene Induction by the Aryl Hydrocarbon Receptor and Hypoxia-Inducible Factor 1α
2000
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning
2008 StandoutNobel
β-Arrestins Regulate Atherosclerosis and Neointimal Hyperplasia by Controlling Smooth Muscle Cell Proliferation and Migration
2008 StandoutNobel
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
2004 StandoutNobel
Works of Michael Gotthardt being referenced
Calcium sensitivity and the Frank–Starling mechanism of the heart are increased in titin N2B region-deficient mice
2010
The Reelin Receptor ApoER2 Recruits JNK-interacting Proteins-1 and -2
2000
Cellular signalling by lipoprotein receptors
2000
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.
1998
Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2
1999
Sustained somatic gene inactivation by viral transfer of Cre recombinase
1996
Interactions of the Low Density Lipoprotein Receptor Gene Family with Cytosolic Adaptor and Scaffold Proteins Suggest Diverse Biological Functions in Cellular Communication and Signal Transduction
2000
Platelet-derived Growth Factor Mediates Tyrosine Phosphorylation of the Cytoplasmic Domain of the Low Density Lipoprotein Receptor-related Protein in Caveolae
2002
Enhancement of the endothelial NO synthase attenuates experimental diastolic heart failure
2009
Normal Blood Pressure and Plasma Renin Activity in Mice Lacking the Renin-binding Protein, a Cellular Renin Inhibitor
2000
Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure
2002
Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy
2007
The Complete Gene Sequence of Titin, Expression of an Unusual ≈700-kDa Titin Isoform, and Its Interaction With Obscurin Identify a Novel Z-Line to I-Band Linking System
2001
M line–deficient titin causes cardiac lethality through impaired maturation of the sarcomere
2006
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
2005
LRP: Role in Vascular Wall Integrity and Protection from Atherosclerosis
2003 Science