Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Autonomic Nerve Development Contributes to Prostate Cancer Progression
2013 StandoutScience
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Role of Calcitonin Gene-Related Peptide in Light-Aversive Behavior: Implications for Migraine
2009
Characterization and Regulation of Angiotensin II Receptors in Rat Adipose Tissue
1996
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
2006 StandoutNobel
Delayed Upregulation of ATP P2X3 Receptors of Trigeminal Sensory Neurons by Calcitonin Gene-Related Peptide
2006
The Nonpeptide Calcitonin Gene-Related Peptide Receptor Antagonist BIBN4096BS Lowers the Activity of Neurons with Meningeal Input in the Rat Spinal Trigeminal Nucleus
2005
Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
2009 StandoutNobel
Inhibitory effect of BIBN4096BS on cephalic vasodilatation induced by CGRP or transcranial electrical stimulation in the rat
2004
β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation
2002 StandoutNobel
Angiotensin Receptors and Their Antagonists
1996
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor
1998
Fluorescent Labeling of Purified β2 Adrenergic Receptor
1995 StandoutNobel
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
2016
Identification of adrenomedullin receptors in cultured rat astrocytes and in neuroblastboma × glioma hybrid cells (NG108-15)
1996
Blockade and reversal of spinal morphine tolerance by peptide and non‐peptide calcitonin gene‐related peptide receptor antagonists
2000
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Marine natural products
1990 Standout
Hallmarks of aging: An expanding universe
2023 Standout
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Muscarinic Receptors—Characterization, coupling and function
1993
Radioiodinated CGP 42111A: A novel high affinity and highly selective ligand for the characterization of angiotensin AT2 receptors
1991
Effect of human adrenomedullin on a canine tibial perfusion model in the absence of vascular endothelium
1996
Regulation of Neuropeptide Y Release by Neuropeptide Y Receptor Ligands and Calcium Channel Antagonists in Hypothalamic Slices
1999
The ligand binding site of the angiotensin AT1 receptor
1996
A receptor subtype involved in neuropeptide-Y-induced food intake
1996 Nature
Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice
2008
Asymmetric spiroacetalization catalysed by confined Brønsted acids
2012 StandoutNatureNobel
Modulation of nocioceptive transmission with calcitonin gene-related peptide receptor antagonists in the thalamus
2010
Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator
2008
The NPY system in stress, anxiety and depression
2004
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine
2004 Standout
Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment
2002
Marine Natural Products as Prototype Agrochemical Agents
2003
Neuroanatomical Localization, Pharmacological Characterization and Functions of CGRP, Related Peptides and Their Receptors
1997
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Calcitonin gene‐related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat
2004
The Catalytic Asymmetric Acetalization
2013 StandoutNobel
GITR subverts Foxp3+ Tregs to boost Th9 immunity through regulation of histone acetylation
2015
Migraine — Current Understanding and Treatment
2002 Standout
A role for ghrelin in the central regulation of feeding
2001 StandoutNature
Cell Wall Active Antifungal Compounds Produced by the Marine Fungus Hypoxylon oceanicum LL-15G256. II. Isolation and Structure Determination.
1998
Role of hypothalamic neuropeptide Y in feeding and obesity
1999
Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding
1999
The receptor activity modifying protein family of G protein coupled receptor accessory proteins
2004
A review of mutagenesis studies of angiotensin II type 1 receptor, the three-dimensional receptor model in search of the agonist and antagonist binding site and the hypothesis of a receptor activation mechanism
1997
GPCR modulation by RAMPs
2005
Physiology of Local Renin-Angiotensin Systems
2006 Standout
How Chemoproteomics Can Enable Drug Discovery and Development
2012
The pharmacology of CGRP-responsive receptors in cultured and transfected cells
2004
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Obesity and the Regulation of Energy Balance
2001 Standout
The angiotensin hexapeptide 3–8 fragment potently inhibits [125I]angiotensin II binding to non-AT1 or -AT2 recognition sites in bovine adrenal cortex
1992
The Hallmarks of Aging
2013 Standout
Biogenetic Diversity of Cyanobacterial Metabolites
2007
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Subtype selectivity of the novel nonpeptide neuropeptide Y Y1 receptor antagonist BIBO 3304 and its effect on feeding in rodents
1998
Diencephalic and brainstem mechanisms in migraine
2011
Dependence of AT1 Angiotensin Receptor Function on Adjacent Asparagine Residues in the Seventh Transmembrane Helix
1998
Receptor Activity-modifying Proteins 2 and 3 Have Distinct Physiological Functions from Embryogenesis to Old Age
2007 StandoutNobel
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Can a Ketone Be More Reactive than an Aldehyde? Catalytic Asymmetric Synthesis of Substituted Tetrahydrofurans
2018 StandoutNobel
Structurally diverse new alkaloids from Palauan collections of the apratoxin-producing marine cyanobacterium Lyngbya sp.
2002
Immunohistochemical Localization of Calcitonin Receptor–Like Receptor and Receptor Activity–Modifying Proteins in the Human Cerebral Vasculature
2002
High-affinity neuropeptide Y receptor antagonists.
1995
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors.
1994
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS, the First Selective Small Molecule Calcitonin Gene-Related Peptide Receptor Antagonist, Following Single Intravenous Administration in Healthy Volunteers
2004
Isolation and Structure Assignment of an Iminotetrasaccharide from a Cultured Filamentous CyanobacteriumAnabaenasp.
2006
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Adrenomedullin: A Possible Autocrine or Paracrine Inhibitor of Hypertrophy of Cardiomyocytes
1998
Grenadadiene and Grenadamide, Cyclopropyl-Containing Fatty Acid Metabolites from the Marine Cyanobacterium Lyngbya majuscula
1998
Nonanomeric Spiroketals in Natural Products: Structures, Sources, and Synthetic Strategies
2005
Total Synthesis of Oxacyclic Macrodiolide Natural Products
2005
The Role of Natural Product Chemistry in Drug Discovery
2004
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Microwave-Assisted C−H Bond Activation: A Rapid Entry into Functionalized Heterocycles
2003
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Molluscicidal Metabolites from an Assemblage of Palmyra Atoll Cyanobacteria
2011
Enantioselective Synthesis of the R-Enantiomer of the Feeding Deterrent (S)-Ypaoamide
2009
Sirtuins, a key regulator of ageing and age-related neurodegenerative diseases
2022
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
Regioselective synthesis of the 1-bromo-4-phenyl-tetrahydro-7-amino-benzocyclohepten-6-one, a subnanomolar aminopeptidase-N/CD13 inhibitor
2012
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothelial cells and induce its desensitisation by different mechanisms
2006
Identification of functional angiotensin II receptors on rat cardiac fibroblasts.
1993
Total syntheses of oscillatoxin D and 30-methyloscillatoxin D
1995
Involvement of Neuropeptide Y Y1 Receptors in the Regulation of Neuroendocrine Corticotropin-Releasing Hormone Neuronal Activity
2007
Mammalian Sirtuins: Biological Insights and Disease Relevance
2010 Standout
The CGRP-Antagonist, BIBN4096BS Does not Affect Cerebral or Systemic Haemodynamics in Healthy Volunteers
2005
Octreotide is not Effective in the Acute Treatment of Migraine
2004
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
MOLECULAR MECHANISM OF 7TM RECEPTOR ACTIVATION—A GLOBAL TOGGLE SWITCH MODEL
2006
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Efficient, simple procedures for the large‐scale preparation of building blocks for angiotensin (II) receptor antagonists
1995
Vascular Actions of Calcitonin Gene-Related Peptide and Adrenomedullin
2004
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
IDPi Catalysis
2019 StandoutNobel
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
Adrenomedullin, a Multifunctional Regulatory Peptide*
2000
Catalytic Annulation of Heterocycles via a Novel Redox Process Involving the Imidazolium Salt N-Heterocyclic Carbene Couple
2008
Syntheses of piperidine and perhydroazepine derivatives, precursors of two selective antagonists of muscarinic M2 receptors: AF-DX 384 and its perhydroazepine isomer
1996
Catalytic Asymmetric Transacetalization
2010 StandoutNobel
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Enhanced Vascular Responses to Adrenomedullin in Mice Overexpressing Receptor-Activity–Modifying Protein 2
2005
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Adrenomedullin: Potential in physiology and pathophysiology
2000
Receptor Activity-Modifying Proteins: RAMPing up Adrenomedullin Signaling
2006
Chemical Glycoproteomics
2016 StandoutNobel
Calcitonin Gene-Related Peptide: Physiology and Pathophysiology
2014
Cgrp May Play A Causative Role in Migraine
2002 Standout
Works of Michael Entzeroth being referenced
Pharmacological characterization of the selective nonpeptide neuropeptide Y Y1 receptor antagonist BIBP 3226.
1995
Mutations in transmembrane segment VIJ of the AT1 receptor differentiate between closely related insurmountable and competitive angiotensin antagonists
1994
Characterization of rat intestinal anglotensin II receptors
1991
The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226
1994
Adrenomedullin mediates vasodilation via CGRP1 receptors
1994
BIBP 3226, the first selective neuropeptide Y1 receptor antagonist: A review of its pharmacological properties
1996
Characterization of porcine coronary muscarinic receptors
1990
6-Substituted benzimidazoles as new nonpeptide angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships
1993
SIRT1 Modulating Compounds from High-Throughput Screening as Anti-Inflammatory and Insulin-Sensitizing Agents
2006
Emerging trends in high-throughput screening
2003
Angiotensin II receptors in the rat lung are of the AII-1 subtype
1991
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
2000
Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277
1993
Characterization of BIBS 39 and BIBS 222: two new nonpeptide angiotensin II receptor antagonists
1992
Labeling of neuropeptide Y receptors in SK-N-MC cells using the novel, nonpeptide Y1 receptor-selective antagonist [3H]BIBP3226
1995
High throughput drug profiling
2000
Labeling of rat heart muscarinic receptors using the new M2 selective antagonist [3H]AF-DX 384
1990
Function of the SIRT1 protein deacetylase in cancer
2007
O-Acetyl-O-butyryl-O-carbamoyl-O,O-dimethyl-.alpha.-cyclodextrins from the cyanophyte Tolypothrix byssoidea
1986
Majusculamide D and deoxymajusculamide D, two cytotoxins from Lyngbya majuscula
1988
Different types of receptor interaction of peptide and nonpeptide angiotensin II antagonists revealed by receptor binding and functional studies.
1992
Development of Human Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonists. 1. Potent and Selective Small Molecule CGRP Antagonists. 1-[N2-[3,5-Dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1- piperidinyl]carbonyl]-d -tyrosyl]-l -lysyl]-4-(4-pyridinyl)piperazine: The First CGRP Antagonist for Clinical Trials in Acute Migraine
2005
Subtype selectivity and antagonistic profile of the nonpeptide Y1 receptor antagonist BIBP 3226.
1995
Binding studies of [H]Lyngbyatoxin A and [H]debromoaplysiatoxin to the phorbol ester receptor in a mouse epidermal particulate fraction
1986
A herbicidal fatty acid produced by Lyngbya aestuarii
1985
Structures and stereochemistries of oscillatoxin B, 31-noroscillatoxin B, oscillatoxin D, and 30-methyloscillatoxin D
1985