Citation Impact
Citing Papers
Activation of Drosophila Toll During Fungal Infection by a Blood Serine Protease
2002 StandoutScienceNobel
Feedback activation of factor XI by thrombin does not occur in plasma
2007
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
The Unconventional Secretory Machinery of Fibroblast Growth Factor 2
2011
Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex
2008
The role of phospholipid and factor VIIIa in the activation of bovine factor X.
1981
The Tissue Factor Requirement in Blood Coagulation
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
Platelets: Physiology and Biochemistry
2005
Mechanisms of Thrombus Formation
2008 Standout
Inflammation and cancer
2002 StandoutNature
Oxidized Phospholipids Are Present on Plasminogen, Affect Fibrinolysis, and Increase Following Acute Myocardial Infarction
2012
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Cloning of cDNAs coding for the heavy chain region and connecting region of human factor V, a blood coagulation factor with four types of internal repeats
1987
Additivity in Effects of Vitronectin and Monoclonal Antibodies against α-Helix F of Plasminogen Activator Inhibitor-1 on Its Reactions with Target Proteinases
2004
Mutational analysis of the Drosophila snake protease: an essential role for domains within the proenzyme polypeptide chain.
1994
Human umbilical vein endothelial cells express high affinity receptors for factor Xa
1997
Moojenactivase, a novel pro-coagulant PIIId metalloprotease isolated from Bothrops moojeni snake venom, activates coagulation factors II and X and induces tissue factor up-regulation in leukocytes
2015
The changing landscape of atherosclerosis
2021 StandoutNature
The molecular basis of blood coagulation
1988 Standout
The Biochemical Basis of Warfarin Therapy
1987
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
Enhancement of rabbit jugular vein thrombolysis by neutralization of factor XI. In vivo evidence for a role of factor XI as an anti-fibrinolytic factor.
1998
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
1997 StandoutNature
Regulation of Extrinsic Pathway Factor Xa Formation by Tissue Factor Pathway Inhibitor
1998
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Calcium-dependent structural changes in bovine blood coagulation factor Va and its subunits
1989
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition
1989
The coagulation cascade: initiation, maintenance, and regulation
1991 Standout
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Mutation in blood coagulation factor V associated with resistance to activated protein C
1994 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma
1991 Standout
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Localization of the gene encoding human Factor V to chromosome 1q21–25
1988
Extrahepatic Expression and Regulation of Protein C in the Mouse
1998
Molecular and Cellular Biology of Blood Coagulation
1992
Activation of human factor V by factor Xa and thrombin
1990
Activated protein C prevents multiple organ injury following extensive hepatectomy in cirrhotic rats
2000
Activated Protein C Reduces the Ischemia/Reperfusion-Induced Spinal Cord Injury in Rats by Inhibiting Neutrophil Activation
2000
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
2001 Standout
Points of control in inflammation
2002 StandoutNature
Annexin VI is required for budding of clathrin-coated pits
1992 StandoutNobel
Fibrinolysis, inflammation, and regulation of the plasminogen activating system
2007
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Intensive Insulin Therapy in Critically Ill Patients
2001 Standout
Effects of human soluble thrombomodulin on experimental glomerulonephritis
2002 StandoutNobel
The immunopathogenesis of sepsis
2002 StandoutNature
Effects of factor IX or factor XI deficiency on ferric chloride‐induced carotid artery occlusion in mice
2005
Molecular cloning and expression of human hepatocyte growth factor
1989 StandoutNature
The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation
1989
The complete cDNA sequence of bovine coagulation factor V.
1992
Activation of factor V during intrinsic and extrinsic coagulation. Inhibition by heparin, hirudin and d -Phe-Pro-Arg-Ch2Cl
1990
Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders
1988
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Tissue Engineering
1993 StandoutScience
Adult hemoglobins are synthesized in murine fetal hepatic erythropoietic cells
1983
Tissue factor activity in whole blood
2004
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
Binding of annexin V/placental anticoagulant protein I to platelets. Evidence for phosphatidylserine exposure in the procoagulant response of activated platelets.
1990
Advances in skin grafting and treatment of cutaneous wounds
2014 StandoutScience
Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice
2012
Complete cDNA and derived amino acid sequence of human factor V.
1987
Pro-Carboxypeptidase R is an Acute Phase Protein in the Mouse, Whereas Carboxypeptidase N Is Not
2000 StandoutNobel
Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells
2008
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology
1989 StandoutNature
A Novel Approach to Arterial Thrombolysis
1999
Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade
1987
Human genes encoding prothrombin and ceruloplasmin map to 11p11?q12 and 3q21?24, respectively
1987
Molecular defect of prothrombin Barcelona. Substitution of cysteine for arginine at residue 273.
1986
Anticoagulant Properties of the Vascular Endothelium
1997
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
The Vitamin K-dependent Carboxylase
2002
Guidelines for the Primary Prevention of Stroke
2014 Standout
Prothrombin requires two sequential metal-dependent conformational transitions to bind phospholipid. Conformation-specific antibodies directed against the phospholipid-binding site on prothrombin.
1986
An endothelial cell-dependent pathway of coagulation.
1985
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
1994 StandoutNobel
Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.
1986
Structure of human factor VIII
1984 Nature
Proteolysis of factor Va by factor Xa and activated protein C.
1987
Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor.
1986
Heparin cofactor II. Purification and properties of a heparin-dependent inhibitor of thrombin in human plasma.
1982
The factor IX phospholipid-binding site is required for calcium-dependent activation of factor IX by factor XIa.
1987
The interactions between inflammation and coagulation
2005
Thrombin-catalyzed activation of human coagulation factor V.
1982
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Engineering the proteolytic specificity of activated protein C improves its pharmacological properties
2003
Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.
1982
Characterization of an Extremely Large, Ligand-Induced Conformational Change in Plasminogen
1990 StandoutScienceNobel
Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin.
1986
Angiogenic Factors
1987 StandoutScience
Platelet membrane glycoprotein IIb-IIIa complex incorporated into phospholipid vesicles. Preparation and morphology.
1985
Coagulation and inflammation
2001
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency
2008
Expression of completely gamma-carboxylated recombinant human prothrombin.
1987
Calorimetric evaluation of the existence of separate domains in bovine prothrombin
1981
Characterization of an interaction between protein C and ceruloplasmin.
1990
Identification of the binding site for activated protein C on the light chain of factors V and VIII.
1990
Molecular Events that Control the Protein C Anticoagulant Pathway
1993
The profibrinolytic effect of activated protein C in clots formed from plasma is TAFI-dependent
1996
Protein S is required for bovine platelets to support activated protein C binding and activity.
1985
Regulation and functions of the protein C anticoagulant pathway.
1999
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Vitamin K and Energy Transduction: A Base Strength Amplification Mechanism
1995 Science
Formation of a calcium-binding site on bovine activated factor V following recombination of the isolated subunits.
1982
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Requirement of Vascular Integrin α v β 3 for Angiogenesis
1994 StandoutScience
Vitamin K-dependent carboxylation. A synthetic peptide based upon the gamma-carboxylation recognition site sequence of the prothrombin propeptide is an active substrate for the carboxylase in vitro.
1988
Tumors: Wounds That Do Not Heal
1986 Standout
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
Complete sequence of the bithorax complex of Drosophila.
1995 StandoutNobel
An ordered addition, essential activation model of the tissue factor pathway of coagulation: evidence for a conformational cage
1986
The Tissue Factor Pathway: How It Has Become a “Prima Ballerina”
1995
Natural anticoagulant mechanisms.
1984
Genes Expressed in Human Tumor Endothelium
2000 StandoutScience
The contributions of Ca2+, phospholipids and tissue-factor apoprotein to the activation of human blood-coagulation factor X by activated factor VII
1990
The Regulation of Natural Anticoagulant Pathways
1987 Science
Localization of the metal-induced conformational transition of bovine prothrombin.
1984
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane
1989
Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding
2013
Suppression of TNF-α-Induced Apoptosis by NF-κB
1996 StandoutScience
A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.
1986
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.
1987 Standout
Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity.
1986
Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule
1986
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Molecular Cloning and Partial Characterization of Rat Procarboxypeptidase R and Carboxypeptidase N
2000 StandoutNobel
Cultured bovine aortic endothelial cells promote activated protein C-protein S-mediated inactivation of factor Va.
1986
Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V
1984
Prothrombin Loading of Vascular Smooth Muscle Cell–Derived Exosomes Regulates Coagulation and Calcification
2017
Human Plasma Protein C
1979
Works of Michael E. Nesheim being referenced
Elements of the Primary Structure of Thrombomodulin Required for Efficient Thrombin-activable Fibrinolysis Inhibitor Activation
2000
Thrombin-mediated activation of factor XI results in a thrombin-activatable fibrinolysis inhibitor-dependent inhibition of fibrinolysis.
1997
TAFI, or Plasma Procarboxypeptidase B, Couples the Coagulation and Fibrinolytic Cascades through the Thrombin-Thrombomodulin Complex
1996
Purification and Characterization of TAFI, a Thrombin-activable Fibrinolysis Inhibitor
1995
Both Cellular and Soluble Forms of Thrombomodulin Inhibit Fibrinolysis by Potentiating the Activation of Thrombin-activable Fibrinolysis Inhibitor
1998
A Steady-state Template Model That Describes the Kinetics of Fibrin-stimulated [Glu1]- and [Lys78]Plasminogen Activation by Native tissue-type Plasminogen Activator and Variants That Lack Either the Finger or Kringle-2 Domain
1997
Role of mRNA transcript stability in modulation of expression of the gene encoding thrombin activable fibrinolysis inhibitor
2004
Differential Signaling of Cysteinyl Leukotrienes and a Novel Cysteinyl Leukotriene Receptor 2 (CysLT2) Agonist, N-Methyl-Leukotriene C4, in Calcium Reporter and β Arrestin Assays
2010
A Role for CCAAT/Enhancer-binding Protein in Hepatic Expression of Thrombin-activable Fibrinolysis Inhibitor
2002
A Study of the Mechanism of Inhibition of Fibrinolysis by Activated Thrombin-activable Fibrinolysis Inhibitor
1998
Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara
2006
Roles of Thermal Instability and Proteolytic Cleavage in Regulation of Activated Thrombin-activable Fibrinolysis Inhibitor
2000
Inhibition of Plasminogen Activation by Lipoprotein(a)
2003
Acute Phase Mediators Modulate Thrombin-activable Fibrinolysis Inhibitor (TAFI) Gene Expression in HepG2 Cells
2003
Platelet factor Xa receptor
1992
The Factor V Activation Paradox
2004
The kinetics and cofactor dependence of the two cleavages involved in prothrombin activation.
1983
“Clotspeed,” a mathematical simulation of the functional properties of prothrombinase.
1984
Thrombin induces endothelial cell-surface exposure of the plasminogen receptor annexin 2
2003
Solulin increases clot stability in whole blood from humans and dogs with hemophilia
2012
The binding of 35S-labeled recombinant factor VIII to activated and unactivated human platelets.
1988
Identification of a congenital dysthrombin, thrombin Quick.
1980
Assembly of the Prothrombinase Complex
1982
Antifibrinolytic Effect of Recombinant Apolipoprotein(a) in Vitro Is Primarily Due to Attenuation of tPA-Mediated Glu-Plasminogen Activation
1995
On the Existence of Platelet Receptors for Factor V(a) and Factor VIII(a)
1993
Thrombin, Thrombomodulin and TAFI in the Molecular Link Between Coagulation and Fibrinolysis
1997
Internal duplication and sequence homology in factors V and VIII.
1985
The prothrombinase-catalyzed activation of prothrombin proceeds through the intermediate meizothrombin in an ordered, sequential reaction.
1986
Isolation and characterization of single chain bovine factor V.
1979
Characterization of Factor V activation intermediates.
1984
The factor Xa-catalyzed activation of factor V.
1983
Interactions of a fluorescent active-site-directed inhibitor of thrombin: dansylarginine N-(3-ethyl-1,5-pentanediyl)amide
1979
Thrombin-catalyzed activation of single chain bovine factor V.
1979
Activation of human prothrombin by human prothrombinase. Influence of factor Va on the reaction mechanism.
1987
A rapid technique for the preparation of factor V deficient plasma
1979
Activation of protein C and its distribution between its inhibitors, protein C inhibitor, alpha 1-antitrypsin and alpha 2-macroglobulin, in patients with disseminated intravascular coagulation.
1993
Molecular weight of undegraded plasma factor V
1981
[21] Factor V
1981
The Suicide Substrate Reaction Between Plasminogen Activator Inhibitor 1 and Thrombin Is Regulated by the Cofactors Vitronectin and Heparin
1997
Isolation of functional human coagulation factor V by using a hybridoma antibody.
1981
The effect of activated protein C on fibrinolysis in cell-free plasma can be attributed specifically to attenuation of prothrombin activation.
1993
Proteolytic alterations of factor Va bound to platelets.
1983
Phospholipid-binding properties of bovine factor V and factor Va
1979
Assembly of the prothrombinase complex in the absence of prothrombin.
1981
The effect of plasma von Willebrand factor on the binding of human factor VIII to thrombin-activated human platelets.
1991
The kinetics of activation of normal and gamma-carboxyglutamic acid-deficient prothrombins.
1985
Characterization of the Gene Encoding Human TAFI (Thrombin-Activable Fibrinolysis Inhibitor; Plasma Procarboxypeptidase B)
1999
Cofactor dependence of factor Xa incorporation into the prothrombinase complex.
1981
Activation of Protein C and Its Distribution between Its Inhibitors, Protein C Inhibitor, α1-Antitrypsin and α2-Macroglobulin, in Patients with Disseminated intravascular Coagulation
1993
Coordinate binding of factor Va and factor Xa to the unstimulated platelet.
1981
Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins.
1984
Interaction of coagulation factor V and factor Va with platelets.
1979
The activated protein C-mediated enhancement of tissue-type plasminogen activator-induced fibrinolysis in a cell-free system.
1990
Studies of the capacity of factor Xa to protect factor Va from inactivation by activated protein C.
1982
The contribution of bovine Factor V and Factor Va to the activity of prothrombinase.
1979