Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Controlling hazardous chemicals in microreactors: Synthesis with iodine azide
2009
Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCβ
2003
Dearomatization Strategies in the Synthesis of Complex Natural Products
2011
Recent advancements on the use of 2-methyltetrahydrofuran in organometallic chemistry
2016
Synthesis of 5‐Substituted 1H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach
2010
Introducing Deep Eutectic Solvents to Polar Organometallic Chemistry: Chemoselective Addition of Organolithium and Grignard Reagents to Ketones in Air
2014
Diverse sp3 C−H functionalization through alcohol β-sulfonyloxylation
2015
The evolution of cancer research and drug discovery at Lilly Research Laboratories
2005
Industrial research: Drug companies must adopt green chemistry
2016 Nature
Nanoparticles as Recyclable Catalysts: The Frontier between Homogeneous and Heterogeneous Catalysis
2005 Standout
A Two‐Step Continuous‐Flow Synthesis of N‐(2‐Aminoethyl)acylamides through Ring‐Opening/Hydrogenation of Oxazolines
2011
The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry
2015
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
2002 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Taming Hazardous Chemistry in Flow: The Continuous Processing of Diazo and Diazonium Compounds
2014
Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
2015 Standout
A Catalytic Asymmetric 6 π Electrocyclization: Enantioselective Synthesis of 2‐Pyrazolines
2009 StandoutNobel
The Organocatalytic Asymmetric Prins Cyclization
2015 StandoutNobel
Flow Chemistry Meets Advanced Functional Materials
2014
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
2016 StandoutNobel
Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
2016
Asymmetric 1,3-Dipolar Cycloaddition Reactions
1998 Standout
Ionic-Liquid-Mediated Extraction and Separation Processes for Bioactive Compounds: Past, Present, and Future Trends
2017 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Asymmetric Propargylation/Allylation/Pauson−Khand Cyclization of a Planar Chiral Anisole Tricarbonylchromium Complex
1997
Iron Catalysis in Organic Synthesis
2015 Standout
Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals
2013
3d Transition Metals for C–H Activation
2018 Standout
The Golden Age of Transfer Hydrogenation
2015 Standout
Overcoming barriers to green chemistry in the pharmaceutical industry – the Green Aspiration Level™ concept
2014
Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
2015 StandoutNobel
Enantioselective Synthesis with Lithium/(−)‐Sparteine Carbanion Pairs
1997
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Asymmetric Synthesis of Hydrobenzofuranones via Desymmetrization of Cyclohexadienones Using the Intramolecular Stetter Reaction
2006
Development of a practical and sustainable strategy for the synthesis of ST1535 by an iron-catalyzed Kumada cross-coupling reaction
2014
trans-3,4-Disubstituted pyrrolidines by 1,3-dipolar cycloaddition: enantioselective approaches and their limitations
1999
Chemistry of Polyvalent Iodine
2008 Standout
Towards Sustainable C−H Functionalization Reactions: The Emerging Role of Bio‐Based Reaction Media
2018
The accelerated preparation of 1,4-dihydropyridines using microflow reactors
2014
The Use of Molecular Oxygen in Pharmaceutical Manufacturing: Is Flow the Way to Go?
2016
Metal-Stabilized Methylene Arenium and σ-Arenium Compounds: Synthesis, Structure, Reactivity, Charge Distribution, and Interconversion
1999
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
Bis- and Trisindolylmethanes (BIMs and TIMs)
2009 Standout
Hydroamination: Direct Addition of Amines to Alkenes and Alkynes
2008 Standout
Silver Acetate Catalysed Asymmetric1,3-Dipolar Cycloadditions of Imines and Chiral Acrylamides
2003
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Diverse secondary C(sp3)–H bond functionalization via site-selective trifluoroacetoxylation of aliphatic amines
2018
Methylene Arenium Cations via Quinone Methides and Xylylenes Stabilized by Metal Complexation
1998
Organocatalysis by N-Heterocyclic Carbenes
2007 Standout
Safe Generation and Synthetic Utilization of Hydrazoic Acid in a Continuous Flow Reactor
2012
Cyclometalated Phosphine-Based Pincer Complexes: Mechanistic Insight in Catalysis, Coordination, and Bond Activation
2003 Standout
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Accessing Drug Metabolites via Transition‐Metal Catalyzed C−H Oxidation: The Liver as Synthetic Inspiration
2016
Continuous-Flow Electrophilic Amination of Arenes and Schmidt Reaction of Carboxylic Acids Utilizing the Superacidic Trimethylsilyl Azide/Triflic Acid Reagent System
2016
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Nitrogen Donors in Organometallic Chemistry and Homogeneous Catalysis
1994
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Advancing the Mechanistic Understanding of an Enantioselective Palladium-Catalyzed Alkene Difunctionalization Reaction
2010
Discovery of the First Metallaquinone
2000
A Sequential Ugi Multicomponent/Cu-Catalyzed Azide–Alkyne Cycloaddition Approach for the Continuous Flow Generation of Cyclic Peptoids
2015
Transition Metal-Mediated Cycloaddition Reactions
1996 Standout
General Synthesis, First Crystal Structure, and Reactivity of Stable o-Quinone Methide Complexes of Cp*Ir
1998
Heterogeneous catalysis in continuous flow microreactors: A review of methods and applications
2017
Synthesis of 5‐Substituted 1H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach
2010
Biomass-derived solvents as effective media for cross-coupling reactions and C–H functionalization processes
2017
Metal-Stabilized Quinone and Thioquinone Methides
1997
Palladium(II)-Catalyzed Direct Alkenylation and Arylation of Arenes: Removable 2-Pyridylsulfinyl Group Assisted C–H Bond Activation
2011
Highly Enantioselective Ag(I)-Catalyzed [3 + 2] Cycloaddition of Azomethine Ylides
2002
Helicenes: Synthesis and Applications
2011 Standout
Continuous Flow Synthesis. A Pharma Perspective
2012
Using Continuous Processes to Increase Production
2012
Green and Sustainable Solvents in Chemical Processes
2018 Standout
Palladium-catalyzed enyne–yne [4+2] benzannulation as a new and general approach to polysubstituted benzenes
1999
Kinetic Resolution of Homoaldols via Catalytic Asymmetric Transacetalization
2010 StandoutNobel
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Comprehensive mass analysis for chemical processes, a case study on l -Dopa manufacture
2014
Assessing Process Mass Intensity and Waste via an aza-Baylis–Hillman Reaction
2015
Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers
2011
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Eco-friendly Suzuki–Miyaura coupling of arylboronic acids to aromatic ketones catalyzed by the oxime-palladacycle in biosolvent 2-MeTHF
2016
A novel Fe(II)/diaryl prolinol catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with alkenes
2010
Enantioselective Synthesis of Hydrobenzofuranones Using an Asymmetric Desymmetrizing Intramolecular Stetter Reaction of Cyclohexadienones
2007
Reduced Transition Metal Colloids: A Novel Family of Reusable Catalysts?
2002 Standout
CoIII‐Catalyzed Isonitrile Insertion/Acyl Group Migration Between C−H and N−H bonds of Arylamides
2018
Continuous flow azide formation: Optimization and scale-up
2010
Metal-Free Trifluoromethylation of Aromatic and Heteroaromatic Aldehydes and Ketones
2014
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Pharmaceutical Roundtable Study Demonstrates the Value of Continuous Manufacturing in the Design of Greener Processes
2013
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Stable o-Quinone Methide Complexes of Iridium: Synthesis, Structure, and Reversed Reactivity Imparted by Metal Complexation
2000
Applications of ortho-Quinone Methide Intermediates in Catalysis and Asymmetric Synthesis
2011
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Construction of Enantiopure Pyrrolidine Ring System via Asymmetric [3+2]-Cycloaddition of Azomethine Ylides
2006 Standout
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
Catalytic Asymmetric Intramolecular [4+2] Cycloaddition of In Situ Generated ortho‐Quinone Methides
2017 StandoutNobel
Silver acetate-catalysed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides
2005
The Activation of Aromatic Molecules with Pentaammineosmium(II)
1997
Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions
2011 Standout
Taming Reactive Phenol Tautomers and o-Quinone Methides with Transition Metals: A Structure−Reactivity Relationship
2002
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
A biomass-derived safe medium to replace toxic dipolar solvents and access cleaner Heck coupling reactions
2014
Cross-dehydrogenative coupling reaction using copper oxide impregnated on magnetite in deep eutectic solvents
2015
Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions
2006 Standout
Visible Light Photocatalysis: Applications and New Disconnections in the Synthesis of Pharmaceutical Agents
2016
Quasi-Homogeneous Photocatalysis in Ultrastiff Microporous Polymer Aerogels
2024 StandoutNobel
Asymmetric Transition Metal-Catalyzed Allylic Alkylations
1996 Standout
Metal-Mediated Generation, Stabilization, and Controlled Release of a Biologically Relevant, Simple Para Quinone Methide: BHT-QM
1998
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
2013
2-Alkoxyarenol-derived orthoquinols in carbon–oxygen, carbon–nitrogen and carbon–carbon bond-forming reactions
2001
A base-free, ultrasound accelerated one-pot synthesis of 2-sulfonylquinolines in water
2017
An efficient synthesis of rufinamide, an antiepileptic drug
2010
Works of Michael E. Kopach being referenced
Operation Strategy Development for Grignard Reaction in a Continuous Stirred Tank Reactor
2015
Novel Michael Additions to Phenols Promoted by Osmium(II): Convenient Stereoselective Syntheses of 2,4- and 2,5-Cyclohexadienones
1994
Green Chemistry Approach to the Synthesis of N-Substituted Piperidones
2003
Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions
2013
Metalation−Alkylation of N-Activated Pyrrolidines. Rigorous Proof of Retention for Both Steps
1996
Activation of Benzylic Carbons in η2-Arene Complexes: A Novel and Efficient Synthesis of Functionalized Decalins
1998
Improved Synthesis of 1-(Azidomethyl)-3,5-bis-(trifluoromethyl)benzene: Development of Batch and Microflow Azide Processes
2009
Use Of The Electronic Laboratory Notebook To Facilitate Green Chemistry Within The Pharmaceutical Industry
2012
Phenol-cyclohexadienone equilibrium for .eta.2-coordinated arenes
1992
Osmium-Promoted Electrophilic Substitution of Anisoles: A Versatile New Method for the Incorporation of Carbon Substituents
1997
The continuous flow Barbier reaction: an improved environmental alternative to the Grignard reaction?
2012
Formation of o-Quinone Methides from η2-Coordinated Phenols and Their Controlled Release from a Transition Metal To Generate Chromans
2003
Green Chemical Synthesis of 2-Benzenesulfonyl-pyridine and Related Derivatives
2007
Direct 10.beta.-alkylation of .beta.-estradiol: osmium(II) as a dearomatization agent
1993
A deeper shade of green: inspiring sustainable drug manufacturing
2016
Seven Important Elements for an Effective Green Chemistry Program: An IQ Consortium Perspective
2013
Activation of Styrenes toward Diels−Alder Cycloadditions by Osmium(II): Synthesis of Stereodefined Decalin Ring Systems
1998
Protonation of Unactivated Aromatic Hydrocarbons on Osmium(II): Stabilization of Arenium Cations via Unprecedented η2- and η3-Coordination
1997
An Asymmetric Route to the Conanine BCDE Ring System. A Formal Total Synthesis of (+)-Conessine
1996
Sustainable Practices in Medicinal Chemistry: Current State and Future Directions
2013
The Osmium(II)-Promoted [4 + 2] Cycloaddition Reaction of Anisole and N-Methylmaleimide and Characterization of the .eta.2-4H-Anisolium Intermediate
1994
Stereodefined Tandem Addition Reactions of η2-Arenes: A Versatile Route to Functionalized Cyclohexenes
1998
Strategies for the synthesis of N-(azacycloalkyl)bisindolylmaleimides: selective inhibitors of PKCβ
2003
Practical Synthesis of Chiral 2-Morpholine: (4-Benzylmorpholin-2-(S)-yl)-(tetrahydropyran-4-yl)methanone Mesylate, a Useful Pharmaceutical Intermediate
2009
Electrophilic substitutions on .eta.2-coordinated arenes: an unprecedented Michael addition for phenol and aniline
1991