Standout Papers
Citation Impact
Citing Papers
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis
2017 StandoutNobel
Current and emerging systemic therapies for cutaneous metastatic melanoma
2019
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Discovery and engineering of enhanced SUMO protease enzymes
2018 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
2015 StandoutNobel
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
Engineering precision nanoparticles for drug delivery
2020 Standout
The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p
1999
Acromegaly
2006 Standout
Rapid Evolution Exposes the Boundaries of Domain Structure and Function in Natively Unfolded FG Nucleoporins
2006
Nuclear RNA export
1998 StandoutNobel
A Conserved mRNA Export Machinery Coupled to pre-mRNA Splicing
2002
Early Formation of mRNP
2003 StandoutNobel
A Block to mRNA Nuclear Export in S. cerevisiae Leads to Hyperadenylation of Transcripts that Accumulate at the Site of Transcription
2001 StandoutNobel
Molecular defects in the pathogenesis of pituitary tumours
2003
Smart cancer nanomedicine
2019
A Distinct Nuclear Import Pathway Used by Ribosomal Proteins
1997 StandoutNobel
Insight into Structure and Assembly of the Nuclear Pore Complex by Utilizing the Genome of a Eukaryotic Thermophile
2011
Quality control of mRNA 3′-end processing is linked to the nuclear exosome
2001 StandoutNatureNobel
From nucleoporins to nuclear pore complexes
1997
Two functionally distinct domains generated by invivo cleavage of Nup145p: a novel biogenesis pathway for nucleoporins
1997
Peering through the Pore
2003
Engineering interferons and interleukins for cancer immunotherapy
2022
Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p
1999
The yeast nucleoporin Rip1p contributes to multiple export pathways with no essential role for its FG-repeat region
1997 StandoutNobel
Tracking and Elucidating Alphavirus-Host Protein Interactions
2006 StandoutNobel
CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals
1997 Standout
Next generation of immune checkpoint therapy in cancer: new developments and challenges
2018
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
GTP Hydrolysis Links Initiation and Termination of Nuclear Import on the Nucleoporin Nup358
1999 StandoutNobel
Molecular Dissection of the Nuclear Pore Complex
1996
Global analysis of protein localization in budding yeast
2003 StandoutNature
The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88
1997
Gonad morphogenesis and distal tip cell migration in the Caenorhabditis elegans hermaphrodite
2012
3′‐end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation
2006 StandoutNobel
Yeast heat shock mRNAs are exported through a distinct pathway defined by Rip1p
1997
Proteomics to study genes and genomes
2000 StandoutNature
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human
1999
The importin-beta family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export
1997 StandoutNobel
Putative Reaction Intermediates in Crm1-mediated Nuclear Protein Export
1999 StandoutNobel
Cytokines in clinical cancer immunotherapy
2018
Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes
2004 StandoutNobel
Proteins Connecting the Nuclear Pore Complex with the Nuclear Interior
1999 StandoutNobel
Nucleocytoplasmic transport of macromolecules
1997
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
Small GTP-Binding Proteins
2001 Standout
Targeting and function in mRNA export of nuclear pore complex protein Nup153.
1996
Interactions between mRNA Export Commitment, 3′-End Quality Control, and Nuclear Degradation
2002 StandoutNobel
RanGTP-mediated nuclear export of karyopherin α involves its interaction with the nucleoporin Nup153
1997 StandoutNobel
Defining the essential functional regions of the nucleoporin Nup145p
1997
Two distinct classes of Ran-binding sites on the nucleoporin Nup-358
1999 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Nup84, A Novel Nucleoporin That Is Associated With CAN/Nup214 on the Cytoplasmic Face of the Nuclear Pore Complex
1997
A Novel Nuclear Import Pathway for the Transcription Factor TFIIS
1998 StandoutNobel
In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation.
1996
The yeast nucleoporin Nup188p interacts genetically and physically with the core structures of the nuclear pore complex.
1996 StandoutNobel
Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation
2020
A structure/function analysis of Rat7p/Nup159p, an essential nucleoporin of Saccharomyces cerevisiae
1997
Identification of Novel Saccharomyces cerevisiaeProteins with Nuclear Export Activity: Cell Cycle-Regulated Transcription Factor Ace2p Shows Cell Cycle-Independent Nucleocytoplasmic Shuttling
2000 StandoutNobel
C-Terminal Truncations of the Yeast Nucleoporin Nup145p Produce a Rapid Temperature-Conditional mRNA Export Defect and Alterations to Nuclear Structure
1997
Mass spectrometry-based proteomics
2003 StandoutNature
A Conserved Biogenesis Pathway for Nucleoporins: Proteolytic Processing of a 186-Kilodalton Precursor Generates Nup98 and the Novel Nucleoporin, Nup96
1999 StandoutNobel
The Yeast Nuclear Pore Complex
2000
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Nuclear Export of Heat Shock and Non-Heat-Shock mRNA Occurs via Similar Pathways
2000 StandoutNobel
Functional Characterization of a Nup159p-containing Nuclear Pore Subcomplex
1998
Arx1 Is a Nuclear Export Receptor for the 60S Ribosomal Subunit in Yeast
2007
The Karyopherin Kap122p/Pdr6p Imports Both Subunits of the Transcription Factor Iia into the Nucleus
1999 StandoutNobel
Autoproteolysis in nucleoporin biogenesis
1999 StandoutNobel
YEAST GENETICS TO DISSECT THE NUCLEAR PORE COMPLEX AND NUCLEOCYTOPLASMIC TRAFFICKING
1997
Nup120p: a yeast nucleoporin required for NPC distribution and mRNA transport.
1995 StandoutNobel
Binding of the Mex67p/Mtr2p Heterodimer to Fxfg, Glfg, and Fg Repeat Nucleoporins Is Essential for Nuclear mRNA Export
2000
A Nuclear Import Pathway for a Protein Involved in tRNA Maturation
1997 StandoutNobel
Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit
2010 StandoutNobel
A Distinct and Parallel Pathway for the Nuclear Import of an mRNA-binding Protein
1997 StandoutNobel
SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex
1998 StandoutNobel
Nuclear pore complex clustering and nuclear accumulation of poly(A)+ RNA associated with mutation of the Saccharomyces cerevisiae RAT2/NUP120 gene.
1995
Robust Distal Tip Cell Pathfinding in the Face of Temperature Stress Is Ensured by Two Conserved microRNAS inCaenorhabditis elegans
2015 StandoutNobel
Works of Michael E. Hurwitz being referenced
A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2Rβγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors
2019
Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans
2009 Nobel
Putative tumor-suppressor gene on chromosome 11 is important in sporadic endocrine tumor formation
1994
Effect of a novel IL-2 cytokine immune agonist (NKTR-214) on proliferating CD8+T cells and PD-1 expression on immune cells in the tumor microenvironment in patients with prior checkpoint therapy.
2017
NUP82 is an essential yeast nucleoporin required for poly(A)+ RNA export.
1995
A phase 1/2 study of a novel IL-2 cytokine, NKTR-214, and nivolumab in patients with select locally advanced or metastatic solid tumors.
2017
Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex
1998 StandoutNobel
Correction: Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans
2009 Nobel
NKTR-214 (CD122-biased agonist) plus nivolumab in patients with advanced solid tumors: Preliminary phase 1/2 results of PIVOT.
2018