Citation Impact
Citing Papers
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
Phylogenomic analyses support the monophyly of Excavata and resolve relationships among eukaryotic “supergroups”
2009 Standout
A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia
2013
Cytotoxicity and Induction of Proinflammatory Cytokines from Human Monocytes Exposed to Fine (PM2.5) and Coarse Particles (PM10–2.5) in Outdoor and Indoor Air
1999
Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis
2020 StandoutNobel
Drug Resistance in the Microaerophilic Parasite Giardia lamblia
2015
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Evaluation of Giardia lamblia thioredoxin reductase as drug activating enzyme and as drug target
2016
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
Allergenic relationship between taxonomically diverse pollens
1995
Atopic Dermatitis
2008 Standout
The three‐dimensional structure of porin from Rhodobacter capsulatus at 3 Å resolution
1990
Unique phylogenetic relationships of glucokinase and glucosephosphate isomerase of the amitochondriate eukaryotes Giardia intestinalis, Spironucleus barkhanus and Trichomonas vaginalis
2001
Molecular Characterization of Api g 1, the Major Allergen of Celery (Apium graveolens), and Its Immumological and Structural Relationships to a Group of 17‐kDa Tree Pollen Allergens
1995
Profilins as regulators of actin dynamics
1997
Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose
2008 Standout
Atopic dermatitis
2003 Standout
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
2001
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
2001 StandoutNature
Tobacco allergy: demonstration of cross-reactivity with other members of Solanaceae family and mugwort pollen
1999
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Melon sensitivity shares allergens with Plantago and grass pollens
1995
Kinetic Analysis of the Mechanism and Specificity of Protein-disulfide Isomerase Using Fluorescence-quenched Peptides
1998 StandoutNobel
Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia
2015
Antioxidant defence systems in the protozoan pathogen Giardia intestinalis
2015
Mutations at the 3′ splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast
1992
The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin
1997
Atopic dermatitis
2015 Standout
Early Formation of mRNP
2003 StandoutNobel
Basic and practical aspects of recombinant allergens
1995
Biological and Immunological Importance of BET v 1 Isoforms
1996
Ole e 3, An Olive‐Tree Allergen, Belongs to a Widespread Family of Pollen Proteins
1996
Proteomic and functional analyses reveal pleiotropic action of the anti-tumoral compound NBDHEX in Giardia duodenalis
2017
Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2)
2013
The major surface antigens of Entamoeba histolytica trophozoites are GPI-anchored proteophosphoglycans
2000
Interactions between inhalant allergen extracts and airway epithelial cells: Effect on cytokine production and cell detachment
1998
5′ exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly
2002
The immunopathogenesis of Entamoeba histolytica
2010
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
Profilin as a potential mediator of membrane-cytoskeleton communication
1993
Structural Basis of Inward Rectification
2002 StandoutNobel
Baculovirus vectors for multiple gene expression and for occluded virus production
1991
Reactions of macrophages exposed to particles <10μm
2003
Functional Characterization of Peroxiredoxins from the Human Protozoan Parasite Giardia intestinalis
2014
IgE reactivity to Api g 1, a major celery allergen, in a Central European population is based on primary sensitization by Bet v 1☆☆☆★
1999
Antisense oligonucleotides: towards clinical trials
1996
Autoimmunity and atopic dermatitis
2004
Exon mutations uncouple 5′ splice site selection from U1 snRNA pairing
1990 StandoutNobel
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
How far can we simplify in vitro diagnostics for grass pollen allergy?: A study with 17 whole pollen extracts and purified natural and recombinant major allergens
1998
Molecular Characterization of an Autoallergen, Hom s 1, Identified by Serum IgE from Atopic Dermatitis Patients11Part of this manuscript was previously published in the proceedings of the 21st Symposium of the Collegium Internationale Allergologicum “Allergy – A Disease of Modern Society”, Int Arch Allergy Immunol 113:209–212, 1998
1998
IgE, Mast Cells, and Eosinophils in Atopic Dermatitis
2011
Molecular characterization of dog albumin as a cross-reactive allergen
1994
Identification of the allergenic components of kiwi fruit and evaluation of their cross-reactivity with timothy and birch pollens
1996
The effect of metronidazole on the cell cycle and DNA in metronidazole-susceptible and -resistant Giardia cell lines
2014
Induction of IgE antibodies with predefined specificity in rhesus monkeys with recombinant birch pollen allergens, Bet v 1 and Bet v 2
1996
Identification of common allergenic structures in mugwort and ragweed pollen
1998
Identification of common allergenic structures in hazel pollen and hazelnuts: A possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen
1992
Exploring the repertoire of IgE-binding self-antigens associated with atopic eczema
2009
Serological and skin‐test diagnosis of birch pollen allergy with recombinant Bet v I, the major birch pollen allergen
1996
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
2000
Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds
2015
Assessment of the allergenic potential of foods derived from genetically engineered crop plants*
1996
Allergenic cross-reactivity among peach, apricot, plum, and cherry in patients with oral allergy syndrome: An in vivo and in vitro study
1994
Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin)
1995
X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy
1996
Lipid-transfer proteins are relevant allergens in fruit allergy
1999
Isochorismate synthase is required to synthesize salicylic acid for plant defence
2001 StandoutNature
Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T‐cell clones specific for Phi p 1, a major grass pollen allergen
1997
Expression of an antibody fragment at high levels in the bacterial cytoplasm
1998 StandoutNobel
Characterization of a lily tapetal transcript that shares sequence similarity with a class of intracellular pathogenesis-related (IPR) proteins
1997
Basic features of crossreactivity in tree and grass Pollen allergy
1997
Amoebiasis
2003 Standout
Combination therapy in the management of giardiasis: What laboratory and clinical studies tell us, so far
2016
Isoforms of Bet v 1, the Major Birch Pollen Allergen, Analyzed by Liquid Chromatography, Mass Spectrometry, and cDNA Cloning
1995
Autoallergy: A pathogenetic factor in atopic dermatitis?
2000
Skin testing with recombinant allergens rBet v 1 and birch profilin, rBet v 2: Diagnostic value for birch pollen and associated allergies
1996
Nuclear pre‐mRNA splicing in yeast
1989
Advantages and Disadvantages of Recombinant Allergens and Peptides for Specific Immunotherapy
1996
Poor biologic activity of cross-reactive IgE directed to carbohydrate determinants of glycoproteins
1997
Pseudomonas aeruginosaantigens as potential vaccines
1997
Proteomics to study genes and genomes
2000 StandoutNature
A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro
2010
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes
2004 StandoutNobel
Cellular Motility Driven by Assembly and Disassembly of Actin Filaments
2003 Standout
Systemic Immunological Changes Induced by Administration of Grass Pollen Allergens via the Oral Mucosa during Sublingual Immunotherapy
1999
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2001 Standout
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Cell biology and molecular basis of denitrification
1997 Standout
[3] Protein engineering of single-chain Fv analogs and fusion proteins
1991
Rapid Diagnostic Assay for Intact Influenza Virus Using a High Affinity Hemagglutinin Binding Protein
2017 StandoutNobel
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Interactions between mRNA Export Commitment, 3′-End Quality Control, and Nuclear Degradation
2002 StandoutNobel
The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding.
1990 StandoutNobel
Structure and Spectroscopy of Copper−Dioxygen Complexes
2004 Standout
Air Pollution and Cardiovascular Disease
2004 Standout
Impaired Parasite Attachment as Fitness Cost of Metronidazole Resistance in Giardia lamblia
2011
The Yeast PRP6 Gene Encodes a U4/U6 Small Nuclear Ribonucleoprotein Particle (snRNP) Protein, and the PRP9 Gene Encodes a Protein Required for U2 snRNP Binding
1990 StandoutNobel
Toxocariasis: Clinical Aspects, Epidemiology, Medical Ecology, and Molecular Aspects
2003 Standout
Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia
2017 StandoutNobel
Biochemistry and Evolution of Anaerobic Energy Metabolism in Eukaryotes
2012
U1 snRNP can influence 3'-splice site selection as well as 5'-splice site selection.
1991 StandoutNobel
Production of a recombinant antibody fragment in whole insect larvae
2007
Innate Immunity to Amebic Liver Abscess Is Dependent on Gamma Interferon and Nitric Oxide in a Murine Model of Disease
2000
Surface plasmon resonance immunosensor for histamine based on an indirect competitive immunoreaction
2006
Review
1997
Macrolide Resistance Conferred by Base Substitutions in 23S rRNA
2001
Pseudomonas aeruginosa antigens as potential vaccines
1997
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Lipopolysaccharide Endotoxins
2002 Standout
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.
1996 StandoutNobel
Modulation of IgE reactivity of allergens by site‐directed mutagenesis: potential use of hypoallergenic variants for immunotherapy
1998
Redox cycling and kinetic analysis of single molecules of solution-phase nitrite reductase
2011 StandoutNobel
Three-Dimensional Structure of the Cross-Reactive Pollen Allergen Che a 3: Visualizing Cross-Reactivity on the Molecular Surfaces of Weed, Grass, and Tree Pollen Allergens
2008
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
cdc12p, a Protein Required for Cytokinesis in Fission Yeast, Is a Component of the Cell Division Ring and Interacts with Profilin
1997 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
A Potential Signaling Role for Profilin in Pollen of Papaver rhoeas
1998
The biochemistry of common aeroallergens
1996
Hom s 4, an IgE-Reactive Autoantigen Belonging to a New Subfamily of Calcium-Binding Proteins, Can Induce Th Cell Type 1-Mediated Autoreactivity
2005
Drug Targets and Mechanisms of Resistance in the Anaerobic Protozoa
2001
How far can we simplify in vitro diagnostics for Fagales tree pollen allergy? A study with three whole pollen extracts and purified natural and recombinant allergens
1999
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Allergen nomenclature*
1995
From Allergen Genes to Allergy Vaccines
2010
Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic.
1992 Standout
Giardia , Entamoeba , and Trichomonas Enzymes Activate Metronidazole (Nitroreductases) and Inactivate Metronidazole (Nitroimidazole Reductases)
2008
Hsp60 Is Targeted to a Cryptic Mitochondrion-Derived Organelle (“Crypton”) in the Microaerophilic Protozoan Parasite Entamoeba histolytica
1999
Works of Michael Duchêne being referenced
Nitroimidazole Action in Entamoeba histolytica: A Central Role for Thioredoxin Reductase
2007
Disrupted intracellular redox balance of the diplomonad fish parasite Spironucleus vortens by 5-nitroimidazoles and garlic-derived compounds
2012
A Low Molecular Weight Allergen of White Birch <i>(Betula verrucosa</i><i>)</i> Is Highly Homologous to Human Profilin
1991
Recombinant dissection of myosin heavy chain of Toxocara canis shows strong clustering of antigenic regions
2001
Immunological and structural similarities among allergens: Prerequisite for a specific and component‐based therapy of allergy
1996
Phosphorothioate Oligonucleotides Reduce Melanoma Growth in a SCID-hu Mouse Model by a Nonantisense Mechanism
1995
Down-regulation of flavin reductase and alcohol dehydrogenase-1 (ADH1) in metronidazole-resistant isolates of Trichomonas vaginalis
2012
Complementary DNA cloning and expression in Escherichia coli of Aln g I, the major allergen in pollen of alder (Alnus glutinosa)
1992
Antibody Production in Baculovirus-Infected Insect Cells
1990
Recombinant allergens for immunoblot diagnosis of tree-pollen allergy
1991
IgE-binding capacity of recombinant timothy grass (Phleum pratense) pollen allergens
1994
The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways
2010
Complementary DNA cloning of the major allergenPhl p I from timothy grass (Phleum pratense); recombinantPhl p I inhibits IgE binding to group I allergens from eight different grass species
1994
cDNA Cloning and Expression of Timothy Grass (Phleum pratense) Pollen Profilin in Escherichia coli: Comparison with Birch Pollen Profilin
1994
Entamoeba histolytica trophozoites transfer lipophosphopeptidoglycans to enteric cell layers
2003
Properties of Tree and Grass Pollen Allergens: Reinvestigation of the Linkage between Solubility and Allergenicity
1993
Induction of specific histamine release from basophils with purified natural and recombinant birch pollen allergens
1993
Molecular consequences of truncations of the first exon forin vitrosplicing of yeast actin pre-mRNA
1988
Humoral immune response against a 70-kilodalton heat shock protein of Entamoeba histolytica in a group of patients with invasive amoebiasis
1992
Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance
2009
Molecular analysis of two hexokinase isoenzymes from Entamoeba histolytica
1995
Nitroimidazole drugs vary in their mode of action in the human parasite Giardia lamblia
2012
Common IgE-epitopes of recombinant Phl p I, the major timothy grass pollen allergen and natural group I grass pollen isoallergens
1996
Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia
2011
Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example
2013
Identification of Profilin as a Novel Pollen Allergen; IgE Autoreactivity in Sensitized Individuals
1991 Science
Protection against experimental Pseudomonas aeruginosa infection by recombinant P. aeruginosa lipoprotein I expressed in Escherichia coli
1990
T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): Evidence for crossreacting and non-crossreacting T-cell epitopes within grass group I allergens
1995
The basic isoform of profilin in pathogenic Entamoeba histolytica
1995
Sequence and transcriptional start site of the Pseudomonas aeruginosa outer membrane porin protein F gene
1988
Identification of profilin as an actin-binding protein in higher plants.
1993
Pyruvate: ferredoxin oxidoreductase from Entamoeba histolytica recognized by a monoclonal antibody.
1996
Profilins constitute a novel family of functional plant pan-allergens.
1992
Pseudomonas aeruginosa outer membrane lipoprotein I gene: molecular cloning, sequence, and expression in Escherichia coli
1989
Localization of alg, opr, phn, pho, 4.5S RNA, 6S RNA, tox, trp, and xcp genes, rrn operons, and the chromosomal origin on the physical genome map of Pseudomonas aeruginosa PAO
1992
Protection against Invasive Amebiasis by a Single Monoclonal Antibody Directed against a Lipophosphoglycan Antigen Localized on the Surface of Entamoeba histolytica
1997
2013