Standout Papers
- Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus (2004)
- Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis (2001)
- Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. (1995)
- Up-Regulation of the Lymphatic Marker Podoplanin, a Mucin-Type Transmembrane Glycoprotein, in Human Squamous Cell Carcinomas and Germ Cell Tumors (2005)
- A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules (2015)
Citation Impact
Citing Papers
Vascular Endothelial Growth Factor-C and C-C Chemokine Receptor 7 in Tumor Cell–Lymphatic Cross-talk Promote Invasive Phenotype
2008
Regulation of Blood and Lymphatic Vascular Separation by Signaling Proteins SLP-76 and Syk
2003 Science
Functionally specialized junctions between endothelial cells of lymphatic vessels
2007 Standout
Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis
2008
Reconstituting Organ-Level Lung Functions on a Chip
2010 StandoutScience
Vascular Endothelial Growth Factor-A Promotes Peritumoral Lymphangiogenesis and Lymphatic Metastasis
2005
Tumor-Secreted Vascular Endothelial Growth Factor-C Is Necessary for Prostate Cancer Lymphangiogenesis, but Lymphangiogenesis Is Unnecessary for Lymph Node Metastasis
2005
Phenotypic Overlap Between Hematopoietic Cells with Suggested Angioblastic Potential and Vascular Endothelial Cells
2002
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation
2004 Standout
Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature
2007
Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis
1998
Developmental and pathological lymphangiogenesis: from models to human disease
2008
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Hypoxia Increases Breast Cancer Cell-Induced Lymphatic Endothelial Cell Migration
2008
Chemokine Networks and Breast Cancer Metastasis
2007
Heterogeneity of the Tumor Vasculature
2010
Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation
2006
Cutaneous Wound Healing
1999 Standout
Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1)
2004
Vascular Endothelial Growth Factor-C Accelerates Diabetic Wound Healing
2006
Inflammation and cancer
2002 StandoutNature
Lymphangiogenesis and cancer metastasis
2002 Standout
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Endogenous inhibitors of angiogenesis
2009
HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
2005 StandoutNobel
Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
2004
Tumor-Induced Sentinel Lymph Node Lymphangiogenesis and Increased Lymph Flow Precede Melanoma Metastasis
2007
Psoriasis
2009 Standout
Focus on lymphangiogenesis in tumor metastasis
2005
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
1990 Standout
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
2005 Standout
Animal models of psoriasis: a critical appraisal
2008
Impaired angiogenesis in the aging kidney: Vascular endothelial growth factor and Thrombospondin-1 in renal disease
2001
TGF-β–dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis
2008
Upregulation of intercellular adhesion molecule-1 (ICAM-1) expression in primary cultures of human brain microvessel endothelial cells by cytokines and lipopolysaccharide
1992
Clinical translation of angiogenesis inhibitors
2002 Standout
B Cell-Driven Lymphangiogenesis in Inflamed Lymph Nodes Enhances Dendritic Cell Mobilization
2006
How Tumors Become Angiogenic
1996
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
2006
Pathogenesis and clinical features of psoriasis
2007 Standout
Piezo1 incorporates mechanical force signals into the genetic program that governs lymphatic valve development and maintenance
2019
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
2002
Tumor metastasis and the lymphatic vasculature
2009
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Single-Nucleotide Polymorphisms of Vascular Endothelial Growth Factor in Psoriasis of Early Onset
2004
Deciphering and Reversing Tumor Immune Suppression
2013
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
2001
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
2003
T1 /podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema
2003 Standout
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
A reevaluation of integrins as regulators of angiogenesis
2002
Genesis and pathogenesis of lymphatic vessels
2003
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
2002 Standout
Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis
2009
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Altered Expression of Angiopoietins and Tie2 Endothelium Receptor in Psoriasis
2001
During angiogenesis, vascular endothelial growth factor regulate natural killer cell adhesion to tumor endothelium
1996
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Systems Biology of Vascular Endothelial Growth Factors
2008
A Human Interleukin-12/23 Monoclonal Antibody for the Treatment of Psoriasis
2007
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice
2008
Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation
2007
Telomere states and cell fates
2000 StandoutNatureNobel
Cancer and viral infections in immunocompromised individuals
2009
High Expression of Vascular Endothelial Growth Factor Predicts Early Recurrence and Poor Prognosis after Curative Resection for Ductal Adenocarcinoma of the Pancreas
2002
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
2005 StandoutNobel
Pericytes: gatekeepers in tumour cell metastasis?
2007
The Hallmarks of Cancer
2000 Standout
The biology of VEGF and its receptors
2003 Standout
Mutations in the Transcription Factor Gene SOX18 Underlie Recessive and Dominant Forms of Hypotrichosis-Lymphedema-Telangiectasia
2003
Lymphatic and angiogenic characteristics in breast cancer: morphometric analysis and prognostic implications
2008
Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Tumor-Induced Lymph Flow
2008
Specialization of tumour vasculature
2002
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature
2005
Angiogenesis in health and disease
2003 Standout
Lymphatic vasculature development
2004
Lymphangiogenic Growth Factor Responsiveness Is Modulated by Postnatal Lymphatic Vessel Maturation
2006
Expression of platelet‐derived growth factor (PDGF)‐B and PDGF‐receptor β is associated with lymphatic metastasis in human gastric carcinoma
2010
Lymphangiogenesis in development and human disease
2005 StandoutNature
Oncogenes as inducers of tumor angiogenesis
1995
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
2005 Nature
Psoriasis pathophysiology: current concepts of pathogenesis
2005
Transcriptional Regulation of Vascular Endothelial Growth Factor C by Oxidative and Thermal Stress Is Mediated by Lens Epithelium-Derived Growth Factor/p75
2009
Thrombospondins: from structure to therapeutics
2008
VEGF receptor signalling ? in control of vascular function
2006 Standout
Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblasts
2001
Dual origin of avian lymphatics
2006
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Aging and Survival of Cutaneous Microvasculature
2002
Psoriasis: emerging therapeutic strategies
2005
Sustained expression of Hif‐1α in the diabetic environment promotes angiogenesis and cutaneous wound repair
2007
Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants
2006
Getting under the skin: the immunogenetics of psoriasis
2005
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?
2002
Angiogenesis in life, disease and medicine
2005 StandoutNature
Cancer as an overhealing wound: an old hypothesis revisited
2008 Standout
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
2003 Standout
Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos
2008
Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis
2007
Tumor Induction of VEGF Promoter Activity in Stromal Cells
1998
High interstitial fluid pressure — an obstacle in cancer therapy
2004 Standout
Clinical Applications of Research on Angiogenesis
1995 Standout
Autologous Chemotaxis as a Mechanism of Tumor Cell Homing to Lymphatics via Interstitial Flow and Autocrine CCR7 Signaling
2007
Emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis
2005
Molecular regulation of angiogenesis and lymphangiogenesis
2007 Standout
VEGF and the quest for tumour angiogenesis factors
2002
Emerging Biological Principles of Metastasis
2017 Standout
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages
2005
Innate and adaptive immunity and the pathophysiology of psoriasis
2006
Switching and Signaling at the Telomere
2001 StandoutNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging
1998
The metastatic niche: adapting the foreign soil
2009
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
2004
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
1999
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
The Link between Lymphatic Function and Adipose Biology
2008
The biology of vascular endothelial growth factors
2005
Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?
2003
The STATs of cancer — new molecular targets come of age
2004 Standout
Inflammatory Manifestations of Experimental Lymphatic Insufficiency
2006
Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy
2006
Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans
2009
Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model
2008
α5β1 Integrin Blockade Inhibits Lymphangiogenesis in Airway Inflammation
2009
Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and ‘Type 1’ inflammatory gene expression
2004
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
1996 StandoutNature
Psoriasis
2005
Lymphangiogenesis and lymphatic metastasis in breast cancer
2009
Vascular endothelial growth factor (VEGF) expression and survival in human epithelial ovarian carcinomas
1997
Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation
2004
Animal models of psoriasis
2007
Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema
2008
From Classical Mouse Models of Psoriasis to a Spontaneous Xenograft Model Featuring Use of AGR Mice
2006
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
1996 StandoutNature
Cross-species Vascular Endothelial Growth Factor (VEGF)-blocking Antibodies Completely Inhibit the Growth of Human Tumor Xenografts and Measure the Contribution of Stromal VEGF
2005
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
2009
Tumor-Associated Macrophages Express Lymphatic Endothelial Growth Factors and Are Related to Peritumoral Lymphangiogenesis
2002 Standout
Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability
1999
Proliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristics
2008
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
2004
The role of pericytes in blood-vessel formation and maintenance
2005
A phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer
2003
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Human Endothelial Cell Life Extension by Telomerase Expression
1999
Adrenomedullin signaling is necessary for murine lymphatic vascular development
2007
Involvement of the Snake Toxin Receptor CLEC-2, in Podoplanin-mediated Platelet Activation, by Cancer Cells
2007
VEGFs, receptors and angiogenesis
1999
Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor
1998 Standout
Mouse Models of Psoriasis
2007
Critical roles of VEGF‐C‐VEGF receptor 3 in reconnection of the collecting lymph vessels in mice
2008
Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation
2005
Endogenous Inhibitors of Angiogenesis
2005
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Molecular Biology and Pathology of Lymphangiogenesis
2008 Standout
Angiogenesis
2005
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α
2000 StandoutNobel
In Vivo Actions of Angiopoietins on Quiescent and Remodeling Blood and Lymphatic Vessels in Mouse Airways and Skin
2006
Heterogeneity of Endothelial Cells
1997
Endothelial-Mural Cell Signaling in Vascular Development and Angiogenesis
2009
Abnormal lymphatic vessel development in neuropilin 2 mutant mice
2002
Preexisting Lymphatic Endothelium but not Endothelial Progenitor Cells Are Essential for Tumor Lymphangiogenesis and Lymphatic Metastasis
2004
Vascular Endothelial Cell Growth Factor Receptor 3–Mediated Activation of Lymphatic Endothelium Is Crucial for Tumor Cell Entry and Spread via Lymphatic Vessels
2005
Inhibition of endogenous TGF-β signaling enhances lymphangiogenesis
2008
Constitutive and inducible expression and regulation of vascular endothelial growth factor
2004
Emilin1 Deficiency Causes Structural and Functional Defects of Lymphatic Vasculature
2008
Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages
2008
Lymphatic Metastasis in the Absence of Functional Intratumor Lymphatics
2002 StandoutScience
Role of angiogenesis in tumor growth and metastasis
2002 Standout
Inhibition of Lymphogenous Metastasis Using Adeno-Associated Virus-Mediated Gene Transfer of a Soluble VEGFR-3 Decoy Receptor
2005
Therapeutic Targeting of the Tumor Microenvironment
2021
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
2002
Imaging‐Guided Combined Photothermal and Radiotherapy to Treat Subcutaneous and Metastatic Tumors Using Iodine‐131‐Doped Copper Sulfide Nanoparticles
2015
Vascular Endothelial Growth Factor D Is Dispensable for Development of the Lymphatic System
2005
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
1996
Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3
2010
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-κB and Prox1
2009
Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro
2007
Lymphotoxin β receptor signaling is required for inflammatory lymphangiogenesis in the thyroid
2007
Leaky vessels? Call Ang1!
2000
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
2005
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
2004
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation
2010
Spontaneous Development of Psoriasis in a New Animal Model Shows an Essential Role for Resident T Cells and Tumor Necrosis Factor-α
2004
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Imaging Steps of Lymphatic Metastasis Reveals That Vascular Endothelial Growth Factor-C Increases Metastasis by Increasing Delivery of Cancer Cells to Lymph Nodes: Therapeutic Implications
2006
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Liposomal Indocyanine Green for Enhanced Photothermal Therapy
2017
Angiogenesis
2006
Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution
2009
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Angiogenesis: a Dynamic Balance of Stimulators and Inhibitors
1997
Lymph sacs are not required for the initiation of lymph node formation
2008
Normal Lymphatic Development and Function in Mice Deficient for the Lymphatic Hyaluronan Receptor LYVE-1
2006
Osteopontin
2000 Standout
Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: Role of vascular endothelial growth factor
1998
VEGF differentially activates STAT3 in microvascular endothelial cells
2003
Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice
2009
Angiogenesis in Endocrine Tumors
2003
Age-Dependent Impairment of Reendothelialization After Arterial Injury
2003
Inhibition of VEGFR-3 Activation with the Antagonistic Antibody More Potently Suppresses Lymph Node and Distant Metastases than Inactivation of VEGFR-2
2006
Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
2007
Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
1998 Standout
Mutations in FOXC2 Are Strongly Associated With Primary Valve Failure in Veins of the Lower Limb
2007
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing.
1998 Standout
Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways
2008
Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis
1998
Osteopontin at the Crossroads of Inflammation and Tumor Progression
2017
Age-Related Changes in Vascular Endothelial Growth Factor Dependency and Angiopoietin-1-Induced Plasticity of Adult Blood Vessels
2004
Inflamed Lymphatic Endothelium Suppresses Dendritic Cell Maturation and Function via Mac-1/ICAM-1-Dependent Mechanism
2009
The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications
2004
Works of Michael Detmar being referenced
Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green
2010
Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy.
2002
The Lymphatic System in Health and Disease
2008
Nuclear Translocation of Phosphorylated STAT3 Is Essential for Vascular Endothelial Growth Factor-induced Human Dermal Microvascular Endothelial Cell Migration and Tube Formation
2003
Identification of Vascular Lineage-Specific Genes by Transcriptional Profiling of Isolated Blood Vascular and Lymphatic Endothelial Cells
2003
Overexpression of Thrombospondin-1 Decreases Angiogenesis and Inhibits the Growth of Human Cutaneous Squamous Cell Carcinomas
1999
Concurrent Induction of Lymphangiogenesis, Angiogenesis, and Macrophage Recruitment by Vascular Endothelial Growth Factor-C in Melanoma
2001
Hepatocyte growth factor promotes lymphatic vessel formation and function
2005
Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes
2005
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
2001 Standout
Lymphatic endothelium in health and disease
2008
Inhibition of Chronic and Acute Skin Inflammation by Treatment with a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor
2008
Murine psoriasis-like disorder induced by naive CD4+ T cells
1997
New Insights into the Molecular Control of the Lymphatic Vascular System and its Role in Disease
2006
Vascular Endothelial Growth Factor-A Mediates Ultraviolet B-Induced Impairment of Lymphatic Vessel Function
2006
New insights into the biology and pathology of the cutaneous lymphatic system
2003
Activation of the Tie2 Receptor by Angiopoietin-1 Enhances Tumor Vessel Maturation and Impairs Squamous Cell Carcinoma Growth
2002
Growth Hormone Promotes Lymphangiogenesis
2008
Up-Regulation of the Lymphatic Marker Podoplanin, a Mucin-Type Transmembrane Glycoprotein, in Human Squamous Cell Carcinomas and Germ Cell Tumors
2005 Standout
Vascular Endothelial Growth Factor-C (VEGF-C) and its Receptors KDR and flt-4 are Expressed in AIDS-Associated Kaposi’s Sarcoma
1999
Effects of rIFN Alpha, Beta, and Gamma on the Morphology, Proliferation, and Cell Surface Antigen Expression of Human Dermal Microvascular Endothelial Cells In Vitro
1990
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis
2008
Vascular Permeability Factor/Vascular Endothelial Growth Factor: An Important Mediator of Angiogenesis in Malignancy and Inflammation
1995
Tumor Lymphangiogenesis
2003
Interaction of tumor cells and lymphatic vessels in cancer progression
2011
Angiogenesis and lymphangiogenesis of skin cancers
2004
Tumor progression: the effects of thrombospondin-1 and -2
2004
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus
2004 Standout
Expression of Vascular Endothelial Growth Factor Induces an Invasive Phenotype in Human Squamous Cell Carcinomas
2000
An N-Terminal 80 kDa Recombinant Fragment of Human Thrombospondin-2 Inhibits Vascular Endothelial Growth Factor Induced Endothelial Cell Migration In Vitro and Tumor Growth and Angiogenesis In Vivo
2003
Vascular permeability factor/vascular endothelial growth factor:A multifunctional angiogenic cytokine
1997
The Angiogenesis Inhibitor Vasostatin does not Impair Wound Healing at Tumor-Inhibiting Doses
2001
Interaction between Genetic Control of Vascular Endothelial Growth Factor Production and Retinoid Responsiveness in Psoriasis
2005
Endothelialized Networks with a Vascular Geometry in Microfabricated Poly(dimethyl siloxane)
2004
Control of hair growth and follicle size by VEGF-mediated angiogenesis
2001
Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice
2002
In Vivo Detection of Human Vascular Endothelial Growth Factor Promoter Activity in Transgenic Mouse Skin
2000
Angiogenesis, lymphangiogenesis, and melanoma metastasis
2003
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells
1997
Prox1, master regulator of the lymphatic vasculature phenotype
2003
The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature
2002
Multifocal Lymphangioendotheliomatosis With Thrombocytopenia
2004
Hypoxia Regulates the Expression of Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF) and its Receptors in Human Skin
1997
Stable Expression of Angiopoietin-1 and Other Markers by Cultured Pericytes: Phenotypic Similarities to a Subpopulation of Cells in Maturing Vessels During Later Stages of Angiogenesis In Vivo
2002
Expression of the Type-1 Repeats of Thrombospondin-1 Inhibits Tumor Growth Through Activation of Transforming Growth Factor-β
2004
Effect of Recombinant Tumor Necrosis Factor-Alpha on Cultured Microvascular Endothelial Cells Derived From Human Dermis
1990
Evidence for Vascular Endothelial Growth Factor (VEGF) as a Modifier Gene in Psoriasis
2004
Development of the lymphatic vascular system: A mystery unravels
2004
Growth of human hair follicle keratinocytes in vitro
1987
Tumor lymphangiogenesis and melanoma metastasis
2008
The α1β1 and α2β1 Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis
2002
Multiple roles of lymphatic vessels in tumor progression
2018
Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate
2002
Pathways Targeting Tumor Lymphangiogenesis
2006
Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis.
1994
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
2005
Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.
1996
Mechanisms of lymphatic metastasis
2014
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.
1995 Standout
Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis
2008
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
2015 Standout
VEGF-C–induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
2006
Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis
1999
Tumor and lymph node lymphangiogenesis—impact on cancer metastasis
2006
Lymphangiogenesis in development and disease
2007
Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia
2004
Angiogenesis promoted by vascular endothelial growth factor: Regulation through α1β1and α2β1 integrins
1997
Induction of lymphatic endothelial cell differentiation in embryoid bodies
2005
A critical role of placental growth factor in the induction of inflammation and edema formation
2002
VEGF‐A promotes tissue repair‐associated lymphatic vessel formation via VEGFR‐2 and the α1β1 and α2β1 integrins
2004
Uterine smooth muscle cells express functional receptors (flt-1 and KDR) for vascular permeability factor/vascular endothelial growth factor.
1997
Prox1 Promotes Lineage-specific Expression of Fibroblast Growth Factor (FGF) Receptor-3 in Lymphatic Endothelium: A Role for FGF Signaling in Lymphangiogenesis
2005
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes
2007
Vascular Permeability Factor/Vascular Endothelial Growth Factor Induces Lymphangiogenesis as well as Angiogenesis
2002
Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis
2003
Identification of a Human VPF/VEGF 3′ Untranslated Region Mediating Hypoxia-induced mRNA Stability
1998
Lymphatic vessels in cancer
2022