Citation Impact
Citing Papers
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
2003 StandoutNobel
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 StandoutScience
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
2010 StandoutNobel
Radiation-induced deletions in the 5' end region of Notch1 lead to the formation of truncated proteins and are involved in the development of mouse thymic lymphomas
2003
Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice
2002
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
2009
Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis
2002
Ikaros Directly Represses the Notch Target Gene Hes1 in a Leukemia T Cell Line
2008
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development
2008
Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells
2005
Direct regulation of the Nrarp gene promoter by the Notch signaling pathway
2004
Innate IL-17-producing cells: the sentinels of the immune system
2010 Standout
Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1
1999
The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate
2000 Nature
Angiogenesis: A Team Effort Coordinated by Notch
2009
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
2009 StandoutNature
Cortisol regulates the expression of Notch in osteoblasts
2002
Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4+ T cells
2000
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex
2002
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells
2003
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice
2000
A New Twist in TCR Diversity Revealed by a Forbidden αβ TCR
2007 StandoutNobel
T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
2008
T cell acute lymphoblastic leukemia/lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling
2004
Notch signaling regulates left–right asymmetry determination by inducingNodalexpression
2003
Osteoblastic cells regulate the haematopoietic stem cell niche
2003 StandoutNature
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
2000
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Deficient Positive Selection of CD4 T Cells in Mice Displaying Altered Repertoires of MHC Class II–Bound Self-Peptides
1997
Notch1 Regulates Maturation of CD4+ and CD8+ Thymocytes by Modulating TCR Signal Strength
2001
Inactivation of Notch1 Impairs VDJβ Rearrangement and Allows pre-TCR-Independent Survival of Early αβ Lineage Thymocytes
2002
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
2003 Standout
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin Ligase
2000
Inducible gene knockout of transcription factor recombination signal binding protein‐J reveals its essential role in T versus B lineage decision
2002 StandoutNobel
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Notch regulation of lymphocyte development and function
2004
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Nrarp Coordinates Endothelial Notch and Wnt Signaling to Control Vessel Density in Angiogenesis
2009
Notch promotes survival of pre–T cells at the β-selection checkpoint by regulating cellular metabolism
2005
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
2002
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development
2001
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro
2002
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
2004
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination
1999 Standout
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling
2005
Molecular determinants of TCR expression and selection
2001
β-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
2003
Cancer-related inflammation
2008 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Plasmacytoid Dendritic Cells Activate Lymphoid-Specific Genetic Programs Irrespective of Their Cellular Origin
2004
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
The HIN-200 family: More than interferon-inducible genes?
2005
Notch and T cell malignancy
2004
Characterization and Quantitation of Peptide–MHC Complexes Produced from Hen Egg Lysozyme Using a Monoclonal Antibody
1997
Rheumatoid Arthritis
1996
Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice
2002
Heterogeneity among DN1 Prothymocytes Reveals Multiple Progenitors with Different Capacities to Generate T Cell and Non-T Cell Lineages
2004
Notch signaling controls the generation and differentiation of early T lineage progenitors
2005
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals
2004
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Oh no, Notch again!
2000
TCR-Mediated Notch Signaling Regulates Proliferation and IFN-γ Production in Peripheral T Cells
2003
Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus
2001
A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
2001 StandoutNobel
Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling
2003
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
2001
Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression
2003
Glucocorticoids in T Cell Development and Function
2000
IL-17 and Th17 Cells
2009 Standout
The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
2008
Notch Activation Is an Early and Critical Event during T-Cell Leukemogenesis in Ikaros-Deficient Mice
2005
Notch signalling via RBP-J promotes myeloid differentiation
2000
Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein
1997
Major Histocompatibility Complex Class II Compartments in Human and Mouse B Lymphoblasts Represent Conventional Endocytic Compartments
1997
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
Snail family genes are required for left–right asymmetry determination, but not neural crest formation, in mice
2006
Clonally-related Immunoglobulin VH Domains and Nonrandom Use of DH Gene Segments in Rheumatoid Arthritis Synovium
1998
Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors
2000
Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor–Ligand Interactions
2004
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
2000 StandoutScienceNobel
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells
2000
Requirement for RORγ in Thymocyte Survival and Lymphoid Organ Development
2000 Science
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Cancer Genome Landscapes
2013 StandoutScience
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
A Reassessment of the Effect of Activated Notch1 on CD4 and CD8 T Cell Development
2002
Identification of CD25+ γδ T Cells As Fetal Thymus-Derived Naturally Occurring IL-17 Producers
2008
Notch2 Haploinsufficiency Results in Diminished B1 B Cells and a Severe Reduction in Marginal Zone B Cells
2003
Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factors.
1993
Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells
2001
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
The Role of B7 Costimulation in CD4/CD8 T Cell Homeostasis
2000 StandoutNobel
Notch-Regulated Ankyrin-Repeat Protein Inhibits Notch1 Signaling: Multiple Notch1 Signaling Pathways Involved In T Cell Development
2003
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Analysis of Notch1 Function by In Vitro T Cell Differentiation of Pax5 Mutant Lymphoid Progenitors
2004
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
MOLECULAR GENETICS OF T CELL DEVELOPMENT
2004
Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation
2001
Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes
2003
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Works of Michael Deftos being referenced
Notch1 Signaling Promotes the Maturation of CD4 and CD8 SP Thymocytes
2000
A study of complexes of class II invariant chain peptide: Major histocompatibility complex class II molecules using a new complex‐specific monoclonal antibody
1996
Notch signaling in T cell development
2000
The Nrarp Gene Encodes an Ankyrin-Repeat Protein That Is Transcriptionally Regulated by the Notch Signaling Pathway
2001
Generation and Characterization of two Monoclonal Self‐Associating IgG Rheumatoid Factors from a Rheumatoid Synovium
1992
Correlating Notch Signaling with Thymocyte Maturation
1998
RORγt, a Novel Isoform of an Orphan Receptor, Negatively Regulates Fas Ligand Expression and IL-2 Production in T Cells
1998
Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response.
1992
Down-Regulation of the Orphan Nuclear Receptor RORγt Is Essential for T Lymphocyte Maturation
2000