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Citing Papers
Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer
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Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
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Probing mucin-type O-linked glycosylation in living animals
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Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
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Metagenomic Analysis of the Human Distal Gut Microbiome
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Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research.
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Consumption of the Putative Chemopreventive Agent Curcumin by Cancer Patients: Assessment of Curcumin Levels in the Colorectum and their Pharmacodynamic Consequences
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The DNA-damage response in human biology and disease
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Uptake and retention of nitroimidazole-carboranes designed for boron neutron capture therapy in experimental murine tumours: 11 detection by B magnetic resonance spectroscopy
1996
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Curcumin–glutathione interactions and the role of human glutathione S-transferase P1-1
2000
Boron Neutron Capture Therapy of Brain Tumors: Past History, Current Status, and Future Potential
1996
Targeting hypoxia in cancer therapy
2011 Standout
Multifunctional Lipid/Quantum Dot Hybrid Nanocontainers for Controlled Targeting of Live Cells
2006 StandoutNobel
Chemical Radiosensitizers for Use in Radiotherapy
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Contemporary progresses on neutral, highly emissive Os(ii) and Ru(ii) complexes
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Curcumin impairs tumor suppressor p53 function in colon cancer cells
2004
Carbon–heteroatom bond formation catalysed by organometallic complexes
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Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage
2007
Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis
1995
Copper(II)‐Catalyzed Three‐Component Cascade Annulation of Diaryliodoniums, Nitriles, and Alkynes: A Regioselective Synthesis of Multiply Substituted Quinolines
2013
Peroxisomal Dysfunction in Age-Related Diseases
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Redox cycling and sulphydryl arylation; Their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes
1988
Curcumin as “Curecumin”: From kitchen to clinic
2007 Standout
Beneficial Effects Of GPI 6150, an Inhibitor of Poly(ADP-Ribose) Polymerase in a Rat Model of Splanchnic Artery Occlusion and Reperfusion
2002
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
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PD98059 Is an Equipotent Antagonist of the Aryl Hydrocarbon Receptor and Inhibitor of Mitogen-Activated Protein Kinase Kinase
1998
Biological Functions of Autophagy Genes: A Disease Perspective
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Unusual Cytochrome P450 Enzymes and Reactions
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Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Approaching a stable, green twisted heteroacene through “clean reaction” strategy
2012
3 The Medicinal Chemistry of the Azido Group
1994
Stimulated Release of Size‐Selected Cargos in Succession from Mesoporous Silica Nanoparticles
2012 StandoutNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Combining bioreductive drugs and radiation for the treatment of solid tumors
2003
Effects of Parp Inhibition on Drug and FAS-Induced Apoptosis in Leukaemic Cells
1999
Understanding the Odd Science of Aging
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GPI 6150 Prevents H2O2 Cytotoxicity by Inhibiting Poly(ADP-ribose) Polymerase
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Non-steroidal anti-inflammatory drugs (NSAIDs) for colorectal cancer prevention
2003
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
Crystal structure of the Src family tyrosine kinase Hck
1997 Nature
Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential
2007
Synthesis and radioiodination of a nido-1,2-carboranyl derivative of 2-nitroimidazole
1994
SR 4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours
1993
Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine
2003
Suppression of cell cycle progression by flavonoids: dependence on the aryl hydrocarbon receptor
1999
Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration
2004
Targeting tumors with hypoxia-activated cytotoxins
2007
Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos
2009
CURCUMIN: THE INDIAN SOLID GOLD
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Role of Poly(ADP‐ribose) polymerase 1 (PARP‐1) in Cardiovascular Diseases: The Therapeutic Potential of PARP Inhibitors
2007
Thioredoxin Reductase Is Irreversibly Modified by Curcumin
2005
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
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Enhanced polyadenosine diphosphate‐ribosylation in cirrhotic liver and carcinoma tissues in patients with hepatocellular carcinoma
2001
Curcumin–phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats
2006
ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by β-Adrenergic Receptors
1999 StandoutNobel
Introduction to Metal–Organic Frameworks
2012 StandoutNobel
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
New inhibitors of poly(ADP-ribose) polymerase and their potential therapeutic targets
2002
Bioavailability of Curcumin: Problems and Promises
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Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
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Three-component coupling reaction of benzylic halides, carbon dioxide, and N,N-dimethylformamide by using paired electrolysis: sacrificial anode-free efficient electrochemical carboxylation of benzylic halides
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Activation of poly(ADP-ribose) polymerase in severe hemorrhagic shock and resuscitation
2001
Synthesis and biological properties of bioreductively targeted nitrothienyl prodrugs of combretastatin A-4
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Polymeric Systems for Controlled Drug Release
1999 Standout
Luminescent Chemodosimeters for Bioimaging
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Miscanthus: a fast‐growing crop for biofuels and chemicals production
2012
Organocatalysis by N-Heterocyclic Carbenes
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Anticancer potential of curcumin: preclinical and clinical studies.
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Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
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Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides
2009
Hydrogels for Tissue Engineering
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Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
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Preparation of C-2-pyridyl derivatives of icosahedral carboranes via copper(I) intermediates
1996
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
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Phase I Clinical Trial of Oral Curcumin
2004
Lignin Valorization: Improving Lignin Processing in the Biorefinery
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Microwave-Assisted and Continuous Flow Multistep Synthesis of 4-(Pyrazol-1-yl)carboxanilides
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Current methods for the synthesis of 2-substituted azoles
2004
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
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Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Azine Activation via Silylium Catalysis
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Electron Injection from Copper Diimine Sensitizers into TiO2: Structural Effects and Their Implications for Solar Energy Conversion Devices
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Copper in cross-coupling reactions
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Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
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Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
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C–H Functionalization of Azines
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The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Generation of Superparamagnetic Liposomes Revealed as Highly Efficient MRI Contrast Agents for in Vivo Imaging
2005
Hypoxia-Selective Antitumor Agents. 16. Nitroarylmethyl Quaternary Salts as Bioreductive Prodrugs of the Alkylating Agent Mechlorethamine
2001
Controlled Ring-Opening Polymerization of Lactide and Glycolide
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The Chemistry of Neutron Capture Therapy
1998 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
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De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
The chemistry of boron analogues of biomolecules
1994
Physiology and pathophysiology of poly(ADP‐ribosyl)ation *
2001
Synthesis of 1,7-bis(carboxyalkylcarbamoyl)-m-carboranes as precursors of possible water-soluble preparations for boron-neutron-capture treatment of cancer
1996
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Regulation of the nuclear proteasome activity in myelomonocytic human leukemia cells after adriamycin treatment
2001
Atropo-Enantioselective Total Synthesis of Knipholone and Related Antiplasmodial Phenylanthraquinones
2002
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
2010 Standout
Silver-Catalyzed Csp−H and Csp−Si Bond Transformations and Related Processes
2008
Proton-Coupled Electron Transfer
2012 Standout
Structural and Photophysical Studies of Phosphorescent Three-Coordinate Copper(I) Complexes Supported by an N-Heterocyclic Carbene Ligand
2012
Carbaboranes as Pharmacophores: Properties, Synthesis, and Application Strategies
2011
Works of Michael D. Threadgill being referenced
Synthesis of thiophenecarboxamides, thieno[3,4-c]pyridin-4(5H)-ones and thieno[3,4-d]pyrimidin-4(3H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP)
1999
Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases
2015
5-Aminoisoquinolinone, a potent inhibitor of poly (adenosine 5′-diphosphate ribose) polymerase, reduces myocardial infarct size
2001
2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the parp inhibitor 5-bromoisoquinolinone
1999
Effects of 5‐aminoisoquinolinone, a water‐soluble, potent inhibitor of the activity of poly (ADP‐ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock
2000
Substituted flavones as aryl hydrocarbon (Ah) receptor agonists and antagonists
1996
α-Methylacyl-CoA racemase (AMACR): Metabolic enzyme, drug metabolizer and cancer marker P504S
2013
Synthesis of a series of nitrothiophenes with basic or electrophilic substituents and evaluation as radiosensitizers and as bioreductively activated cytotoxins
1991
Poly(ADP-ribosylation) as target for cancer chemotherapy
1993
Poly(ADP-ribose)polymerase Inhibition - Where Now?
2005
Synthesis and evaluation of .alpha.-[[(2-haloethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanols as prodrugs of .alpha.-[(1-aziridinyl)methyl]-2-nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogs which are radiosensitizers and bioreductively activated cytotoxins
1990
Applications of tandem mass spectrometry to the characterization of derivatized glutathione conjugates. Studies withS-(N-Methylcarbamoyl)-glutathione, a metabolite of the antineoplastic agentN-methylformamide
1988
Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and Secondary Damage in Experimental Spinal Cord Trauma
2005
Isolation, identification and quantitation of hydroxycinnamic acid conjugates, potential platform chemicals, in the leaves and stems of Miscanthus×giganteus using LC–ESI-MS
2011
Identification of 3′-Methoxy-4′-nitroflavone as a Pure Aryl Hydrocarbon (Ah) Receptor Antagonist and Evidence for More Than One Form of the Nuclear Ah Receptor in MCF-7 Human Breast Cancer Cells
1995
Synthesis of 3-Substituted Benzamides and 5-Substituted Isoquinolin-1(2H)-ones and Preliminary Evaluation as Inhibitors of Poly(ADP-ribose)polymerase (PARP)
1998
S-2-Amino-5-azolylpentanoic Acids Related to l-Ornithine as inhibitors of the isoforms of nitric oxide synthase (NOS)
1998
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury
2002
2-Nitroimidazole dual-function bioreductive drugs: studies on the effects of regioisomerism and side-chain structural modifications on differential cytotoxicity and radiosensitization by aziridinyl and oxiranyl derivatives
1992
The metabolism of a stable N-hydroxymethyl derivative of a N-methylamide
1983
5-Nitroisocoumarins from tandem Castro–Stephens coupling—6-endo-dig cyclisation of 2-iodo-3-nitrobenzoic acid and arylethynes and ring-closure of methyl 2-alkynyl-3-nitrobenzoates with electrophiles
2006
Formation and dehydration of a series of 5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazoles
1999
1H NMR studies on the reductively triggered release of heterocyclic and steroid drugs from 4,7-dioxoindole-3-methyl prodrugs
2003
Closo→nido cage degradation of 1-(substituted-phenyl)-1,2-dicarbadodecaborane(12)s in wet DMSO under neutral conditions
2007
Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases.
1992
Structural studies on bio-active compounds. Part 6. Determination of the sites of protonation on three 2,4-diaminopyrimidines of pharmaceutical importance by proton-coupled 13C and 1H nuclear magnetic resonance spectroscopy
1987
Tumour-targetted boranes. Part 2. Coupling of closo-carboranes to substituted 2-nitroimidazoles via 1,3-dipolar cycloaddition
1994
The role of oxidative processes in the cytotoxicity of substituted 1,4-naphthoquinones in isolated hepatocytes
1986
Structural studies on bio-active compounds. Part 12. Tautomerism and conformation of aryl-substituted 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones in the solid phase and in solution
1989
The metabolism of triazene antitumor drugs
1987
Tumour-targetted boranes. Part 3. Synthesis of carbamate-linked nitroimidazolyl carboranes designed for boron neutron capture therapy of cancer
1994
Design, Synthesis, and Evaluation in Vitro of Quinoline-8-carboxamides, a New Class of Poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) Inhibitor
2008
Synthesis of carborane-containing nitroimidazole compounds via mild 1,3-dipolar cycloadition
1992
Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis.
2002
Macromolecular systems for chemotherapy and magnetic resonance imaging
1996
5-Nitrofuran-2-ylmethyl group as a potential bioreductively activated pro-drug system
1997
Structural studies on bioactive compounds. 4. A structure-antitumor activity study on analogs of N-methylformamide
1986
Tumor-Targeted Boranes. 4. Synthesis of Nitroimidazole-Carboranes with Polyether-Isoxazole Links
1994
Labelled compounds of interest as antitumour agents. Part 41. Deuteration and tritiation of a nitroimidazole‐carborane designed for BNCT
1994
N- and O-Alkylation of isoquinolin-1-ones in the Mitsunobu reaction: development of potential drug delivery systems
2002