Standout Papers
Citation Impact
Citing Papers
Human Hypertension Caused by Mutations in WNK Kinases
2001 StandoutScience
K + Channel Mutations in Adrenal Aldosterone-Producing Adenomas and Hereditary Hypertension
2011 Science
Case Detection, Diagnosis, and Treatment of Patients with Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline
2008 Standout
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Finishing the euchromatic sequence of the human genome
2004 StandoutNature
Primary aldosteronism: from genesis to genetics
2003
Caught up in a Wnt storm: Wnt signaling in cancer
2003
The regulation of aldosterone synthase expression
2003
Molecular genetics of human hypertension
1998
Primary aldosteronism—careful investigation is essential and rewarding
2003
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Glucocorticoid-Remediable Aldosteronism
2003
A novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22)
2000
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
2010 StandoutNature
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
Laboratory challenges in primary aldosteronism screening and diagnosis
2015
Molecular Mechanisms of Human Hypertension
2001 Standout
Glucocorticoid-remediable Aldosteronism
2011
Molecular basis of human hypertension: Role of angiotensinogen
1992 Standout
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
1999
Evidence for Abnormal Left Ventricular Structure and Function in Normotensive Individuals with Familial Hyperaldosteronism Type I
2005
Glucocorticoid-remediable aldosteronism is associated with severe hypertension in early childhood
2001
Deletion Hybrid Genes, due to Unequal Crossing Over betweenCYP11B1(11β-Hydroxylase) andCYP11B2(Aldosterone Synthase) Cause Steroid 11β-Hydroxylase Deficiency and Congenital Adrenal Hyperplasia1
2001
Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism
2002
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
Familial hyperaldosteronism type II is linked to the chromosome 7p22 region but also shows predicted heterogeneity
2005
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
1992 StandoutNature
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
1997 StandoutNobel
Primary Hyperaldosteronism in Essential Hypertensives: Prevalence, Biochemical Profile, and Molecular Biology1
2000
Microarray, qPCR, andKCNJ5Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors
2012
Genetic Susceptibility for Human Familial Essential Hypertension in a Region of Homology with Blood Pressure Linkage on Rat Chromosome 10
1997 StandoutNobel
Primary aldosteronism
1995
Wnt/β-Catenin Signaling and Disease
2012 Standout
Mineralocorticoid hypertension
1994
RecombinantCYP11BGenes Encode Enzymes that Can Catalyze Conversion of 11-Deoxycortisol to Cortisol, 18-Hydroxycortisol, and 18-Oxocortisol1
1998
CD36 is a sensor of diacylglycerides
2005 StandoutNatureNobel
TRP channels as cellular sensors
2003 StandoutNature
A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.
1997
Linking Colorectal Cancer to Wnt Signaling
2000
A Novel Form of Human Mendelian Hypertension Featuring Nonglucocorticoid-Remediable Aldosteronism
2008
Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways
1999
Male–female differences in fertility and blood pressure in ACE-deficient mice
1995 StandoutNatureNobel
A Drosophila APC tumour suppressor homologue functions in cellular adhesion
2002
Familial hyperaldosteronism
2001
Importance of quantitative genetic variations in the etiology of hypertension
2000 StandoutNobel
Somatic Inactivation of Pkd2 Results in Polycystic Kidney Disease
1998
Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 StandoutNobel
β-Catenin Mutations Are Frequent in Human Hepatocellular Carcinomas Associated with Hepatitis C Virus Infection
1999
Atherosclerosis
2000 StandoutNature
Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension
1992
Wnt signalling in stem cells and cancer
2005 StandoutNature
Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na–K–2CI cotransporter NKCC2
1996
Human hypertension caused by mutations in the kidney isozyme of 11β–hydroxysteroid dehydrogenase
1995
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
THE GENETICS, PATHOPHYSIOLOGX, AND MANAGEMENT OF HUMAN DEFICIENCIES OF P450c17
2001
Siah-1 Mediates a Novel β-Catenin Degradation Pathway Linking p53 to the Adenomatous Polyposis Coli Protein
2001
Genome Duplications and Other Features in 12 Mb of DNA Sequence from Human Chromosome 16p and 16q
1999
A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure.
1993
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
1993 StandoutNobel
Molecular Genetics of Human Blood Pressure Variation
1996 Science
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Genetic Models of Human Vascular Disease
1995 StandoutNobel
Glucocorticoid-Remediable Aldosteronism
1999
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Estrogen receptor variant and hypertension in women.
1993
Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.
1992
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
The biochemical phenotypes of two inborn errors in the biosynthesis of aldosterone.
1992
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
2001 StandoutNobel
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Wnt signaling and cancer
2000 Standout
Negative Feedback Loop of Wnt Signaling through Upregulation of Conductin/Axin2 in Colorectal and Liver Tumors
2002
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
Inhibition of Adipogenesis by Wnt Signaling
2000 StandoutScience
Intracranial Aneurysm and Hemorrhagic Stroke in Glucocorticoid-remediable Aldosteronism
1998
Evaluation of the Dexamethasone Suppression Test for the Diagnosis of Glucocorticoid-Remediable Aldosteronism1
1997
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Evidence for a Gene Influencing Blood Pressure on Chromosome 17
2000
The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline
2016 Standout
Genetic Analysis of Aldosterone Synthase in Patients with Idiopathic Hyperaldosteronism1
1999
Captopril Suppression Versus Salt Loading in Confirming Primary Aldosteronism
2001
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner
1998 StandoutNobel
Genetic Dissection of Complex Traits
1994 StandoutScience
18-Hydroxycorticosterone, 18-Hydroxycortisol, and 18-Oxocortisol in the Diagnosis of Primary Aldosteronism and Its Subtypes
2012
Gene Targeting Approaches to Analyzing Hypertension
1999 StandoutNobel
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Measurement of Peripheral Plasma 18-Oxocortisol Can Discriminate Unilateral Adenoma From Bilateral Diseases in Patients With Primary Aldosteronism
2015
Genetic variation in P450c11AS in Chilean patients with low renin hypertension.
1996
Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.
1994 StandoutNobel
Beta-catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway.
1999
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Minireview: Primary Aldosteronism—Changing Concepts in Diagnosis and Treatment
2003
Uncompensated polyuria in a mouse model of Bartter's syndrome
2000 StandoutNobel
Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.
1995 StandoutNobel
Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5
2012
Reduced growth, abnormal kidney structure, and type 2 (AT 2 ) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT 1A and AT 1B receptors for angiotensin II
1998 StandoutNobel
Prevalence and Characteristics of Familial Hyperaldosteronism
2011
Genetic Study of Patients with Dexamethasone-Suppressible Aldosteronism without the Chimeric CYP11B1/CYP11B2 Gene
2001
Molecular phenotyping for analyzing subtle genetic effects in mice: Application to an angiotensinogen gene titration
2002 StandoutNobel
Works of Michael D. Powers being referenced
Hereditary hypertension caused by chimaeric gene duplications and ectopic expression of aldosterone synthase
1992
A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
1992 StandoutNature
Beta-catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas.
1999