Citation Impact
Citing Papers
Taking Cell-Matrix Adhesions to the Third Dimension
2001 StandoutScience
Recreation of the terminal events in physiological integrin activation
2010
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
2005 StandoutNature
Tests of the Extension and Deadbolt Models of Integrin Activation
2007
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
2008 StandoutNobel
The Novel S527F Mutation in the Integrin β3 Chain Induces a High Affinity αIIbβ3 Receptor by Hindering Adoption of the Bent Conformation
2009
Pleiotropic Coupling of G Protein-coupled Receptors to the Mitogen-activated Protein Kinase Cascade
1999 StandoutNobel
Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry
1987
Modulation of Integrin Activation by an Entropic Spring in the β-Knee
2010 StandoutNobel
Rapid Secretion of Interleukin-1β by Microvesicle Shedding
2001
Integrin Activation by R-ras
1996
Genetic effects on gene expression across human tissues
2017 StandoutNature
Differential Effects of Platelet-derived Growth Factor BB on p125 Focal Adhesion Kinase and Paxillin Tyrosine Phosphorylation and on Cell Migration in Rabbit Aortic Vascular Smooth Muscle Cells and Swiss 3T3 Fibroblasts
1995
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Mechanical control of integrin-mediated adhesion and signaling
2012
Are changes in integrin affinity and conformation overemphasized?
1998
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
The inner world of cell adhesion: integrin cytoplasmic domains
1994
Integrin modulating factor-1: A lipid that alters the function of leukocyte integrins
1992
Ligand Binding to Integrin αIIbβ3 Is Dependent on a MIDAS-like Domain in the β3 Subunit
1996
Dynamic control over cell adhesive properties using molecular-based surface engineering strategies
2009 StandoutNobel
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
2004
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Bi-directional signal transduction by integrin receptors
2000
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Relationships between Rap1b, Affinity Modulation of Integrin αIIbβ3, and the Actin Cytoskeleton
2002
Differential Regulation of Pyk2 and Focal Adhesion Kinase (FAK)
1998
Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
1994 StandoutNature
DANCE, a Novel Secreted RGD Protein Expressed in Developing, Atherosclerotic, and Balloon-injured Arteries
1999 StandoutNobel
The ATP-gated P2X1 Receptor Plays a Pivotal Role in Activation of Aspirin-treated Platelets by Thrombin and Epinephrine
2008 StandoutNobel
Suppression of Integrin Activation: A Novel Function of a Ras/Raf-Initiated MAP Kinase Pathway
1997
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
1993 StandoutNature
CD44 and Its Interaction with Extracellular Matrix
1993
Heterogeneity of fibrinogen receptor expression on platelets activated in normal plasma with ADP: analysis by flow cytometry
1989
Cell Migration: A Physically Integrated Molecular Process
1996 Standout
Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation
1990
An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.
1995
The Conserved Membrane-proximal Region of an Integrin Cytoplasmic Domain Specifies Ligand Binding Affinity
1995
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
2004 StandoutNature
Topography of Ligand-induced Binding Sites, Including a Novel Cation-sensitive Epitope (AP5) at the Amino Terminus, of the Human Integrin β3 Subunit
1995
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
Sensing the environment: a historical perspective on integrin signal transduction
2002
Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
2001
Integrin affinity modulation
1998
Coordinated Signaling through Both G12/13 and Gi Pathways Is Sufficient to Activate GPIIb/IIIa in Human Platelets
2002
Breaking the Integrin Hinge
1996
Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex
1992
Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration
2001
α2A-Adrenergic Receptor Stimulation Potentiates Calcium Release in Platelets by Modulating cAMP Levels
2000
Programmable Cell Adhesion Encoded by DNA Hybridization
2005 StandoutNobel
Cell adhesion in vascular biology. New insights into integrin-ligand interaction.
1997
Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP‐ and thrombin‐induced human platelet activation
2004 StandoutNobel
Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo
2015 StandoutNobel
Focal adhesion kinase and associated proteins
1994
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
1994 Standout
Two Signaling Mechanisms for Activation of αMβ2 Avidity in Polymorphonuclear Neutrophils
1998
Thrombspondin Acts via Integrin-associated Protein to Activate the Platelet Integrin αIIbβ3
1997
Phosphoinositide 3-Kinase Inhibition Spares Actin Assembly in Activating Platelets but Reverses Platelet Aggregation
1995
Integrins
2002 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)
1991
Lyn and Fgr Protein-tyrosine Kinases Prevent Apoptosis during Retinoic Acid-induced Granulocytic Differentiation of HL-60 Cells
1996 StandoutNobel
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation
2003 StandoutNobel
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
1998 StandoutNature
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
1998 StandoutNatureNobel
Biochemistry of Nitric Oxide and Its Redox-Activated Forms
1992 StandoutScience
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.
1995
A highly conserved sequence of the Arg-Gly-Asp-binding domain of the integrin beta 3 subunit is sensitive to stimulation
1991
Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.
1995
Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides.
1992
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Requirement for CD44 in Activated T Cell Extravasation into an Inflammatory Site
1997 StandoutScience
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP
2002 StandoutNobel
Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling
1993 StandoutNobel
Studies of Fibrinogen Binding to Platelets by Flow Cytometry: An Improved Method for Studies of Platelet Activation
1992 StandoutNobel
Long range propagation of conformational changes in integrin alpha IIb beta 3.
1993
FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING
1996 Standout
The GPIIb/IIIa (integrin αIIbβ3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend
2008
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
A conformation-dependent epitope of human platelet glycoprotein IIIa
1990
Multiple Grb2-Mediated Integrin-Stimulated Signaling Pathways to ERK2/Mitogen-Activated Protein Kinase: Summation of Both c-Src- and Focal Adhesion Kinase-Initiated Tyrosine Phosphorylation Events
1998
Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.
1990
Mutation of a ligand binding domain of beta 3 integrin. Integral role of oxygenated residues in alpha IIb beta 3 (GPIIb-IIIa) receptor function.
1994
Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils.
1994
Defects in secretion, aggregation, and thrombus formation in platelets from mice lacking Akt2
2004
A novel LFA-1 activation epitope maps to the I domain.
1993
Complementary Roles for Receptor Clustering and Conformational Change in the Adhesive and Signaling Functions of Integrin αIIbβ3
1998
Integrin cytoplasmic domains mediate inside-out signal transduction
1994
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene
1997 StandoutNobel
Potentiation of Thromboxane A2-induced Platelet Secretion by Gi Signaling through the Phosphoinositide-3 Kinase Pathway
2001
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Integrin Signaling
1999 StandoutScience
Function and Regulation of the β3 Integrins in Hemostasis and Vascular Biology
1995
The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases.
1995
Requirement for Generation of H 2 O 2 for Platelet-Derived Growth Factor Signal Transduction
1995 StandoutScience
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Studies with a monoclonal antibody against activated platelets: evidence that a secreted 53,000-molecular weight lysosome-like granule protein is exposed on the surface of activated platelets in the circulation
1987
Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins
1989 StandoutScience
Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.
1991
Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.
1990
Activation affects access to the platelet receptor for adhesive glycoproteins.
1986
Direct detection of activated platelets and platelet-derived microparticles in humans
1990
Effect of platelet activation on the conformation of the plasma membrane glycoprotein IIb-IIIa complex
1991
Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation
1997
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
2010 StandoutNobel
Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice.
1995 StandoutNobel
Structural and Biosynthetic Studies of the Granule Membrane Protein, GMP-140, from Human Platelets and Endothelial Cells
1989
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels
1997 StandoutNobel
Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells
1997
Distinct Activation States of α5β1 Integrin Show Differential Binding to RGD and Synergy Domains of Fibronectin
2002
Fibrinogen as a key regulator of inflammation in disease
2011
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Evidence for In Vivo Phosphorylation of the Grb2 SH2-Domain Binding Site on Focal Adhesion Kinase by Src-Family Protein-Tyrosine Kinases
1996
Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane
1989
Tyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrix
1998
Geometric Control of Cell Life and Death
1997 StandoutScience
A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.
1993
Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis
2010
Works of Michael Cunningham being referenced
Role of calcium and calpain in complement-induced vesiculation of the platelet plasma membrane and in the exposure of the platelet factor Va receptor
1990
Phosphoinositide 3-Kinase γ and p85/Phosphoinositide 3-Kinase in Platelets
1996
Reduced thiols and the effect of intravenous nitroglycerin on platelet aggregation
1988
Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.
1985
Adhesive ligand binding to integrin alpha IIb beta 3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK
1993
Regulation of glycoprotein IIb-IIIa receptor function studied with platelets permeabilized by the pore-forming complement proteins C5b-9.
1992
Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors.
1994