Citation Impact
Citing Papers
Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
2009
Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.
1977 StandoutNobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Synergistic cytotoxicity of the ribonucleotide reductase inhibitor didox (3,4-dihydroxy-benzohydroxamic acid) and the alkylating agent carmustine (BCNU) in 9L rat gliosarcoma cells and DAOY human medulloblastoma cells
2004
Phase I trial of paclitaxel in children with refractory solid tumors: a Pediatric Oncology Group Study.
1993
A Polymer-Based, Paclitaxel-Eluting Stent in Patients with Coronary Artery Disease
2004 Standout
Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans.
1995 Standout
Dynamic Covalent Chemistry
2002 StandoutNobel
Taxol administered as a 120 hour infusion
1992
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
EMT and Dissemination Precede Pancreatic Tumor Formation
2012 Standout
A Randomized Trial of Surgery in the Treatment of Single Metastases to the Brain
1990 Standout
Inactivation of the DNA-Repair GeneMGMTand the Clinical Response of Gliomas to Alkylating Agents
2000 Standout
Multidrug resistance (mdr) genes in human cancer
1991
Paclitaxel (Taxol)
1995 Standout
Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.
1993
Personalized Dosing of Cyclophosphamide in the Total Body Irradiation–Cyclophosphamide Conditioning Regimen: A Phase II Trial in Patients With Hematologic Malignancy
2009
Steady-state plasma concentrations and effects of taxol for a 250 mg/m2 dose in combination with granulocyte-colony stimulating factor in patients with ovarian cancer
1993
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
A New Equation to Estimate Glomerular Filtration Rate
2009 Standout
Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumors.
1994
Synergism through direct covalent bonding between agents: A strategy for rational design of chemotherapeutic combinations
1990
Hematopoietic Reconstitution in a Patient with Fanconi's Anemia by Means of Umbilical-Cord Blood from an HLA-Identical Sibling
1989 Standout
Taxol inhibits neointimal smooth muscle cell accumulation after angioplasty in the rat.
1995
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
2010
Malignant Gliomas in Adults
2008 Standout
Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation
2010 Standout
Paclitaxel in doxorubicin-refractory or mitoxantrone-refractory breast cancer: a phase I/II trial of 96-hour infusion.
1994
Hematopoietic Stem-Cell Transplantation
2006 Standout
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
Morphological Characterization of Polyanhydride Biodegradable Implant Gliadel® During in Vitro and in Vivo Erosion Using Scanning Electron Microscopy
1996
EMT: 2016
2016 Standout
A phase II study of taxol in patients with malignant melanoma
1991
What We Talk About When We Talk About Fat
2014 Standout
Phase I trial of 3-hour infusion of paclitaxel with or without granulocyte colony-stimulating factor in patients with advanced cancer.
1994
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
2007 Standout
DNA alkylation by the haloethylnitrosoureas: Nature of modifications produced and their enzymatic repair or removal
1990
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry
2006 StandoutNobel
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell
2001 Standout
Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
2012
soluble form of CD4 (T4) protein inhibits AIDS virus infection
1988 StandoutNatureNobel
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue
2012
Underrepresentation of Patients 65 Years of Age or Older in Cancer-Treatment Trials
1999 Standout
Cancer of the Ovary
2004 Standout
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
2009
Role of glutathione in the in vitro synergism between 4-hydroperoxy-cyclophosphamide and cisplatin in leukemia cell lines.
1991
Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation
2003
Chemotherapy of brain metastases: Current status
1984
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
1978
In Situ Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications
2004 StandoutNobel
Cyclophosphamide cystitis—Identification of acrolein as the causative agent
1979
From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions
2011 StandoutNobel
DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas.
1980 StandoutNobel
Role of aldehyde dehydrogenase in the protection of hematopoietic progenitor cells from 4-hydroperoxycyclophosphamide by interleukin 1 beta and tumor necrosis factor.
1992
New Findings on Breast Cancer Stem Cells: A Review
2015
DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells
1980 StandoutNatureNobel
Characterization of Cells with a High Aldehyde Dehydrogenase Activity from Cord Blood and Acute Myeloid Leukemia Samples
2005
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Reaction of 1,3-bis(2-chloroethyl)-1-nitrosourea with synthetic polynucleotides
1975
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
In Vitro Effect of Cyclophosphamide Metabolites on Chromosomes of Fanconi Anaemia Patients
1980
Interaction of N,N',N''-triethylenethiophosphoramide and N,N',N''-triethylenephosphoramide with cellular DNA.
1991
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Zanvil Alexander Cohn 1926-1993.
1994 StandoutNobel
Treatment of Disseminated Germ-Cell Tumors with Cisplatin, Bleomycin, and either Vinblastine or Etoposide
1987 Standout
Elimination of acute myelogenous leukemic cells from marrow and tumor suspensions in the rat with 4-hydroperoxycyclophosphamide
1980
Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma
2008
Cancer, Clinical Pharmacology, and Aging
1987
Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis
1981
Cross-linking of DNA induced by chloroethyinitrosourea is prevented by O6-methyiguanine-DNA methyttransferase
1983 StandoutNobel
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of Metastasis
2010
Mechanism of action of 2-haloethylnitrosoureas on DNA and its relation to their antileukemic properties
1978
A structural basis for a phosphoramide mustard-induced DNA interstrand cross-link at 5'-d(GAC).
1995 StandoutNobel
Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity
2004
Characterization of mouse lymphohematopoietic stem cells lacking spleen colony-forming activity
1996
In Situ Selection of Lead Compounds by Click Chemistry: Target-Guided Optimization of Acetylcholinesterase Inhibitors
2005 StandoutNobel
Review of the use of marrow transplantation in the treatment of non-Hodgkin's lymphoma.
1983 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Requirement of Vascular Integrin α v β 3 for Angiogenesis
1994 StandoutScience
Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic Cancer
1985 Standout
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Subtractive immunization yields monoclonal antibodies that specifically inhibit metastasis
1993
Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
2005
The significance of DNA cross-linking to cis-diamminedichloroplatinum(II)-induced cytotoxicity in sensitive and resistant lines of murine leukemia L1210 cells
1982
Relationship between Human T Cell Functional Heterogeneity and Human T Cell Surface Molecules
1983
The In Vitro Generation of Effector Lymphocytes and Their Employment in Tumor Immunotherapy
1983
Ifosfamide in refractory male germ cell tumors.
1986
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.
1985
Drug Prescribing in Renal Failure: Dosing Guidelines for Adults.
1988
Works of Michael Colvin being referenced
Clinical Pharmacokinetics of Cyclophosphamide
1979
Enzymatic mechanisms of resistance to alkylating agents in tumor cells and normal tissues
1988
Generation of Dual Resistance to 4-Hydroperoxycyclophosphamide and Methotrexate by Retroviral Transfer of the Human Aldehyde Dehydrogenase Class 1 Gene and a Mutated Dihydrofolate Reductase Gene
2001
A chemical basis for the antitumor activity of chloroethylnitrosoureas
1976
High-performance liquid chromatographic assay for taxol in human plasma and urine and pharmacokinetics in a phase I trial.
1987
Identification of aldophosphamide as a metabolite of cyclophosphamide in vitro and in vivo in humans.
1977
Interstitial Drug Therapy for Brain Tumors: A Case Study
1990
Comparative Effects of Cyclophosphamide, Isophosphamide, 4-Methylcyclophosphamide, and Phosphoramide Mustard on Murine Hematopoietic and Immunocompetent Cells<xref ref-type="fn" rid="FN2">2</xref>
1979
Role for aldehyde dehydrogenase in survival of progenitors for murine blast cell colonies after treatment with 4-hydroperoxycyclophosphamide in vitro.
1988
In vitro effects of 4-hydroperoxycyclophosphamide on human immunoregulatory T subset function. I. Selective effects on lymphocyte function in T-B cell collaboration.
1982
Comparative cytotoxicity of various drug combinations for human leukemic cells and normal hematopoietic precursors.
1987
Transport of melphalan by sensitive and resistant L1210 cells.
1980
The quantitation by gas chromatography-chemical ionisation-mass spectrometry of cyclophosphamide, phosphoramide mustard and nornitrogen mustard in the plasma and urine of patients receiving cyclophosphamide therapy
1978
Intensive cyclophosphamide (NSC-26271) therapy for solid tumors.
1975
Synergistic effect of 4-hydroperoxycyclophosphamide and etoposide on a human promyelocytic leukemia cell line (HL-60) demonstrated by computer analysis.
1985
Chemistry of nitrosoureas. Decomposition of 1,3-bis(threo-3-chloro-2-butyl)-1-nitrosourea and 1,3-bis(erythro-3-chloro-2-butyl)-1-nitrosourea
1977
Cyclophosphamide plasma and cerebrospinal fluid kinetics with and without dimethyl sulfoxide
1982
Decomposition of BCNU (1,3-Bis(2-chloroethyl)-1-nitrosourea) in aqueous solution
1974
Alkylating properties of phosphoramide mustard.
1976
Pharmacology of cyclophosphamide and metabolites.
1981
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells
2006
A biologically active metabolite of cyclophosphamide.
1973
Chemistry of nitrosoureas. Decomposition of deuterated 1,3-bis(2-chloroethyl)-1-nitrosourea
1976
Marrow transplanation in man following cyclophosphamide.
1971