Citation Impact
Citing Papers
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
2004 StandoutScience
Regulation of growth differentiation factor 15 expression by intracellular iron
2008 StandoutNobel
Soft corrugated channel with synergistic exclusive discrimination gating for CO2 recognition in gas mixture
2023 StandoutNobel
Ionic liquid-assisted carboxylation of amines by CO2: a mechanistic consideration
2011
Recent applications of protein crystallography and structure-guided drug design
2005
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Hereditary Hemochromatosis — A New Look at an Old Disease
2004
Opioid Diketopiperazines: Synthesis and Activity of a Prototypic Class of Opioid Antagonists
1997
Synthesis and Properties of Allenic Natural Products and Pharmaceuticals
2004 Standout
Host Genetic Factors and Antiviral Immune Responses to Hepatitis C Virus
2008
Peptidomimetics derived from natural products
1993
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral Therapy
1997 Standout
Calculation of solvation and binding free energy differences between VX-478 and its analogs by free energy perturbation and AMSOL methods
1996
Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine
1995
Protein folding and misfolding
2003 StandoutNature
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
1995 Nature
Hematopoietic Stem-Cell Transplantation
2006 Standout
Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors
2005
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors
2004
Features and development of Coot
2010 Standout
Molecular Recognition in Chemical and Biological Systems
2015
Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity
2006
Improved Cyclopropanation Activity of Histidine‐Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran
2014 StandoutNobel
Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry
2006 StandoutNobel
Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling
2006
Structure-based development of target-specific compound libraries
2006
Molecular Mechanisms of Amyloidosis
2003 Standout
Outside the Safe Operating Space of the Planetary Boundary for Novel Entities
2022 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Bioorganometallic Chemistry of Ferrocene
2004 Standout
Efficient and Selective Palladium‐Catalysed C‐3 Urea Couplings to 3,5‐Dichloro‐2(1H)‐pyrazinones
2015
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
2010 Standout
Novel asymmetric synthesis of a bicyclo[3.1.0]hexane derivative by an efficient retro-diels-alder strategy
1996
Synthesis of ureas in the bio-alternative solvent Cyrene
2017
Peptidomimetics—Tailored Enzyme Inhibitors
1994
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
Water as an Active Constituent in Cell Biology
2007 Standout
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
The global threat from plastic pollution
2021 StandoutScience
Development of a Large-Scale Process for an HIV Protease Inhibitor
1997
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Functionalized erythro N-protected α-amino epoxides. Stereocontrolled synthesis and biological activity
1997
Catalysis for the Valorization of Exhaust Carbon: from CO2to Chemicals, Materials, and Fuels. Technological Use of CO2
2013 Standout
New dipeptide isosteres useful for the inhibition of HIV-1 protease
1994
Synthesis and biological evaluation of a series of HIV-1 protease inhibitors
1993
Synthese und Eigenschaften allenischer Natur‐ und Wirkstoffe
2004
Crystal structures of HIV-1 protease-inhibitor complexes
1993
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
The hemochromatosis C282Y allele: a risk factor for hepatic veno-occlusive disease after hematopoietic stem cell transplantation
2005
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
2005 Standout
The discovery of the new haemochromatosis gene
2003
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
The Cation−π Interaction
1997 Standout
Simple and Versatile Synthesis of Optically Active 1,2‐Amino Alcohols by Grignard Addition toN,O‐Dibenzylglyceraldimine and ‐lactaldimine
1994
Stereoselective Cyclopropanation Reactions
2003 Standout
Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450
1996
Green and Sustainable Solvents in Chemical Processes
2018 Standout
A Field Guide to Foldamers
2001 Standout
Additions of Organometallic Reagents to CN Bonds: Reactivity and Selectivity
1998 Standout
ITERATIVE PROTEIN STRUCTURE-BASED DRUG DESIGN AND SYNTHESIS OF HIV PROTEASE INHIBITORS
1995
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
An Alternative Enantioselective Synthesis of (+)-Tricyclodecadienone
1997 StandoutNobel
Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents
2008 StandoutNobel
Microwave-assisted synthesis utilizing supported reagents: a rapid and versatile synthesis of 1,5-diarylpyrazoles
2006
Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors
1994 Science
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.
1995
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Chiral Allenes via Alkynylogous Mukaiyama Aldol Reaction
2016 StandoutNobel
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
Transition Metal Catalyzed Cycloisomerizations of 1,n-Allenynes and -Allenenes
2011 Standout
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Nonpeptide HIV protease inhibitors designed to replace a bound water
1993
Some Typical Advances in the Synthetic Applications of Allenes
2005 Standout
Tipranavir (PNU-140690): A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class
1998
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Stereocontrolled sequential functionalization in acyclic systems by exploiting internal 1,2-asymmetric induction — generation of symmetry-related polyamino alcohol motifs
1996
Works of Michael Clare being referenced
Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex
2003
Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere
1995
HLA class I allelic diversity and progression of fibrosis in patients with chronic hepatitis C
2006
Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei
2013
Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y
2002
Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes
1991
Enkephalin Analogs as Systemically Active Antinociceptive Agents: O- and N-Alkylated Derivatives of the Dipeptide Amide L-2,6-Dimethyltyrosyl-N-(3-phenylpropyl)-D-alaninamide
1994
Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere
1993
Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis
1999
A stereocontrolled synthesis of a novel prostacyclin analog “allene-carbacyclin”. Application of molecular mechanics calculations to organic synthesis.
1987
SC-52151, a novel inhibitor of the human immunodeficiency virus protease
1995
Studies in the synthesis of the thromboxane receptor antagonist EP 092 and its enantiomers
1990
Seafloor microplastic hotspots controlled by deep-sea circulation
2020 Science
Dispersion, Accumulation, and the Ultimate Fate of Microplastics in Deep-Marine Environments: A Review and Future Directions
2019
Design, Parallel Synthesis, and Crystal Structures of Pyrazinone Antithrombotics as Selective Inhibitors of the Tissue Factor VIIa Complex
2003
HIV protease: Structure-based design
1993