Standout Papers
Citation Impact
Citing Papers
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis
2008
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
The impact of rare and low-frequency genetic variants in common disease
2017
Epigenetic influence of environmentally neurotoxic metals
2020
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
2000 StandoutNobel
Genetic effects on gene expression across human tissues
2017 StandoutNature
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
2001 StandoutNobel
Hepatocellular carcinoma
2018 Standout
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Deep convolutional models improve predictions of macaque V1 responses to natural images
2019
The genetics of folate metabolism and maternal risk of birth of a child with Down syndrome and associated congenital heart defects
2015
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2
1997 Standout
Choosing anticancer drug targets in the postgenomic era
1999 StandoutNobel
Unsupervised deep learning identifies semantic disentanglement in single inferotemporal face patch neurons
2021 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The role of transforming growth factor Β in glioma progression
1998
Protease inhibition as new therapeutic strategy for GI diseases
2016
Rare-Variant Association Analysis: Study Designs and Statistical Tests
2014
Deep Neural Networks Rival the Representation of Primate IT Cortex for Core Visual Object Recognition
2014
Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
2018
Gene therapy for cancer
1994
Deep Neural Networks Reveal a Gradient in the Complexity of Neural Representations across the Ventral Stream
2015
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers
1997
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Fluorescent resonance energy transfer: A tool for probing molecular cell–biomaterial interactions in three dimensions
2007
Mechanisms of HBV-induced hepatocellular carcinoma
2016
Distinct Sets of Genetic Alterations in Melanoma
2005 Standout
Revealing the human mucinome
2022 StandoutNobel
Genetic profiling of hepatocellular carcinoma using next-generation sequencing
2016
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Oncogene amplification in solid tumors
1999
Exploiting different ways to die: Figure 1.
2004
Apoptosis
2002 Standout
TGFβ in Cancer
2008 Standout
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma
2015
Deep learning
2015 StandoutNatureNobel
A functionally inactive p53 protein interatocarcinoma cells is activated by either DNA damage or cellular differentiation
1996
p63 is a p53 homologue required for limb and epidermal morphogenesis
1999 StandoutNature
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The Emerging p53 Gene Family
1999 StandoutNobel
p53 expression and risk factors for cutaneous melanoma: A case-control study
1998
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
A Model of V4 Shape Selectivity and Invariance
2007
Crosstalk at the mucosal border: importance of the gut microenvironment in IBS
2014
Identifying natural images from human brain activity
2008 Nature
Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution
2015 StandoutNobel
Meta-analysis methods for genome-wide association studies and beyond
2013
Functional and genetic deconstruction of the cellular origin in liver cancer
2015
Albumin-bound paclitaxel: a next-generation taxane
2006
Expression of p53 in Saos-2 osteosarcoma cells induces apoptosis which can be inhibited by Bcl-2 or the adenovirus E1B-55 kDa protein.
1996
Down Syndrome
2020 Standout
Hepatocellular Carcinoma
2019 Standout
Likelihood Models of Somatic Mutation and Codon Substitution in Cancer Genes
2003
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Human TAFII31 protein is a transcriptional coactivator of the p53 protein.
1995
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
1994 StandoutScience
Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration
2015 Standout
Unsupervised learning by competing hidden units
2019 StandoutNobel
Predicting Human Brain Activity Associated with the Meanings of Nouns
2008 StandoutScience
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
Nanoparticles in Photodynamic Therapy
2015 Standout
A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control
2001
Preferential Formation of Benzo[ a ]pyrene Adducts at Lung Cancer Mutational Hotspots in P53
1996 Science
Nanostructured Plasmonic Sensors
2008 Standout
Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
2000 StandoutScience
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy
1999 Science
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
The N-Terminal Domain of p73 Interacts with the CH1 Domain of p300/CREB Binding Protein and Mediates Transcriptional Activation and Apoptosis
2000
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Identifying Causal Variants at Loci with Multiple Signals of Association
2014
Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
1998 Standout
Blockage by Adenovirus E4orf6 of Transcriptional Activation by the p53 Tumor Suppressor
1996 Science
The CDK7-cycH-p36 Complex of Transcription Factor IIH Phosphorylates p53, Enhancing Its Sequence-Specific DNA Binding Activity In Vitro
1997
Neuronal Dynamics: From Single Neurons to Networks and Models of Cognition
2014
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Another p53 Doppelgänger?
1998 StandoutScienceNobel
Works of Michael C. Wu being referenced
Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test
2011 Standout
Fecal Protease Activity Is Associated with Compositional Alterations in the Intestinal Microbiota
2013
Identification of driver genes in hepatocellular carcinoma by exome sequencing
2013
The Spectrum of Mutations at the p53 Locus
1995
Nonlinear V1 responses to natural scenes revealed by neural network analysis
2004
The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis
1994
Powerful SNP-Set Analysis for Case-Control Genome-wide Association Studies
2010
Development and validation of a prioritization rule for obtaining an immediate 12-lead electrocardiogram in the emergency department to identify ST-elevation myocardial infarction
2012
Optimal tests for rare variant effects in sequencing association studies
2012
Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome
2010
COMPLETE FUNCTIONAL CHARACTERIZATION OF SENSORY NEURONS BY SYSTEM IDENTIFICATION
2006
Endogenous Osteonectin/SPARC/BM-40 Expression Inhibits MDA-MB-231 Breast Cancer Cell Metastasis
2005
The p53 tumor suppressor gene.
1994
Matrix cell adhesion activation by non-adhesion proteins
2005
Arsenic and the Epigenome: Interindividual Differences in Arsenic Metabolism Related to Distinct Patterns of DNA Methylation
2013