Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
(1,3)-β-Glucans Activate Both Dectin-1 and NLRP3 Inflammasome in Human Macrophages
2010
Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome
2009
Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal β-Glucan
2009
Fungal Zymosan and Mannan Activate the Cryopyrin Inflammasome
2009
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO
2010
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)
2015 StandoutNobel
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
2018
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
2013
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Inflammasome Inhibition as a Pathogenic Stealth Mechanism
2010
Induction and Evasion of Innate Antiviral Responses by Hepatitis C Virus
2010
The Role of Syk/CARD9‐Coupled C‐Type Lectin Receptors in Immunity to Mycobacterium tuberculosis Infections
2010
Necroptosis and its role in inflammation
2015 StandoutNature
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
2013 StandoutNature
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
2011 Standout
Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent Mechanisms
2011
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
2008
Nlrp3: An immune sensor of cellular stress and infection
2010
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase
2010
Activation and regulation of the inflammasomes
2013 Standout
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
2010 Standout
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity
2011
Pattern Recognition Receptors and Inflammation
2010 Standout
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
2008
Effector functions of NLRs in the intestine: innate sensing, cell death, and disease
2012
Severe Sepsis and Septic Shock
2013 Standout
Lessons from the inflammasome: a molecular sentry linking Candida and Crohn's disease
2010
Nonresolving Inflammation
2010 Standout
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
2008
Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense
2011
Influenza virus activates inflammasomes via its intracellular M2 ion channel
2010
Sensing Cytoplasmic Danger Signals by the Inflammasome
2010
Mitochondrial anti-viral immunity
2012
Central roles of NLRs and inflammasomes in viral infection
2010
Immune Signaling by RIG-I-like Receptors
2011
Regulation of the innate immune response by threonine-phosphatase of Eyes absent
2009 Nature
A long-awaited merger of the pathways mediating host defence and programmed cell death
2014
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
Recognition of yeast nucleic acids triggers a host‐protective type I interferon response
2011
Caspase Functions in Cell Death and Disease
2013 Standout
The Inflammasomes: Molecular Effectors of Host Resistance Against Bacterial, Viral, Parasitic, and Fungal Infections
2011
Innate immune mechanisms for recognition and uptake of Candida species
2010
RIG-I RNA Helicase Activation of IRF3 Transcription Factor Is Negatively Regulated by Caspase-8-Mediated Cleavage of the RIP1 Protein
2011
The role of Dectin-1 in the host defence against fungal infections
2011
Signalling through C-type lectin receptors: shaping immune responses
2009
Death receptor signal transducers: nodes of coordination in immune signaling networks
2009
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
The E3 Ubiquitin Ligase Mind Bomb-2 (MIB2) Protein Controls B-cell CLL/Lymphoma 10 (BCL10)-dependent NF-κB Activation
2011
Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
2009
The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants
2010
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
2011 Nature
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
2014
The Therapeutic Potential of Modifying Inflammasomes and NOD-Like Receptors
2013
An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans
2009
Molecular Mechanism of NLRP3 Inflammasome Activation
2010
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
2009
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
2013
Inflammasomes as microbial sensors
2010
Immunity to fungal infections
2011 Standout
Rift Valley fever virus infection induces activation of the NLRP3 inflammasome
2013
The SYK tyrosine kinase: a crucial player in diverse biological functions
2010
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
2012
Regulation of inflammasome activity
2010
The inflammasomes: mechanisms of activation and function
2010
IFI16 is an innate immune sensor for intracellular DNA
2010
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Innate Immune Receptors
2016
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
2009 StandoutNature
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
2011
Inflammasomes in health and disease
2012 StandoutNature
Regulation of the Antimicrobial Response by NLR Proteins
2011
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs
2009
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1β Secretion through the NLRP3 Inflammasome In Vitro
2011
MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3
2015
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
The adaptor molecule CARD9 is essential for tuberculosis control
2010
Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1
2012
The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
2011
JAK2 activation by growth hormone and other cytokines
2015
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
2011
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
Post-translational regulation of inflammasomes
2016
Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors
2008
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella
2010
The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
2010 Science
Viral evasion and subversion of pattern-recognition receptor signalling
2008
Protein kinase D at the Golgi controls NLRP3 inflammasome activation
2017
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Modulation of Inflammasome Pathways by Bacterial and Viral Pathogens
2011
Cellular localization of NLRP3 inflammasome
2013
Intracellular sensing of microbes and danger signals by the inflammasomes
2011
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
A Virological View of Innate Immune Recognition
2012
Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses
2015
Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification
2010
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
2014
A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects
2017
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Inflammasomes and Their Roles in Health and Disease
2012
Human NLRP3 inflammasome senses multiple types of bacterial RNAs
2014
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Cutting Edge: Nlrp10 Is Essential for Protective Antifungal Adaptive Immunity against Candida albicans
2012
The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis
2010
Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
2015
Fungal attacks on mammalian hosts: pathogen elimination requires sensing and tasting
2010
Pathogenic Vibrio Activate NLRP3 Inflammasome via Cytotoxins and TLR/Nucleotide-Binding Oligomerization Domain-Mediated NF-κB Signaling
2010
RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8 + T cells
2015 Science
Therapeutic cancer vaccines
2015
Interferon-β Therapy Against EAE Is Effective Only When Development of the Disease Depends on the NLRP3 Inflammasome
2012
Innate immunity to virus infection
2008
Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by Candida albicans Hyphae
2019
Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
2010
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
TLR Agonists Stimulate Nlrp3-Dependent IL-1β Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo
2012
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Michael Bscheider being referenced
RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade
2019
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
2009
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
2009 Nature
TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
2008
Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease
2014