Citation Impact
Citing Papers
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas
2008
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
2010
Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice
2008
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy
2002 Nature
Up-Regulation of Glial Fibrillary Acidic Protein in Response to Retinal Injury: Its Potential Role in Glial Remodeling and a Comparison to Vimentin Expression
2003
Synthesis, and Cytotoxic Activity of Nind-Alkoxy Derivatives of Antibiotic Arcyriarubin and Dechloro-rebeccamycin Aglycon.
2002
Structural basis of preinitiation complex assembly on human Pol II promoters
2000
A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17
2006
The remarkable metal-catalysed olefin metathesis reaction
2007 StandoutNature
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
2005
Yeast TAFII145 Functions as a Core Promoter Selectivity Factor, Not a General Coactivator
1997
Molecular cloning of Drosophila TFIID subunits
1994 Nature
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
2009 Standout
Efficient palladium-catalyzed synthesis of 3-aryl-4-indolylmaleimides
2008
Antisense RNA‐mediated transcriptional attenuation: an in vitro study of plasmid pT181
2000
Synthesis of bisindolylmaleimides using a palladium catalyzed cross-coupling reaction
1998
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication
1999
An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress
2003 Standout
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
The immunology of stroke: from mechanisms to translation
2011 Standout
Synthesis of new aza-analogs of staurosporine, K-252a and rebeccamycin by nucleophilic opening of C2-symmetric bis-aziridines
2008
Synthesis and biological evaluation of novel oxophenylarcyriaflavins as potential anticancer agents
2008
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Can molecules explain long-term potentiation?
1999
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
The general transcription factors of RNA polymerase II.
1996
Studies on cyclin-dependent kinase inhibitors: indolo-[2,3-a]pyrrolo[3,4-c]carbazoles versus bis-indolylmaleimides
2003
Evaluation of alternative approaches for the synthesis of macrocyclic bisindolylmaleimides
2004
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes
2011
Toll-like receptor signaling in endogenous neuroprotection and stroke
2008
Live Astrocytes Visualized by Green Fluorescent Protein in Transgenic Mice
1997
Interpreting cDNA sequences: Some insights from studies on translation
1996
The synthesis of bioactive indolocarbazoles related to K-252a
2005
Optogenetics in Neural Systems
2011 Standout
Noise in a minimal regulatory network: plasmid copy number control
2001
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Transcription Activation via Enhanced Preinitiation Complex Assembly in a Human Cell-Free System Lacking TAFIIs
1998
Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division
2008
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
New Synthesis of KT5823 Indolocarbazole Aglycone
2000
Benzannulation reactions of Fischer carbene complexes for the synthesis of indolocarbazoles
2001
Multileveled Selection on Plasmid Replication
2002
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID.
1992
Practical synthesis of indolopyrrolocarbazoles
1996
TNFR1 Upregulation Mediates Tolerance after Brain Ischemic Preconditioning
2005
Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.
1995 StandoutNobel
Detection of targeted GFP - Hox gene fusions during mouse embryogenesis
1998 StandoutNobel
Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms.
1993 StandoutNobel
Multiplexed RNA structure characterization with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)
2011 StandoutNobel
Synthesis of Granulatimide Positional Analogues.
2003
Initiation of eukaryotic messenger RNA synthesis.
1991
Synthesis of the indolo[2,3-a]carbazole natural products staurosporinone and arcyriaflavin B
1990
Novel indolocarbazole protein kinase c inhibitors with improved biochemical and physicochemical properties
1995
A facile synthesis of staurosporine aglycone
1994
The role of general initiation factors in transcription by RNA polymerase II
1996
Oxidative cyclisations with palladium acetate. A short synthesis of staurosporine aglycone.
1993
Staurosporine and ent-Staurosporine: The First Total Syntheses, Prospects for a Regioselective Approach, and Activity Profiles1
1996
Synthesis of 4-substituted 3-(indol-3-yl)maleimides and azepines with annelated indole and maleimide nuclei
2005
One-Pot Synthesis of 2-Substituted Indoles from 2-Aminobenzyl Phosphonium Salts. A Formal Total Synthesis of Arcyriacyanin A
2008
Inhibition of Reactive Astrocytes with Fluorocitrate Retards Neurovascular Remodeling and Recovery after Focal Cerebral Ischemia in Mice
2009
Synthesis of Rebeccamycin and 11-Dechlororebeccamycin
1999
Crystal structure of yeast TATA-binding protein and model for interaction with DNA.
1993 StandoutNobel
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
The histone fold: evolutionary questions.
1995 StandoutNobel
(Peri)vascular production and action of pro-inflammatory cytokines in brain pathology
2006
Molecular Matchmakers
1993 StandoutScienceNobel
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Synthesis and cyclisation of didemnimide C and its imidazol-1-yl isomer
1998
Stochastic Gene Expression in a Single Cell
2002 StandoutScience
Inverse electron-demand Diels–Alder chemistry in the synthesis of a regioselectively protected analogue of the staurosporine aglycone
2001
An analysis of vertebrate mRNA sequences: intimations of translational control.
1991 Standout
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
2001 Standout
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
A New, Efficient Method for the Synthesis of Bisindolylmaleimides
1998
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Synthesis of naphthopyrrolo[3,4-c]carbazoles
2001
Synthesis and Biological Evaluation of Novel Phenylcarbazoles as Potential Anticancer Agents
2005
CSPα-deficiency causes massive and rapid photoreceptor degeneration
2006 StandoutNobel
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
1991 Standout
Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex
2012 StandoutNobel
Regiospecific Synthesis of Mono-N-substituted Indolopyrrolocarbazoles
2005
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Mechanism of assembly of the RNA polymerase II preinitiation complex. Transcription factors delta and epsilon promote stable binding of the transcription apparatus to the initiator element.
1992
First efficient synthesis of novel oxophenyl-arcyriaflavin analogs
2005
Rebeccamycin analogues as anti-cancer agents
2003
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Construction of Carbocyclic Ring of Indoles Using Ruthenium-Catalyzed Ring-Closing Olefin Metathesis
2011
Five Rules for the Evolution of Cooperation
2006 StandoutScience
Mediator protein mutations that selectively abolish activated transcription
1999 StandoutNobel
Yeast RNA polymerase II initiation factor e: isolation and identification as the functional counterpart of human transcription factor IIB.
1992 StandoutNobel
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Structure−Activity Relationships in a Series of Substituted Indolocarbazoles: Topoisomerase I and Protein Kinase C Inhibition and Antitumoral and Antimicrobial Properties
1996
A convenient synthesis of bisindolyl- and indolylaryl maleic anhydrides
1990
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID.
1993
Hexafunctionalized Borromeates Using Olefin Cross Metathesis
2007 StandoutNobel
Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation
2005 StandoutNobel
Electrophilic substitution and cyclization of 2,2′‐bis(N‐methylindolyl): A simple access to potential protein kinase C inhibitor
1994
Identification of human TFIID components and direct interaction between a 250-kDa polypeptide and the TATA box-binding protein (TFIID tau).
1992
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Works of Michael Brenner being referenced
Analysis of a Segment of the Human Glial Fibrillary Acidic Protein Gene That Directs Astrocyte‐Specific Transcription
1993
Characterization of human cDNA and genomic clones for glial fibrillary acidic protein
1990
A downstream initiation element required for efficient TATA box binding and in vitro function of TFIID
1990 Nature
Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease
2001
Structure and Transcriptional Regulation of the GFAP Gene
1994
Differential cellular expression of tumor necrosis factor-α and Type I tumor necrosis factor receptor after transient global forebrain ischemia
2001
Enhanced hippocampal neurodegeneration after traumatic or kainate excitotoxicity in GFAP-null mice
2006
hGFAP‐cre transgenic mice for manipulation of glial and neuronal function in vivo
2001
ICP Monitoring Following Bilateral Carotid Occlusion in GFAP-Null Mice
2002
Quantitation of ColE1-encoded replication elements.
1991
Total syntheses of the slime mold alkaloid arcyriacyanin A
1997
Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice.
1998
GFAP Transgenic Mice
1996
Synthesis of arcyriarubin b and related bisindolylmaleimides
1988
Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology.
1996
GFAP promoter directs astrocyte-specific expression in transgenic mice
1994
Multiple interacting sites regulate astrocyte-specific transcription of the human gene for glial fibrillary acidic protein.
1991
Global Forebrain Ischemia Results in Differential Cellular Expression of Interleukin-1β (IL-1β) and its Receptor at mRNA and Protein Level
1997
An RNA polymerase II promoter containing sequences upstream and downstream from the RNA startpoint that direct initiation of transcription from the same site.
1990
Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation
1998
First Scale-Up to Production Scale of a Ring Closing Metathesis Reaction Forming a 15-Membered Macrocycle as a Precursor of an Active Pharmaceutical Ingredient
2005
TNF-α pretreatment prevents subsequent activation of cultured brain cells with TNF-α and hypoxia via ceramide
1999