Citation Impact
Citing Papers
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole
2006
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance
2006
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Amino acids that specify structure through hydrophobic clustering and histidine-aromatic interactions lead to biologically active peptidomimetics
1994
Halogen bonding in solution: thermodynamics and applications
2012
Molecular, pharmacological and functional diversity of 5-HT receptors
2002 Standout
Pharmacological Profile of the 5‐HT2C Receptor Agonist WAY‐163909; Therapeutic Potential in Multiple Indications
2006
Serotonin-Induced Increases in Adult Cell Proliferation and Neurogenesis are Mediated Through Different and Common 5-HT Receptor Subtypes in the Dentate Gyrus and the Subventricular Zone
2003
Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice
2006
Localization of 5-HT6 receptors at the plasma membrane of neuronal cilia in the rat brain
2000
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
2010 Standout
Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT 2C receptors in Wistar rats
2003
Pyrrolo[3,2,1- ij ]quinoline derivatives, a 5-HT 2c receptor agonist with selectivity over the 5-HT 2a receptor: potential therapeutic applications for epilepsy and obesity
2000
ChEMBL: a large-scale bioactivity database for drug discovery
2011 Standout
Selection of boron reagents for Suzuki–Miyaura coupling
2013 Standout
Bidirectional communication between sleep and circadian rhythms and its implications for depression: Lessons from agomelatine
2009
Kinetic Investigation of the Specificity of Porcine Brain Thyrotropin-releasing Hormone-degrading Ectoenzyme for Thyrotropin-releasing Hormone-like Peptides
2000
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. Part 7: Structure–Activity Studies of Bicyclic 2-Pyridone-Containing Peptidomimetics
2002
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Cyclopropane-Derived Peptidomimetics. Design, Synthesis, Evaluation, and Structure of Novel HIV-1 Protease Inhibitors
1998
Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants
2008
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
New Hepatitis C Therapies: The Toolbox, Strategies, and Challenges
2014
Increased monoamine oxidase b activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography
1994
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin
2015 StandoutNobel
Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus
2006
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
2013
A review of central 5-HT receptors and their function
1999 Standout
Major Depressive Disorder
2008 Standout
Synthesis and antibacterial activity of substituted 1,2,3,4-tetrahydropyrazino [1,2-a] indoles
2005
Catalytic Enantioselective Addition of Dialkylzinc Reagents to N‐Acylpyridinium Salts
2009 StandoutNobel
The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways
2003
Benzodiazepine peptidomimetic inhibitors of farnesyltransferase
1994
1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands
2005
Controlled Microwave Heating in Modern Organic Synthesis
2004 Standout
Effects of systemic and intra-nucleus accumbens 5-HT2C receptor compounds on ventral tegmental area self-stimulation thresholds in rats
2008
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade
2004
The way forward in HCV treatment — finding the right path
2007 StandoutNobel
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Substrate and Inhibitor Specificities for Human Monoamine Oxidase A and B Are Influenced by a Single Amino Acid
2001
3d Transition Metals for C–H Activation
2018 Standout
Fluorine in medicinal chemistry
2007 Standout
Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus
2006
Peptidomimetics—Tailored Enzyme Inhibitors
1994
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Recent advances in the synthesis of piperidones and piperidines
2003
Novel Aza-analogous Ergoline Derived Scaffolds as Potent Serotonin 5-HT6 and Dopamine D2 Receptor Ligands.
2014
Pharmacological Approaches for the Treatment of Obesity
2002
Bis(imino)pyridines: Surprisingly Reactive Ligands and a Gateway to New Families of Catalysts
2007 Standout
2-Substituted Tryptamines: Agents with Selectivity for 5-HT6Serotonin Receptors
2000
Research and Development of an Efficient Process for the Construction of the 2,4,5-Substituted Pyridines of NK-1 Receptor Antagonists
2006
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines
2012 Standout
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
X=Y=ZH Systems as potential 1,3-dipoles. Part 58: Cycloaddition route to chiral conformationally constrained (R)-pro-(S)-pro peptidomimetics
2003
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Artificial β-sheets
1996
Modular Synthesis of Cyclic Peptidomimetics Inspired by γ-Turns
2005
Use of a Modified Leimgruber–Batcho Reaction to Prepare 6‐Chloro‐5‐fluoroindole
2004
Sequential Nucleophilic Substitution on Halogenated Triazines, Pyrimidines, and Purines: A Novel Approach to Cyclic Peptidomimetics
2000
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
The Origin of Chalcogen-Bonding Interactions
2017 Standout
The Cation−π Interaction
1997 Standout
Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics
1997
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Stereoselective Cyclopropanation Reactions
2003 Standout
Spermidine in health and disease
2018 StandoutScience
The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches?
2000
Highly efficient one-pot synthesis of 1-substituted-1,2,3,4-tetrahydropyrazino[1,2-a]indoles
2005
Engineering Biomolecular Self‐Assembly at Solid–Liquid Interfaces
2020 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Review HCV Antiviral Resistance: The Impact of in vitro Studies on the Development of Antiviral Agents Targeting the Viral NS5B Polymerase
2005
Solid-Phase Synthesis and Structural Analysis of Bicyclic β-Turn Mimetics Incorporating Functionality at theitoi+ 3 Positions
1999
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Serotonin Receptors
2008
Preparation of 6-chloro-5-fluoroindole via the use of palladium and copper-mediated heterocyclisations
2002
Efficient Synthesis of Novel NK1 Receptor Antagonists: Selective 1,4-Addition of Grignard Reagents to 6-Chloronicotinic Acid Derivatives
2006
Unusual Amino Acids in Medicinal Chemistry
2016
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Construction of Enantiopure Pyrrolidine Ring System via Asymmetric [3+2]-Cycloaddition of Azomethine Ylides
2006 Standout
Medicinal Chemistry Driven Approaches Toward Novel and Selective Serotonin 5-HT6Receptor Ligands
2004
Metal-free C–H sulfonamidation of pyrroles by visible light photoredox catalysis
2016
Proteases and protease inhibitors in infectious diseases
2017
Biomedical Importance of Indoles
2013 Standout
Catalytic Coupling of Arene C–H Bonds and Alkynes for the Synthesis of Coumarins: Substrate Scope and Application to the Development of Neuroimaging Agents
2012
2-Aminophenyl-1H-pyrazole as a Removable Directing Group for Copper-Mediated C–H Amidation and Sulfonamidation
2016
Nucleophilic Addition to 3-Substituted Pyridinium Salts: Expedient Syntheses of (−)-L-733,061 and (−)-CP-99,994
2004
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Synthesis of conformationally constrained potential inhibitors of mammalian metalloproteinases
1997
The synthesis and coordination chemistry of 2,6-bis(pyrazolyl)pyridines and related ligands — Versatile terpyridine analogues
2005
Isolation of methyl (RS)‐1‐tert‐butoxycarbonyl‐3‐cyanomethyl‐1,2‐dihydro‐2‐oxo‐5H‐pyrrole‐5‐carboxylate, the key‐intermediate in base‐catalyzed formation of racemic products by 1,3‐dipolar cycloadditions to methyl (S)‐1‐tert‐butoxycarbonyl‐3‐[(E)‐cyanomethylidene]‐2‐pyrrolidinone‐5‐carboxylate
2002
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Synthesis, Structure and Conformation of Partially‐Modified Retro‐ and Retro‐Inverso ψ[NHCH(CF3)]Gly Peptides
2003
Diastereoselective Synthesis of α,α-Disubstituted γ-Carboxypyroglutamates via Sm(III)−Azomethine Ylide Cycloadditions
1997
5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT6 Receptor Antagonist
1999
Conformational properties of azapeptides
1999
Asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by sequential SN2–SN2′ dialkylation of (R)-N-(benzyl)proline-derived glycine Schiff base Ni(ii ) complex
2014
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Synthesis of Heterocycles from Alkyl 3-(Dimethylamino)propenoates and Related Enaminones
2004 Standout
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Partially Modified Retro-Inverso Peptides: Development, Synthesis, and Conformational Behavior
1998
Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications
2017
Works of Michael Bös being referenced
Characterization of the binding of [3H]Ro 41-1049 to the active site of human monoamine oxidase-A.
1990
Characterization of Ro 04‐6790 and Ro 63‐0563: potent and selective antagonists at human and rat 5‐HT6 receptors
1998
Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors
2013
The 5-Hydroxytryptamine6 Receptor-Selective radioligand [3H]Ro 63–0563 Labels 5-Hydroxytryptamine Receptor Binding Sites in Rat and Porcine Striatum
1998
5HT2C receptor agonists exhibit antidepressant-like properties in the anhedonia model of depression in rats
1996
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives
2003
The Putative 5‐ht6 Receptor: Localization and Function
1998
Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists
2005
5-HT6 receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides
2001
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency
2004
Concepts and progress in the development of peptide mimetics
1993
Involvement of 5‐HT6 receptors in nigro‐striatal function in rodents
1998
Highly Enantioselective Synthesis of 3-Hydroxy-2-phenylpiperidine via the Sharpless AD-Reaction
1999
Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV)
2012
The role of 5ht2c receptors in affective disorders
1998
Novel Agonists of 5HT2C Receptors. Synthesis and Biological Evaluation of Substituted 2-(Indol-1-yl)-1-methylethylamines and 2-(Indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved Therapeutics for Obsessive Compulsive Disorder
1997
Influence of the 5-HT6Receptor on Acetylcholine Release in the Cortex: Pharmacological Characterization of 4-(2-Bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a Potent and Selective 5-HT6Receptor Antagonist
2003
Discovery of a Potent and Selective Noncovalent Linear Inhibitor of the Hepatitis C Virus NS3 Protease (BI 201335)
2010
Synthesis, pharmacology and therapeutic potential of 10-methoxypyrazino[1,2-a]indoles, partial agonists at the 5HT2C receptor
1997
The 5-hydroxytryptamine 6 receptor: localisation and function
1998
5-HT2C Receptor Agonists: Pharmacological Characteristics and Therapeutic Potential
1998