Citation Impact
Citing Papers
Dynamic profiling of the protein life cycle in response to pathogens
2015 Science
Dysfunctional Transforming Growth Factor-β Receptor II Accelerates Prostate Tumorigenesis in the TRAMP Mouse Model
2009
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
edgeR : a Bioconductor package for differential expression analysis of digital gene expression data
2009 Standout
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Next-generation analysis of gene expression regulation – comparing the roles of synthesis and degradation
2015
Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes
2015
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
PI3K signaling in cancer: beyond AKT
2017
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
Ribosome profiling: new views of translation, from single codons to genome scale
2014
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
2005 StandoutNature
Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
2012 Standout
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms
2008 StandoutNobel
Smad transcription factors
2005 Standout
Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans
2014
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
2013
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
2020 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Advances in the treatment of advanced oestrogen-receptor-positive breast cancer
2016
Haematopoietic stem cells require a highly regulated protein synthesis rate
2014 Nature
Quantitative profiling of initiating ribosomes in vivo
2014
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
Scleroderma
2009 Standout
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
2017 StandoutNobel
Regulation of innate immune cell function by mTOR
2015
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
WebLogo: A Sequence Logo Generator: Figure 1
2004 Standout
Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma
2006
Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor
2016 Nature
Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
2004
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error
2014
The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments
2012
TGFβ in Cancer
2008 Standout
T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine
2011 StandoutNobel
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Regulation of type I interferon responses
2013 Standout
Targeting the translation machinery in cancer
2015
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
The PI3K Pathway in Human Disease
2017 Standout
Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer
2004
Prostate cancer invasion and metastasis: insights from mining genomic data
2013
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
2018 StandoutScience
A growing role for mTOR in promoting anabolic metabolism
2013
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
2016
Genome‐Wide Annotation and Quantitation of Translation by Ribosome Profiling
2013
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
2015
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma
2017
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Determination of tag density required for digital transcriptome analysis: Application to an androgen-sensitive prostate cancer model
2008
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression
2015
Overexpression, Amplification, and Androgen Regulation of TPD52 in Prostate Cancer
2004
Metabolic reprogramming and cancer progression
2020 StandoutScience
2012
SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS
2005 Standout
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Evidence that TRPM8 Is an Androgen-Dependent Ca2+ Channel Required for the Survival of Prostate Cancer Cells
2004
Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty
2004
The 4E-BP–eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes
2016
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin Ligases
2014
System wide analyses have underestimated protein abundances and the importance of transcription in mammals
2014
Signalling to eIF4E in cancer
2015
Works of Michael Bonham being referenced
The translational landscape of mTOR signalling steers cancer initiation and metastasis
2012 Nature
The Potential Impact of Reproducibility of Gleason Grading in Men With Early Stage Prostate Cancer Managed by Active Surveillance: A Multi-Institutional Study
2011
The Androgen Receptor Represses Transforming Growth Factor-β Signaling through Interaction with Smad3
2002
The program of androgen-responsive genes in neoplastic prostate epithelium
2002