Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
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Principles for designing proteins with cavities formed by curved β sheets
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Global analysis of protein folding using massively parallel design, synthesis, and testing
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De novo design of transmembrane β barrels
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Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
A Thermodynamic Scale for the .beta.-Sheet Forming Tendencies of the Amino Acids
1994
Polar and nonpolar atomic environments in the protein core: Implications for folding and binding
1994
Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1
1994
Crystallographic Refinement by Knowledge-Based Exploration of Complex Energy Landscapes
2005
A Helix Propensity Scale Based on Experimental Studies of Peptides and Proteins
1998
The Protein Data Bank
2000 Standout
Forces stabilizing proteins
2014
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Studies on Protein Stability With T4 Lysozyme
1995
Halogenated Benzenes Bound within a Non-polar Cavity in T4 Lysozyme Provide Examples of I⋯S and I⋯Se Halogen-bonding
2008
Reversible independent unfolding of the domains of urokinase monitored by proton NMR
1989
Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution
2001 StandoutNatureNobel
Exploring steric constraints on protein mutations using MAGE/PROBE
2000
Design of proteins from smaller fragments—learning from evolution
2014
The dynamic disulphide relay of quiescin sulphydryl oxidase
2012 StandoutNatureNobel
Thoroughly sampling sequence space: Large‐scale protein design of structural ensembles
2002
The road to fully programmable protein catalysis
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Side-Chain Determinants of .beta.-Sheet Stability
1995
Context is a major determinant of β-sheet propensity
1994 Nature
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Protein Design by Binary Patterning of Polar and Nonpolar Amino Acids
1993 Science
Designed Armadillo Repeat Proteins as General Peptide-Binding Scaffolds: Consensus Design and Computational Optimization of the Hydrophobic Core
2008
Optimal description of a protein structure in terms of multiple groups undergoing TLS motion
2006
A Brief History of De Novo Protein Design: Minimal, Rational, and Computational
2021
Contribution of Hydrophobic Interactions to Protein Stability
2011
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
On/off blinking and switching behaviour of single molecules of green fluorescent protein
1997 StandoutNatureNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
PQS: a protein quaternary structure file server
1998
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Access of ligands to cavities within the core of a protein is rapid
1996
Relationship of sidechain hydrophobicity and α‐helical propensity on the stability of the single‐stranded amphipathic α‐helix
1995
Targeting proteinase-activated receptors: therapeutic potential and challenges
2012
Lessons from the lysozyme of phage T4
2010
De novo design of a fluorescence-activating β-barrel
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De novo design of bioactive protein switches
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De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints
2016
Structural Basis of the Enhanced Stability of a Mutant Ribozyme Domain and a Detailed View of RNA–Solvent Interactions
2001 Nobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
High level expression of proinsulin in the yeast, Saccharomyces cerevisiae
1987
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
2005 StandoutNatureNobel
Exploring the repeat protein universe through computational protein design
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Programmable design of orthogonal protein heterodimers
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Controlling protein assembly on inorganic crystals through designed protein interfaces
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Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Structure-based Prediction of bZIP Partnering Specificity
2005
De novo design of the hydrophobic cores of proteins
1995
RosettaHoles: Rapid assessment of protein core packing for structure prediction, refinement, design, and validation
2008 StandoutNobel
The Roles of Ribosomal Proteins in the Structure Assembly, and Evolution of the Large Ribosomal Subunit
2004 StandoutNobel
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Measurement of the β-sheet-forming propensities of amino acids
1994 Nature
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Rational engineering of enzyme stability
2004
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Conformation of one- and two-chain high molecular weight urokinase analyzed by small-angle neutron scattering and vacuum ultraviolet circular dichroism
1991 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
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Volume changes in protein evolution
1994
Functional Proteins from Short Peptides: Dayhoff's Hypothesis Turns 50
2016
Reconstructing NMR Spectra of “Invisible” Excited Protein States Using HSQC and HMQC Experiments
2002
An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis
1989 StandoutScienceNobel
Analysis of Thermodynamic Determinants in Helix Propensities of Nonpolar Amino Acids through a Novel Free Energy Calculation
1996
Computational design of a self-assembling symmetrical β-propeller protein
2014
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Crystal Structure of the Aequorea victoria Green Fluorescent Protein
1996 StandoutScienceNobel
Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2
1996
Surface receptors for urokinase plasminogen activator
1988
A direct comparison of helix propensity in proteins and peptides
1997
Site-specific incorporation of biophysical probes into proteins.
1994
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Structural and genetic analysis of protein folding and stability
1993
One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity.
1988
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Illuminating Single Molecules in Condensed Matter
1999 StandoutScienceNobel
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Cholesterol and the Golgi Apparatus
1993 Science
Structure-Based Thermodynamic Scale of α-Helix Propensities in Amino Acids
1996
Structural Plasticity in a Remodeled Protein-Protein Interface
1997 Science
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells
1998 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Folded proteins occur frequently in libraries of random amino acid sequences.
1994
Helix Propensities Are Identical in Proteins and Peptides
1997
A vocabulary of ancient peptides at the origin of folded proteins
2015
Cloning and Expression of the Gene for Pro-urokinase in Escherichia coli
1985
Works of Michael Blaber being referenced
Experimental support for the evolution of symmetric protein architecture from a simple peptide motif
2010
Accommodation of Amino Acid Insertions in an α-Helix of T4 Lysozyme
1994
Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs)
2006
Alanine Scanning Mutagenesis of the α-Helix 115-123 of Phage T4 Lysozyme: Effects on Structure, Stability and the Binding of Solvent
1995
Alternative Folding Nuclei Definitions Facilitate the Evolution of a Symmetric Protein Fold from a Smaller Peptide Motif
2013
Emergence of symmetric protein architecture from a simple peptide motif: evolutionary models
2012
Proteinase-activated Receptors, Targets for Kallikrein Signaling
2006
Symmetric Protein Architecture in Protein Design: Top-Down Symmetric Deconstruction
2014
Designing proteins from simple motifs: opportunities in Top-Down Symmetric Deconstruction
2012
Determination of α-Helix Propensity within the Context of a Folded Protein
1994
Protein design at the interface of the pre-biotic and biotic worlds
2012
Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala .fwdarw. Ser and Val .fwdarw. Thr substitutions in T4 lysozyme
1993
Expression and Function of the Kallikrein-Related Peptidase 6 in the Human Melanoma Microenvironment
2011
Crystal Structure and Biochemical Characterization of Human Kallikrein 6 Reveals That a Trypsin-like Kallikrein Is Expressed in the Central Nervous System
2002
A Polypeptide “Building Block” for the β-Trefoil Fold Identified by “Top-Down Symmetric Deconstruction”
2011
An atomic resolution structure for human fibroblast growth factor 1
2004
Biological and Thrombolytic Properties of Proenzyme and Active Forms of Human Urokinase – III. Thrombolytic Properties of Natural and Recombinant Urokinase in Rabbits with Experimental Jugular Vein Thrombosis
1984
Purification and Characterization of Recombinant Urokinase from Escherichia coli
1985
Activation of plasminogen by pro-urokinase. I. Mechanism.
1986
Response of a Protein Structure to Cavity-Creating Mutations and Its Relation to the Hydrophobic Effect
1992 Science
Structural Basis of Amino Acid α Helix Propensity
1993 Science
Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein
2013
Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography
1999
Purification and characterization of recombinant single-chain urokinase produced in Escherichia coli
1986
The protease inhibitory properties of the Alzheimer's beta-amyloid precursor protein.
1990