Citation Impact
Citing Papers
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
2007 StandoutScience
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA)
2020
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Degradation of proteins by PROTACs and other strategies
2019
Advances in targeted degradation of endogenous proteins
2019
Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression
2018
Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs
2021
Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
2020
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
2020
Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom
2009
Optical coherence tomography angiography
2017 Standout
Prey for the Proteasome: Targeted Protein Degradation—A Medicinal Chemist's Perspective
2020
Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling
2015 StandoutNobel
Biomolecular Condensates and Cancer
2021
Genomic insights into Wnt signaling in an early diverging metazoan, the ctenophore Mnemiopsis leidyi
2010 Standout
The PROTACtable genome
2021
Nrf2-Keap1 signaling in oxidative and reductive stress
2018 Standout
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
2018
Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
2019
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Genetic interaction networks in cancer cells
2019
TGFβ signalling in context
2012 Standout
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Myelin basic protein‐dependent plasma membrane reorganization in the formation of myelin
2006 StandoutNobel
Cereblon modulators: Low molecular weight inducers of protein degradation
2019
Coenzyme Q10 as a therapy for mitochondrial disease
2014
PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
2020
PROTACs: An Emerging Therapeutic Modality in Precision Medicine
2020
Proteasomal and lysosomal degradation for specific and durable suppression of immunotherapeutic targets
2020
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors
2016
Prevalence of Muscular Dystrophies: A Systematic Literature Review
2014 Standout
Muscular dystrophies
2013
Using the Acropora digitifera genome to understand coral responses to environmental change
2011 StandoutNature
Mitochondrial pharmacology
2012
Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis
2020
Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications
2016
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells
2020
Targeted protein degradation: current and future challenges
2020
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020 StandoutNobel
A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
2017
Phenotypic screening with target identification and validation in the discovery and development of E3 ligase modulators
2021
Targeted protein degradation as a powerful research tool in basic biology and drug target discovery
2020
Targeted protein degradation: expanding the toolbox
2019
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Mitochondrial dysfunction in optic neuropathies
2013
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
2019
Development of targeted protein degradation therapeutics
2019
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals
2008 StandoutNature
Physical Exercise and Cognitive Recovery in Acquired Brain Injury: A Review of the Literature
2009
Kinase inhibitors: the road ahead
2018
Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery
2020
Emerging New Concepts of Degrader Technologies
2020
Therapeutic developments for Duchenne muscular dystrophy
2019
Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression
2021 StandoutNobel
Harnessing the Power of Proteolysis for Targeted Protein Inactivation
2020
Down syndrome
2020 Standout
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation
2021
Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations
2019
Cancer therapies based on targeted protein degradation — lessons learned with lenalidomide
2021
Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16
2019
Degradation from the outside in: Targeting extracellular and membrane proteins for degradation through the endolysosomal pathway
2021 StandoutNobel
Transforming targeted cancer therapy with PROTACs: A forward-looking perspective
2021
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
2019
Targeted Protein Degradation Tools: Overview and Future Perspectives
2020
CRISPR/Cas9 for cancer research and therapy
2018
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals
2011 StandoutScience
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL
2020
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Recent advances in the synthesis of pyrroles by multicomponent reactions
2014 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Unifying Catalysis Framework to Dissect Proteasomal Degradation Paradigms
2021
Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells
2022 StandoutNobel
Multicomponent reactions: advanced tools for sustainable organic synthesis
2014 Standout
Guidelines for Adult Stroke Rehabilitation and Recovery
2016 Standout
Natural product and natural product derived drugs in clinical trials
2014 Standout
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer
2018
Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
2021
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Chemically induced proximity in biology and medicine
2018 Science
The raft-associated protein MAL is required for maintenance of proper axon–glia interactions in the central nervous system
2004
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Works of Michael A. Erb being referenced
ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
2017 Nature
Novel cell-penetrating α-keto-amide calpain inhibitors as potential treatment for muscular dystrophy
2005
NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels
2011
BMP2/4 and BMP5-8 in jellyfish development and transdifferentiation
2006
Omigapil Ameliorates the Pathology of Muscle Dystrophy Caused by Laminin-α2 Deficiency
2009
Idebenone Protects against Retinal Damage and Loss of Vision in a Mouse Model of Leber’s Hereditary Optic Neuropathy
2012
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands
2018
Unraveling the differential expression of the two isoforms of myelin-associated glycoprotein in a mouse expressing GFP-tagged S-MAG specifically regulated and targeted into the different myelin compartments
2006
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation
2017
Features of Idebenone and Related Short-Chain Quinones that Rescue ATP Levels under Conditions of Impaired Mitochondrial Complex I
2012
Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
2008
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
2018
Differential expression of L‐ and S‐MAG upon cAMP stimulated differentiation in oligodendroglial cells
2002
The dTAG system for immediate and target-specific protein degradation
2018
Transcription control by the ENL YEATS domain in acute leukaemia
2017 Nature
Synthesis and Evaluation of Calpain Inhibitors Carrying Muscle Cell Targeting Groups
2006
Apoptosis inhibitors and mini‐agrin have additive benefits in congenital muscular dystrophy mice
2011
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia
2021 StandoutNobel
Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders
2018