Citation Impact
Citing Papers
Subtypes of HPV-Positive Head and Neck Cancers Are Associated with HPV Characteristics, Copy Number Alterations, PIK3CA Mutation, and Pathway Signatures
2016
Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs.
2000 StandoutNobel
The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials
2001 Standout
PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia
2016 StandoutNobel
Tumor Hypoxia in Cancer Therapy
2007
Why do cancers have high aerobic glycolysis?
2004 Standout
Molecular imaging in drug development
2008 Standout
Induction of HIF‐1α expression by intermittent hypoxia: Involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR
2008 StandoutNobel
Targeting hypoxia in cancer therapy
2011 Standout
The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials
2001 Standout
Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers
2003
The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy
2015 Standout
Intermittent hypoxia changes HIF-1α phosphorylation pattern in endothelial cells: Unravelling of a new PKA-dependent regulation of HIF-1α
2007
Altered fractionation and combined radio-chemotherapy approaches
2003
Tumor microcirculation and diffusion predict therapy outcome for primary rectal carcinoma
2003
ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)
2009 Standout
Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis
2006 Standout
Continuous, hyperfractionated, accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: mature data from the randomised multicentre trial
1999
Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer
2000
A randomised multicentre trial of CHART versus conventional radiotherapy in head and neck cancer
1997
Drug penetration in solid tumours
2006 Standout
Lung Cancer
2008 Standout
Head and neck cancer
2008 Standout
Tumor-line specific pO2 fluctuations in human melanoma xenografts
2004
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Acute versus chronic hypoxia in tumors
2012
Temporal changes in pO2 of R3230Ac tumors in fischer-344 rats
1998
Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and Recommendations
2009 Standout
Hyperfractionated Irradiation with or without Concurrent Chemotherapy for Locally Advanced Head and Neck Cancer
1998 Standout
Intermittent Blood Flow in Solid Tumours – an under-appreciated Source of ‘drug Resistance’
2001
Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small-cell lung cancer: a randomised multicentre trial
1997
Molecular mechanisms of cisplatin resistance
2011 Standout
Exploiting tumour hypoxia in cancer treatment
2004 Standout
Targeting Bcl-2 and Bcl-X with nonpeptidic small-molecule antagonists
2003
Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
2006 Standout
Changes in tumor oxygenation/perfusion induced by the no donor, isosorbide dinitrate, in comparison with carbogen: monitoring by EPR and MRI
2000
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Towards evidence based radiation oncology: improving the design, analysis, and reporting of clinical outcome studies in radiotherapy
1998
Clinical use of intensity-modulated radiotherapy: part II
2004
Pre-trial quality assurance processes for an intensity-modulated radiation therapy (IMRT) trial: PARSPORT, a UK multicentre Phase III trial comparing conventional radiotherapy and parotid-sparing IMRT for locally advanced head and neck cancer
2009
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON
2003
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
2010 Standout
The Hypoxic Tumour Microenvironment, Patient Selection and Hypoxia-modifying Treatments
2007
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
2005 Standout
Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review
2003 Standout
The macrophage – a novel system to deliver gene therapy to pathological hypoxia
2000 StandoutNobel
Dosimetry audit for a multi-centre IMRT head and neck trial
2009
Targeting tumors with hypoxia-activated cytotoxins
2007
The molecular landscape of head and neck cancer
2018 Standout
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
2010 Standout
Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial
2011 Standout
Regional chemotherapy for unresectable primary liver cancer: results of a phase II clinical trial and assessment of DCE-MRI as a biomarker of survival
2009
Clinical use of intensity-modulated radiotherapy: part I
2004
Exploring the full spectrum of macrophage activation
2008 Standout
Hypoxia and oxidative stress in breast cancer Hypoxia and tumourigenesis
2001
Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study
2020 Standout
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
Patients with head and neck cancer cured by radiation therapy: A survey of the dry mouth syndrome in long‐term survivors
2002
Can nanotechnology potentiate photodynamic therapy?
2012
Physiological effects of indomethacin and celecobix: anS-transform laser Doppler flowmetry signal analysis
2005 StandoutNobel
Head and Neck Cancer
2001 Standout
A phase I/II trial of twice daily irradiation and concurrent chemotherapy for locally advanced squamous cell carcinoma of the head and neck
1994
Drug Resistance and the Solid Tumor Microenvironment
2007 Standout
Molecular Imaging of Antiangiogenic Agents
2005
Principles and practice of the laser-Doppler perfusion technique
1999
Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway
2017 StandoutNobel
Protein kinase A–dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1
2016 StandoutNobel
Microenvironment and Radiation Therapy
2012
Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density.
2001 StandoutNobel
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Nanoparticles in Photodynamic Therapy
2015 Standout
The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials
2001 Standout
Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats
1999
Improvement of Tumor Response by Manipulation of Tumor Oxygenation During Photodynamic Therapy¶
2002
Spontaneous Transformation of Cultured Mouse Bone Marrow–Derived Stromal Cells
2006 StandoutNobel
New photosensitizers for photodynamic therapy
2016 Standout
Hypoxia down-regulates MCP-1 expression: implications for macrophage distribution in tumors
1998
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration
2001 Standout
Direct Demonstration of Instabilities in Oxygen Concentrations within the Extravascular Compartment of an Experimental Tumor
2006
The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.
1999
Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology
2007 Standout
Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma.
1996
Mcl-1, Vascular Endothelial Growth Factor-R2, and 14-3-3σ Expression Might Predict Primary Response against Radiotherapy and Chemotherapy in Patients with Locally Advanced Squamous Cell Carcinomas of the Head and Neck
2005
American Society of Clinical Oncology Treatment of Unresectable Non–Small-Cell Lung Cancer Guideline: Update 2003
2003 Standout
Review of methods used to study oxygen transport at the microcirculatory level
2000
Works of M.I. Saunders being referenced
The dental problems of patients with head and neck cancer treated with CHART
1996
bcl-2 expression in head and neck cancer: an enigmatic prognostic marker
2001
Dynamic contrast enhanced magnetic resonance scanning as a predictor of response to accelerated radiotherapy for advanced head and neck cancer.
1999
Where exactly does failure occur after radiation in head and neck cancer?
1995
Quality assurance in the CHART clinical trial
1995
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma
1999
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma
1999
Continuous, hyperfractionated, accelerated radiotherapy (CHART)
1992
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide.
1999
Human tumor blood flow is enhanced by nicotinamide and carbogen breathing.
1997
Microregional blood flow in murine and human tumours assessed using laser Doppler microprobes.
1996