Citation Impact
Citing Papers
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
2005 StandoutNobel
Induction of Tumors in Mice by Genomic Hypomethylation
2003 Science
Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2
2003 StandoutScience
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
A t(1;19)(q10;p10) Mediates the Combined Deletions of 1p and 19q and Predicts a Better Prognosis of Patients with Oligodendroglioma
2006
Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi
2002 StandoutScience
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
2002 Standout
Dnmt3L and the Establishment of Maternal Genomic Imprints
2001 Science
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Syndromes of disordered chromatin remodeling
2003
Molecular studies of major depressive disorder: the epigenetic perspective
2007
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Recombinant Human DNA (Cytosine-5) Methyltransferase
1999 Nobel
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
Phenotypic plasticity and the epigenetics of human disease
2007 Nature
A histone H3 methyltransferase controls DNA methylation in Neurospora crassa
2001 Nature
DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system
2004
Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery
2004
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Molecular genetics of Rett syndrome and clinical spectrum of MECP2 mutations
2001
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
2005
DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes
2001
The history of cancer epigenetics
2004 Standout
The contribution of <i>cis</i>-elements to disease-associated repeat instability: clinical and experimental evidence
2003
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
DNA methylation patterns and epigenetic memory
2002 Standout
The epigenetic regulation of mammalian telomeres
2007
Large-scale structure of genomic methylation patterns
2005
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells
2006
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
2000
DNA hypomethylation and unusual chromosome instability in cell lines fromICF syndrome patients
2000
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 StandoutNobel
Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine
2001
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases
2001
CpG methylation is maintained in human cancer cells lacking DNMT1
2000 Nature
Hallmarks of aging: An expanding universe
2023 Standout
Gilbert’s conjecture: the search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases 1 1Edited by J. Karn
2000
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma
2003
The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease
2003
Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development
2008
DNA methylation and chromatin – unraveling the tangled web
2002
DNA methylation and gene silencing in cancer: which is the guilty party?
2002
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
2008 StandoutNature
DNA methylation in health and disease
2000
Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpA sites
2001
The Epigenomics of Cancer
2007 Standout
Transposon Silencing and Imprint Establishment in Mammalian Germ Cells
2004
DNA methylation: roles in mammalian development
2013 Standout
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
2001
DNMT3B mutations and DNA methylation defect define two types of ICF syndrome
2004
Limb malformations and the human HOX genes
2002
MeCP2 and MBD2 expression during normal and pathological growth of the human mammary gland
2002
Molecular Enzymology of the Catalytic Domains of the Dnmt3a and Dnmt3b DNA Methyltransferases
2002
Epigenetics in Cancer
2008 Standout
Dnmt3a and Dnmt3b Are Transcriptional Repressors That Exhibit Unique Localization Properties to Heterochromatin
2001
The complex language of chromatin regulation during transcription
2007 StandoutNature
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
2000
Cytosine Methylation and DNA Repair
2006
Methylation matters
2001
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
2002 StandoutNatureNobel
Maintenance of self‐renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
2006
Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos
2001
Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin
2003
Genomic Imprinting Disrupted by a Maternal Effect Mutation in the Dnmt1 Gene
2001
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
2011
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
2008 Nature
Dynamics of DNA methylation pattern
2000
Malignant Gliomas in Adults
2008 Standout
Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy
2003
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
X-chromosome inactivation: counting, choice and initiation
2001
Epigenetic gene regulation: Linking early developmental environment to adult disease
2006
Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos
2001
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future
2002
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
2007
Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells
2002
Genome-Wide Copy Number Variation in Epilepsy: Novel Susceptibility Loci in Idiopathic Generalized and Focal Epilepsies
2010
The Polycomb group protein EZH2 directly controls DNA methylation
2005 StandoutNature
Insights into social insects from the genome of the honeybee Apis mellifera
2006 StandoutNature
Expression Pattern of the Rett Syndrome Gene MeCP2 in Primate Prefrontal Cortex
2001
Cytokinesis-block micronucleus cytome assay
2007 Standout
RNA interference
2002 StandoutNature
Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases
2001
Above and Within the Genome: Epigenetics Past and Present
2001
Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant
2000
Lsh, a member of the SNF2 family, is required for genome-wide methylation
2001
Dynamics of Dnmt1 Methyltransferase Expression and Intracellular Localization during Oogenesis and Preimplantation Development
2002
Rethinking how DNA methylation patterns are maintained
2009
ICF Syndrome Mutations Cause a Broad Spectrum of Biochemical Defects in DNMT3B-Mediated De Novo DNA Methylation
2011
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
2010
The Hallmarks of Aging
2013 Standout
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
2001
Breakpoints around the HOXD cluster result in various limb malformations
2005
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
2001
The molecular neurobiology of depression
2008 StandoutNature
The fundamental role of epigenetic events in cancer
2002 Standout
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
Methylation dynamics of repetitive DNA elements in the mouse germ cell lineage
2003
DNA of Drosophila melanogaster contains 5-methylcytosine
2000
DNA methylation and human disease
2005 Standout
Identification and Characterization of the DNA Binding Domain of CpG-binding Protein
2001
The DNA methyltransferases of mammals
2000 Standout
Disruption of the CNTNAP2 gene in a t(7;15) translocation family without symptoms of Gilles de la Tourette syndrome
2007
MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
2005 Standout
Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2
2000
Synergism of Xist Rna, DNA Methylation, and Histone Hypoacetylation in Maintaining X Chromosome Inactivation
2001
Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
2010
DNA Methylation and Epigenetic Inheritance in Plants and Filamentous Fungi
2001 Science
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Epigenetic Reprogramming in Mammalian Development
2001 StandoutScience
Reduced Rates of Gene Loss, Gene Silencing, and Gene Mutation in Dnmt1-Deficient Embryonic Stem Cells
2001
The PWWP Domain of Dnmt3a and Dnmt3b Is Required for Directing DNA Methylation to the Major Satellite Repeats at Pericentric Heterochromatin
2004
Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
2002
GENETIC EFFECTS OF METHYLATION DIETS
2002
Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
2001
DNA methylation in systemic lupus erythematosus
2003
The Role of DNA Methylation in Mammalian Epigenetics
2001 StandoutScience
Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes
2002
Cancer Genome Landscapes
2013 StandoutScience
Cell division is required for de novo methylation of CpG islands in bladder cancer cells.
2002
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Conserved plant genes with similarity to mammalian de novo DNA methyltransferases
2000
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
2006 StandoutNobel
Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues
2010
Works of Merete Bugge being referenced
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
1999 Nature
Mutations in autism susceptibility candidate 2 (AUTS2) in patients with mental retardation
2007
Systematic re-examination of carriers of balanced reciprocal translocations: a strategy to search for candidate regions for common and complex diseases
2006
HOXD13 polyalanine tract expansion in classical synpolydactyly type Vordingborg
2002