Standout Papers
Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
2014
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
2023 Standout
Sirtuins as regulators of metabolism and healthspan
2012 Standout
AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan
2011 Standout
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
SIRT1: Regulation of longevity via autophagy
2009
HIF-1: upstream and downstream of cancer metabolism
2009 StandoutNobel
Brown and beige fat: development, function and therapeutic potential
2013 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice
2010
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Autophagy and the Integrated Stress Response
2010 Standout
Sirtuin 1 in lipid metabolism and obesity
2011
Regulation of SIRT1 in cellular functions: Role of polyphenols
2010
Epigenetics and the environment: emerging patterns and implications
2012 Standout
The genetics of ageing
2010 StandoutNature
Calorie restriction and the exercise of chromatin
2009
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
2016
Neural mechanisms of ageing and cognitive decline
2010 Nature
Hallmarks of aging: An expanding universe
2023 Standout
Calorie restriction effects on silencing and recombination at the yeast rDNA
2009
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Energetics, epigenetics, mitochondrial genetics
2009
SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons
2008
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
2015
Inflammaging: a new immune–metabolic viewpoint for age-related diseases
2018 Standout
Sirtuins, Aging, and Metabolism
2011
The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance
2009
Roles of SIRT1 in the Acute and Restorative Phases following Induction of Inflammation
2010
Cellular and molecular mechanisms of renal fibrosis
2011 Standout
Mitophagy in neurodegeneration and aging
2017
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Association of SIRT1 gene variation with visceral obesity
2008
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
2016 Standout
Metabolic Reprogramming of Human Cells in Response to Oxidative Stress: Implications in the Pathophysiology and Therapy of Mitochondrial Diseases
2014
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Electron Transport Chain-dependent and -independent Mechanisms of Mitochondrial H2O2 Emission during Long-chain Fatty Acid Oxidation
2009
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
2012 Standout
SIRT1: recent lessons from mouse models
2010
Recent progress in the biology and physiology of sirtuins
2009 Nature
Sirtuin 1 (SIRT1) Deacetylase Activity Is Not Required for Mitochondrial Biogenesis or Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation following Endurance Exercise
2011
The controversial links among calorie restriction, SIRT1, and resveratrol
2011
Autophagy and Aging
2011 Standout
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
How does SIRT1 affect metabolism, senescence and cancer?
2008
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
2010
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
2009
Caloric restriction mimetics: towards a molecular definition
2014
<p>Reactive Oxygen Species: Drivers of Physiological and Pathological Processes</p>
2020 Standout
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
Antimicrobial strategies centered around reactive oxygen species – bactericidal antibiotics, photodynamic therapy, and beyond
2013 Standout
The Hallmarks of Aging
2013 Standout
Energy Metabolism in the Liver
2014 Standout
SIRT1 Negatively Regulates the Mammalian Target of Rapamycin
2010
Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
2011
Anti-aging pharmacology: Promises and pitfalls
2016
Mitochondria and cancer
2012 Standout
The Aging Stress Response
2010
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Frailty in elderly people
2013 Standout
SIRT1, Is It a Tumor Promoter or Tumor Suppressor?
2009
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
2010
Sirtuin signaling in cellular senescence and aging
2019
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
NF-κB in Aging and Disease.
2011 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
AMPK and SIRT1: a long-standing partnership?
2010
The sirtuins, oxidative stress and aging: an emerging link
2013
Properties of Resveratrol:In VitroandIn VivoStudies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans
2015 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Mammalian Sirtuins: Biological Insights and Disease Relevance
2010 Standout
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
Spermidine in health and disease
2018 StandoutScience
PPAR.BETA./.DELTA. regulates the human SIRT1 gene transcription via Sp1
2010
The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction
2012
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues
2010 StandoutNobel
Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)
2014
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
2010 Standout
Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/− Mice: A Role of Lipid Mobilization and Inflammation
2010
Regulation of mitochondrial biogenesis
2010
SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats
2009
Sirtuins — novel therapeutic targets to treat age-associated diseases
2008
The Adipocyte-Expressed Forkhead Transcription Factor Foxc2 Regulates Metabolism Through Altered Mitochondrial Function
2011
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives
2015 Standout
Works of Meredith Evans being referenced
SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice
2008