Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A
2007 Science
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Simultaneous prediction of protein folding and docking at high resolution
2009 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Emergence of symmetry in homooligomeric biological assemblies
2008 StandoutNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Transthyretin: a multifaceted protein
2014
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy
2013
Structural diversity of heparan sulfate binding domains in chemokines
2002
Hepatic metabolism of retinoids and disease associations
2011
Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors
2013
Rational design of potent human transthyretin amyloid disease inhibitors.
2000
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma
2009
Synthetic Molecular Motors and Mechanical Machines
2006 Standout
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Vitamin A Transport and the Transmembrane Pore in the Cell-Surface Receptor for Plasma Retinol Binding Protein
2013
Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome
2006
Natural‐Product Sugar Biosynthesis and Enzymatic Glycodiversification
2008
Additivity-based prediction of equilibrium constants for some protein–protein associations
2003
Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses
2010
A comparative analysis of 23 structures of the amyloidogenic protein transthyretin
2000
Surface-Induced Dissociation of Homotetramers with D2 Symmetry Yields their Assembly Pathways and Characterizes the Effect of Ligand Binding
2015
Electrically driven directional motion of a four-wheeled molecule on a metal surface
2011 StandoutNatureNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Quantification of Transthyretin Kinetic Stability in Human Plasma Using Subunit Exchange
2014
Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer
1999
RosettaLigand Docking with Full Ligand and Receptor Flexibility
2008 StandoutNobel
Structural biology of hepatitis C virus
2004
The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug
2012
The Drosophila takeout Gene Is a Novel Molecular Link between Circadian Rhythms and Feeding Behavior
2000 StandoutNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
The active conformation of human glucokinase is not altered by allosteric activators
2011
Monophyly of class I aminoacyl tRNA synthetase, USPA, ETFP, photolyase, and PP‐ATPase nucleotide‐binding domains: implications for protein evolution in the RNA world
2002
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
The Evolution of Gene Expression, Structure and Function of Transthyretin
1997
Role of conserved residues in structure and stability: Tryptophans of human serum retinol‐binding protein, a model for the lipocalin superfamily
2001
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase
2006 StandoutNobel
A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity
2009
Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein
1999
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
Structural Symmetry and Protein Function
2000
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Bioorganometallic Chemistry of Ferrocene
2004 Standout
Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice
2001 StandoutNobel
Potent and Selective Structure-Based Dibenzofuran Inhibitors of Transthyretin Amyloidogenesis: Kinetic Stabilization of the Native State
2005
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Cooperative light-induced molecular movements of highly ordered azobenzene self-assembled monolayers
2007 StandoutNobel
Hydration of Beryllium, Magnesium, Calcium, and Zinc Ions Using Density Functional Theory
1998
The lipocalin protein family: structure and function
1996 Standout
The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis
2001
Isolation by crystallization of translational isomers of a bistable donor-acceptor [2]catenane
2010 StandoutNobel
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
2012
Ligand-Binding Proteins: Their Potential for Application in Systems for Controlled Delivery and Uptake of Ligands
2000
Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis
2003
Synthesis and Characterization of Potent Bivalent Amyloidosis Inhibitors That Bind Prior to Transthyretin Tetramerization
2003
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Optimizing rotary processes in synthetic molecular motors
2009 StandoutNobel
Structure-Based Design of N-Phenyl Phenoxazine Transthyretin Amyloid Fibril Inhibitors
2000
Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis
2005
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Crystal structure and reactivity of [Ru{C6H4(NH)2-1,2}-(PPh3)3] with π-acid ligands
1993
Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging–what we know and what we need to learn
2013
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
2009
Toward Optimization of the Linker Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies
2008
Inhibiting transthyretin conformational changes that lead to amyloid fibril formation
1998
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Toward Optimization of the Second Aryl Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies
2009
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Potent Kinetic Stabilizers That Prevent Transthyretin-Mediated Cardiomyocyte Proteotoxicity
2011
Modeling the Structural Basis of Human CCR5 Chemokine Receptor Function: From Homology Model Building and Molecular Dynamics Validation to Agonist and Antagonist Docking
2006
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Imaging the glycome
2008 StandoutNobel
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Biochemical and Structural Evaluation of Highly Selective 2-Arylbenzoxazole-Based Transthyretin Amyloidogenesis Inhibitors
2007
Quantum Mechanical Continuum Solvation Models
2005 Standout
Fucose: biosynthesis and biological function in mammals
2003
Toward understanding phosphoseryl-tRNA Cys formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase
2007 StandoutNobel
An amino acid code to define a protein's tertiary packing surface
2015
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
The Metal−Ligand Bifunctional Catalysis: A Theoretical Study on the Ruthenium(II)-Catalyzed Hydrogen Transfer between Alcohols and Carbonyl Compounds
2000 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of Menico Rizzi being referenced
Inhibition of the Hepatitis C Virus NS3/4A Protease
2000
Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme–membrane association control
1999
Enhancement of the HIV-1 inhibitory activity of RANTES by modification of the N-terminal region: dissociation from CCR5 activation
2000
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily
1998
Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition
1995
Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES.
2001
Crystal structure of the bovine α-chymotrypsin:kunitz inhibitor complex. An example of multiple protein:protein recognition sites
1997
Cyanide Binding to Lucina pectinata Hemoglobin I and to Sperm Whale Myoglobin: An X-Ray Crystallographic Study
1999
New structures of allosteric proteins revealing remarkable conformational changes
1996
Crystallization of the Macromolecular Complex Transthyretin-Retinol-binding Protein
1994
Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein
1995 Science
Metal complexes of 1,2-diaminobenzene derivatives. Determination of the oxidation state of the ligands through crystallographic data
1991
Crystal structure of D-amino acid oxidase: a case of active site mirror-image convergent evolution with flavocytochrome b2.
1996
Target Flexibility: An Emerging Consideration in Drug Discovery and Design
2008
Comparison of the co-ordinative behaviour of calcium(II) and magnesium(II) from crystallographic data
1993
Crystal structure of NH3-dependent NAD+ synthetase from Bacillus subtilis.
1996
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD+ biosynthesis
2000