Citation Impact
Citing Papers
Profiling the Specificity of Neutralizing Antibodies in a Large Panel of Plasmas from Patients Chronically Infected with Human Immunodeficiency Virus Type 1 Subtypes B and C
2008
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Vaccine-delivered HIV envelope inhibits CD4+ T-cell activation, a mechanism for poor HIV vaccine responses
2006 StandoutNobel
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection
2008
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination
2014
Human Immunodeficiency Virus Type 1 gp41 Antibodies That Mask Membrane Proximal Region Epitopes: Antibody Binding Kinetics, Induction, and Potential for Regulation in Acute Infection
2007
Memory CD8 + T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection
2003 StandoutNobel
Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition
2003 Science
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
2013 Science
A Potent Cross-Clade Neutralizing Human Monoclonal Antibody against a Novel Epitope on gp41 of Human Immunodeficiency Virus Type 1
2001
HIV-Specific IgG in Cervicovaginal Secretions of Exposed HIV-Uninfected Female Sexual Partners of HIV-Infected Men
2001
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
2017 StandoutNobel
Using Phage Display to Select Antibodies Recognizing Post-translational Modifications Independently of Sequence Context
2006 StandoutNobel
Vector-Mediated Antibody Gene Transfer for Infectious Diseases
2015
The biochemistry of activation-induced deaminase and its physiological functions
2012
Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
2005
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity
2010 StandoutNobel
Distribution and three-dimensional structure of AIDS virus envelope spikes
2006 Nature
Cervicovaginal Secretory Antibodies to Human Immunodeficiency Virus Type 1 (HIV‐1) that Block Viral Transcytosis through Tight Epithelial Barriers in Highly Exposed HIV‐1–Seronegative African Women
2001
HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane
2008
Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate
2005
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Peptide Epitope Identification by Affinity Selection on Bacteriophage MS2 Virus-Like Particles
2011
Correlates of Nontransmission in US Women at High Risk of Human Immunodeficiency Virus Type 1 Infection through Sexual Exposure
2002
Molecular programming of B cell memory
2011
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
Structural Basis of Enhanced Binding of Extended and Helically Constrained Peptide Epitopes of the Broadly Neutralizing HIV-1 Antibody 4E10
2006
Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions
2010
B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
2012
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
2016
Structure of an unliganded simian immunodeficiency virus gp120 core
2005 Nature
Hepatitis C Virus Continuously Escapes From Neutralizing Antibody and T-Cell Responses During Chronic Infection In Vivo
2006 StandoutNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Antibody-based protection against HIV infection by vectored immunoprophylaxis
2011 NatureNobel
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Antibodies against viruses: passive and active immunization
2008
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
HIV-Specific Antibodies But Not T-Cell Responses Are Associated With Protection in Seronegative Partners of HIV-1-Infected Individuals in Cambodia
2006 StandoutNobel
Antibody neutralization and escape by HIV-1
2003 StandoutNature
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5
2010
HIV–host interactome revealed directly from infected cells
2016
Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies
2016
Broad Human Immunodeficiency Virus (HIV)–Specific T Cell Responses to Conserved HIV Proteins in HIV‐Seronegative Women Highly Exposed to a Single HIV‐Infected Partner
2003
Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site
2008
Membrane Fusion
2003 StandoutNobel
Neutralizing antiviral antibody responses
2001
Super-resolution biomolecular crystallography with low-resolution data
2010 StandoutNatureNobel
Activation-induced cytidine deaminase structure and functions: A species comparative view
2011
Tyrosine Sulfation of Human Antibodies Contributes to Recognition of the CCR5 Binding Region of HIV-1 gp120
2003
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site
2017 StandoutNobel
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Challenges for structure-based HIV vaccine design
2009
A Blueprint for HIV Vaccine Discovery
2012
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants
2006
Functional HIV-1 specific IgA antibodies in HIV-1 exposed, persistently IgG seronegative female sex workers
2001
The quest for an AIDS vaccine: is the CD8+ T-cell approach feasible?
2002
Cross-Clade HIV-1–Specific Neutralizing IgA in Mucosal and Systemic Compartments of HIV-1–Exposed, Persistently Seronegative Subjects
2002
Immunopathogenesis and immunotherapy in AIDS virus infections
2003
Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10
2013
Mucosal and systemic HIV-1-specific immunity in HIV-1-exposed but uninfected heterosexual men
2003
Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope
2010 StandoutNobel
Mutations That Destabilize the gp41 Core Are Determinants for Stabilizing the Simian Immunodeficiency Virus-CPmac Envelope Glycoprotein Complex
2002
Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?
2009
Determinants of sequence-specificity within human AID and APOBEC3G
2010
Structural definition of a conserved neutralization epitope on HIV-1 gp120
2007 Nature
Selective degradation of splicing factor CAPERα by anticancer sulfonamides
2017
Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs
2013
Structural Analysis of the Epitope of the Anti-HIV Antibody 2F5 Sheds Light into Its Mechanism of Neutralization and HIV Fusion
2003
Role of lipid structure in the humoral immune response in mice to covalent lipid–peptides from the membrane proximal region of HIV-1 gp41
2009
Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state
2006
Catalytic Pocket Inaccessibility of Activation-Induced Cytidine Deaminase Is a Safeguard against Excessive Mutagenic Activity
2015
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Structure and Mechanistic Analysis of the Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5 in Complex with Its gp41 Epitope
2004
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem
2017
Structure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation,
2009
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine
2006 StandoutNobel
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Resistance to HIV-1 infection: lessons learned from studies of highly exposed persistently seronegative (HEPS) individuals.
2003
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions
2010
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Anti-HIV B Cell Lines as Candidate Vaccine Biosensors
2012
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein
2005
Induction of Mucosal and Systemic Neutralizing Antibodies against Human Immunodeficiency Virus Type 1 (HIV-1) by Oral Immunization with Bovine Papillomavirus-HIV-1 gp41 Chimeric Virus-Like Particles
2004
Structural Basis for Potent Cross-Neutralizing Human Monoclonal Antibody Protection against Lethal Human and Zoonotic Severe Acute Respiratory Syndrome Coronavirus Challenge
2008
Unmutated Immunoglobulin M Can Protect Mice from Death by Influenza Virus Infection
2003 StandoutNobel
The Role of Antibody Polyspecificity and Lipid Reactivity in Binding of Broadly Neutralizing Anti-HIV-1 Envelope Human Monoclonal Antibodies 2F5 and 4E10 to Glycoprotein 41 Membrane Proximal Envelope Epitopes
2007
Ablation of the Complementarity-Determining Region H3 Apex of the Anti-HIV-1 Broadly Neutralizing Antibody 2F5 Abrogates Neutralizing Capacity without Affecting Core Epitope Binding
2010
Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120
2002
Antibodies in HIV-1 Vaccine Development and Therapy
2013 Science
Developing an AIDS Vaccine: Need, Uncertainty, Hope
2004 Science
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Viral persistencein vivothrough selection of neutralizing antibody-escape variants
2000
Antibody Responses Elicited in Macaques Immunized with Human Immunodeficiency Virus Type 1 (HIV-1) SF162-Derived gp140 Envelope Immunogens: Comparison with Those Elicited during Homologous Simian/Human Immunodeficiency Virus SHIVSF162P4and Heterologous HIV-1 Infection
2006
Antigenic conservation and immunogenicity of the HIV coreceptor binding site
2005
Characterization of Infectious Retroviral Pseudotype Particles Bearing Hepatitis C Virus Glycoproteins
2004 StandoutNobel
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection
2005
Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody
2010
Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals
2008
Modeling the Structural Basis of Human CCR5 Chemokine Receptor Function: From Homology Model Building and Molecular Dynamics Validation to Agonist and Antagonist Docking
2006
Predictive value of anti-cell and anti-human immunodeficiency virus (HIV) humoral responses in HIV-1-exposed seronegative cohorts of European and Asian origin
2005
Broad Neutralization of Human Immunodeficiency Virus Type 1 (HIV-1) Elicited from Human Rhinoviruses That Display the HIV-1 gp41 ELDKWA Epitope
2009
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface
2009
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
2011 StandoutNobel
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
HIV VACCINES
2005
Amino-Terminal Phosphorylation of Activation-Induced Cytidine Deaminase Suppresses c-myc/IgH Translocation
2010
Structural insights into key sites of vulnerability on HIV ‐1 Env and influenza HA
2012
The relationship between hypothesis and experiment in unveiling the mechanisms of antibody gene diversification
2011
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies
2008
Antigenic and Immunogenic Study of Membrane-Proximal External Region-Grafted gp120 Antigens by a DNA Prime-Protein Boost Immunization Strategy
2007
Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes.
2008 Nobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region
2009
Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10
2009
Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity
2009
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
2006 StandoutNobel
Structure-Function Analysis of the Epitope for 4E10, a Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody
2006
Progress toward active or passive HIV-1 vaccination
2016
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design
2001 Science
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
2009
The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120
2002
Identification of an Antigenic Determinant on the S2 Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Capable of Inducing Neutralizing Antibodies
2004
Works of Meng Wang being referenced
Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia
2000
Neutralizing Antibodies Have Limited Effects on the Control of Established HIV-1 Infection In Vivo
1999
AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity
2009
CAPER Is Vital for Energy and Redox Homeostasis by Integrating Glucose-Induced Mitochondrial Functions via ERR-α-Gabpa and Stress-Induced Adaptive Responses via NF-κB-cMYC
2015
Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies
2004
Antibody Neutralization-Resistant Primary Isolates of Human Immunodeficiency Virus Type 1
1998
A Novel Human Antibody against Human Immunodeficiency Virus Type 1 gp120 Is V1, V2, and V3 Loop Dependent and Helps Delimit the Epitope of the Broadly Neutralizing Antibody Immunoglobulin G1 b12
2003
Heterogeneity of Envelope Molecules Expressed on Primary Human Immunodeficiency Virus Type 1 Particles as Probed by the Binding of Neutralizing and Nonneutralizing Antibodies
2002
The Human Immunodeficiency Virus Type 1 Envelope Spike of Primary Viruses Can Suppress Antibody Access to Variable Regions
2008
Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID
2010
Molecular Features of the Broadly Neutralizing Immunoglobulin G1 b12 Required for Recognition of Human Immunodeficiency Virus Type 1 gp120
2003
Anti-Human Immunodeficiency Virus Type 1 (HIV-1) Antibodies 2F5 and 4E10 Require Surprisingly Few Crucial Residues in the Membrane-Proximal External Region of Glycoprotein gp41 To Neutralize HIV-1
2004
An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10
2007
The Long Third Complementarity-Determining Region of the Heavy Chain Is Important in the Activity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5
2004
Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41
2001
Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies
2001
The CCR5 receptor acts as an alloantigen in CCR5Δ32 homozygous individuals: Identification of chemokineand HIV-1-blocking human antibodies
1998