Citation Impact
Citing Papers
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Planetary boundaries: Guiding human development on a changing planet
2015 StandoutScience
Reconstituting Organ-Level Lung Functions on a Chip
2010 StandoutScience
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
A Micropatterned Hepatocyte Coculture Model for Assessment of Liver Toxicity Using High-Content Imaging Analysis
2014
Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver
2014
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
An integrated map of genetic variation from 1,092 human genomes
2012 StandoutNature
Occupational safety and health, green chemistry, and sustainability: a review of areas of convergence
2013
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
Structural‐Deformation‐Energy‐Modulation Strategy in a Soft Porous Coordination Polymer with an Interpenetrated Framework
2020 StandoutNobel
Mitochondrial uncoupling and lifespan
2010
Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption
2011
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Development of a Microscale Cell Culture Analog To Probe Naphthalene Toxicity
2004
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase
2017
Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian Cells
2016
Diabetes associated cell stress and dysfunction: role of mitochondrial and non‐mitochondrial ROS production and activity
2007
Activation of NRF2 by Nitrosative Agents and H2O2 Involves KEAP1 Disulfide Formation
2010
Tissue distribution, metabolism, and elimination of perfluorooctanoic acid in male and female rats
1991
Pharmacokinetics, Metabolism, and Carcinogenicity of Arsenic
2001
Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity
2016
A Toxicology for the 21st Century—Mapping the Road Ahead
2009
Chlorinated volatile organic compounds (Cl-VOCs) in environment — sources, potential human health impacts, and current remediation technologies
2014
Cells on chips
2006 StandoutNature
Chemistry, Biochemistry, and Safety of Acrylamide. A Review
2003 Standout
The KEAP1–NRF2 System in Cancer
2017
Ce-Duox1/BLI-3 Generated Reactive Oxygen Species Trigger Protective SKN-1 Activity via p38 MAPK Signaling during Infection in C. elegans
2011
Gene–environment-wide association studies: emerging approaches
2010
Comparison of Microarrays and RNA-Seq for Gene Expression Analyses of Dose-Response Experiments
2013
Biocompatibility of Immobilized Aligned Carbon Nanotubes
2011
A diet rich in high-glucoraphanin broccoli interacts with genotype to reduce discordance in plasma metabolite profiles by modulating mitochondrial function
2013
The Design and Fabrication of Three-Chamber Microscale Cell Culture Analog Devices with Integrated Dissolved Oxygen Sensors
2004
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines
2000
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure
2013
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax
2013
The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma
2012
The Hallmarks of Aging
2013 Standout
Toxicology for the twenty-first century
2009 StandoutNature
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Perfluoroalkyl sulfonic and carboxylic acids: A critical review of physicochemical properties, levels and patterns in waters and wastewaters, and treatment methods
2009
The NCATS BioPlanet – An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics
2019
Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress
2017
Microengineered Liver Tissues for Drug Testing
2015
Critical analysis of literature on low-dose synergy for use in screening chemical mixtures for risk assessment
2011
Therapeutic dose as the point of departure in assessing potential health hazards from drugs in drinking water and recycled municipal wastewater
2010
Identification of Chemical Compounds that Induce HIF-1α Activity
2009 StandoutNobel
Biological Chemistry of Carbon Monoxide
2002
Nrf2, the Master Regulator of Anti-Oxidative Responses
2017
Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism
2016
Efficient Synthesis of Primary Nitrocarbamates of Sugar Alcohols: From Food to Energetic Materials
2015
Structural patterns in globular proteins
1976 StandoutNatureNobel
Biochemistry of Nitric Oxide and Its Redox-Activated Forms
1992 StandoutScience
Advances in engineering hydrogels
2017 StandoutScience
Kinetics of Oxygen Binding to Human Hemoglobin
1974
Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications
2019 Standout
Make better, safer biomaterials
2016 Nature
Urea Tolerance as a Molecular Adaptation of Elasmobranch Hemoglobins
1974 Science
Quaternary structure of partially liganded intermediates of sheep carbon monoxide hemoglobin at alkaline pH
1975
Differences in spectra of alpha and beta chains of hemoglobin between isolated state and in tetramer.
1975
Molecular and cellular basis for the unique functioning of Nrf1, an indispensable transcription factor for maintaining cell homoeostasis and organ integrity
2016
Future of ToxicologyLow-Dose Toxicology and Risk−Benefit Analysis
2006
The dawning of a new age of toxicology
2008
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Learning Drug Functions from Chemical Structures with Convolutional Neural Networks and Random Forests
2019
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Perfluorinated Carboxylic Acids in Directly Fluorinated High-Density Polyethylene Material
2011
Energy-structure correlation in metalloporphyrins and the control of oxygen binding by hemoglobin.
1977 StandoutNobel
Regulating the regulator: Factors that control levels and activity of the aryl hydrocarbon receptor
2006
Spectral differences between the alpha and beta heme groups within human deoxyhemoglobin.
1976
Nrf2 Protects Pancreatic β-Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice
2013
State-of-the-science of endocrine disrupting chemicals, 2012
2012
Influence of globin structure on the state of the heme. I. Human deoxyhemoglobin
1974
Formaldehyde Carcinogenicity Research
2012
Temporal Shifts in Poly- and Perfluoroalkyl Substances (PFASs) in North Atlantic Pilot Whales Indicate Large Contribution of Atmospheric Precursors
2017
PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field
2020
Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research
2020 Standout
Once-Weekly Semaglutide in Adults with Overweight or Obesity
2021 Standout
Immunotoxicity of Perfluorinated Compounds: Recent Developments
2011
Food Browning and Its Prevention: An Overview
1996
Role of Glutathione in Cancer Progression and Chemoresistance
2013
Regulate to reduce chemical mixture risk
2018 StandoutScience
PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps in Understanding
2020
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
The Ecology of Arsenic
2003 StandoutScience
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Carbon Nanotubes: Present and Future Commercial Applications
2013 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Biocompatible Nanoscale Dispersion of Single-Walled Carbon Nanotubes Minimizes in vivo Pulmonary Toxicity
2010
Bioaccumulation of Perfluorinated Alkyl Acids: Observations and Models
2014
Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases
2013
TOXICITY AND TOXICOKINETICS OF PERFLUOROOCTANOIC ACID IN HUMANS AND ANIMALS
2003
Myeloid Lineage–Specific Deletion of Antioxidant System Enhances Tumor Metastasis
2014
Rate of quaternary structure change in hemoglobin measured by modulated excitation.
1976 StandoutNobel
Enhancing the functional maturity of induced pluripotent stem cell–derived human hepatocytes by controlled presentation of cell–cell interactions in vitro
2014
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Structure and function of haemoglobin
1976
The Halogen Bond
2016 Standout
Applications and societal benefits of plastics
2009 Standout
Crystal structure analysis of sea lamprey hemoglobin at 2 Å resolution
1973 StandoutNobel
Metal–Organic Frameworks in Biomedicine
2011 Standout
A small angle x-ray scattering study of a rhodopsin-lipid complex in hexane.
1983 StandoutNobel
Per- and polyfluoroalkyl substances in the environment
2022 StandoutScience
ChatGPT Chemistry Assistant for Text Mining and the Prediction of MOF Synthesis
2023 StandoutNobel
Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies
2019 Science
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers
2007 Standout
A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways
2016
[38] Stopped-flow, rapid mixing measurements of ligand binding to hemoglobin and red cells
1981
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Living with Water Stress: Evolution of Osmolyte Systems
1982 StandoutScience
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
The Reaction of n-Butyl Isocyanide with Human Hemoglobin
1971
Dispelling urban myths about default uncertainty factors in chemical risk assessment – sufficient protection against mixture effects?
2013
De novo design of protein logic gates
2020 StandoutScienceNobel
Discovery of an NRF 1‐specific inducer from a large‐scale chemical library using a direct NRF 1‐protein monitoring system
2015
Serum Concentrations of 11 Polyfluoroalkyl Compounds in the U.S. Population: Data from the National Health and Nutrition Examination Survey (NHANES) 1999−2000
2007
Works of Melvin E. Andersen being referenced
Physiological model for tissue glutathione depletion and increased resynthesis after ethylene dichloride exposure.
1988
Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys—Probing the determinants of long plasma half-lives
2006
Inhaled carbon nanotubes reach the subpleural tissue in mice
2009
Genomic Signatures and Dose-Dependent Transitions in Nasal Epithelial Responses to Inhaled Formaldehyde in the Rat
2008
Non-monotonic dose–response relationship in steroid hormone receptor-mediated gene expression
2007
Evaluation of Potential Toxicity from Co-Exposure to Three CNS Depressants (Toluene, Ethylbenzene, and Xylene) Under Resting and Working Conditions Using PBPK Modeling
2005
Formaldehyde: Integrating Dosimetry, Cytotoxicity, and Genomics to Understand Dose-Dependent Transitions for an Endogenous Compound
2010
In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI
2012
Physiologically based pharmacokinetic and pharmacodynamic model for the inhibition of acetylcholinesterase by diisopropyfluorophosphate
1990
Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling
2007
Integrating pathway-based transcriptomic data into quantitative chemical risk assessment: A five chemical case study
2012
Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment
2013
Dose Response Relationship in Anti-Stress Gene Regulatory Networks
2007
Workshop Overview: Reassessment of the Cancer Risk of Dichloromethane in Humans
2006
Quantitative Interpretation of Human Biomonitoring Data
2008
A Physiologically Based Pharmacokinetic Model for Acrylamide and Its Metabolite, Glycidamide, in the Rat
2003
Toxicity Testing in the 21st Century: Bringing the Vision to Life
2008
Biological regulation of receptor-hormone complex concentrations in relation to dose-response assessments for endocrine-active compounds
1999
An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy
2016
Time dependencies in perfluorooctylacids disposition in rat and monkeys: A kinetic analysis
2007
A Method to Integrate Benchmark Dose Estimates with Genomic Data to Assess the Functional Effects of Chemical Exposure
2007
Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model
2001
Chemical mixture toxicology: from descriptive to mechanistic, and going on to in silico toxicology
2004
Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment
2010
Suppression of NRF2–ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells
2015
New directions in incidence–dose modeling
2005
Perfluoroalkyl Acids and Related Chemistries—Toxicokinetics and Modes of Action
2007
Organotypic liver culture models: Meeting current challenges in toxicity testing
2012
Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis
2011
Quantitative Analyses and Transcriptomic Profiling of Circulating Messenger Rnas As Biomarkers of Rat Liver Injury
2010
Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages
2009
A Biologically Based Dose-Response Model for Dietary Iodide and the Hypothalamic-Pituitary-Thyroid Axis in the Adult Rat: Evaluation of Iodide Deficiency
2008
Cross-Species Transcriptomic Analysis of Mouse and Rat Lung Exposed to Chloroprene
2012
Divergent Effects of Sulforaphane on Basal and Glucose-Stimulated Insulin Secretion in β-Cells: Role of Reactive Oxygen Species and Induction of Endogenous Antioxidants
2013
Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice
2018
CNC-bZIP Protein Nrf1-Dependent Regulation of Glucose-Stimulated Insulin Secretion
2015
The Kinetics of Ligand Binding and of the Association-Dissociation Reactions of Human Hemoglobin
1971
Reply to Invited Commentaries on Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment
2009
Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment
2008
Development of Pbpk Models for Pfoa and Pfos for Human Pregnancy and Lactation Life Stages
2012
Requirements for a Biologically Realistic Cancer Risk Assessment for Inorganic Arsenic
1999
The acute toxicity of perfluorooctanoic and perfluorodecanoic acids in male rats and effects on tissue fatty acids
1983
Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome
2012
Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants for two independent pathways
1986
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks
2013
Incorporating Human Dosimetry and Exposure into High-ThroughputIn VitroToxicity Screening
2010
An approach to mechanism-based cancer risk assessment for formaldehyde.
1993
Associations of Perfluoroalkyl Substances (PFAS) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)
2015
The Dissociation of the First Oxygen Molecule from Some Mammalian Oxyhemoglobins
1971
Reactive Oxygen Species as a Signal in Glucose-Stimulated Insulin Secretion
2007
Long Isoforms of NRF1 Contribute to Arsenic-Induced Antioxidant Response in Human Keratinocytes
2010
A consistent approach for the application of pharmacokinetic modeling in cancer and noncancer risk assessment.
2002
Physiologically based pharmacokinetic model for the inhibition of acetylcholinesterase by organophosphate esters.
1994
Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells
2012
Long‐Term Stability of Primary Rat Hepatocytes in Micropatterned Cocultures
2013
Bioactivation and Toxicity of Acetaminophen in a Rat Hepatocyte Micropatterned Coculture System
2013
A Kinetic Analysis of the Binding of Oxygen and Carbon Monoxide to Lamprey Hemoglobin
1971
Cross-Regulations among NRFs and KEAP1 and Effects of their Silencing on Arsenic-Induced Antioxidant Response and Cytotoxicity in Human Keratinocytes
2012