Citation Impact
Citing Papers
CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer
2013
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
2007 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Linking functional decline of telomeres, mitochondria and stem cells during ageing
2010 Nature
The DNA-damage response in human biology and disease
2009 StandoutNature
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
2006
Cellular and Gene Expression Responses Involved in the Rapid Growth Inhibition of Human Cancer Cells by RNA Interference-mediated Depletion of Telomerase RNA
2005 StandoutNobel
The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells
2012
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
2005 StandoutNature
Evolution of the cancer genome
2012
Loss of miR-10a Activates Lpo and Collaborates with Activated Wnt Signaling in Inducing Intestinal Neoplasia in Female Mice
2013
Cancer Metastasis: Building a Framework
2006 Standout
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice
2007
Different telomere damage signaling pathways in human and mouse cells
2002
Human Hepatocyte Transplantation: Worldwide Results
2006
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Putting the stress on senescence
2001
Telomeres and telomerase in cancer
2009
Telomerase Deletion Limits Progression of p53-Mutant Hepatocellular Carcinoma With Short Telomeres in Chronic Liver Disease
2007
Telomeres and telomerase: A dual role in hepatocarcinogenesis
2004
Telomerase Antagonists GRN163 and GRN163L Inhibit Tumor Growth and Increase Chemosensitivity of Human Hepatoma *
2005
Cancer Modeling in the Modern Era
2002
Natural and pharmacological regulation of telomerase
2002
Mitochondria‐Targeted Cancer Therapy Using a Light‐Up Probe with Aggregation‐Induced‐Emission Characteristics
2014
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Telomere dysfunction and the initiation of genome instability
2003 StandoutNobel
Epigenetics in Cancer
2008 Standout
Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence
2007 StandoutNobel
Telomere length, stem cells and aging
2007
The telomere syndromes
2012 Nobel
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
2006 StandoutNobel
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Hallmarks of senescence in carcinogenesis and cancer therapy
2004
How stem cells age and why this makes us grow old
2007
Telomeres and cancer: a tale with many endings
2003
Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis†
2007
Metazoan MicroRNAs
2018 Standout
In situ analyses of genome instability in breast cancer
2004
Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation
2005 StandoutNobel
Conditional mouse models of sporadic cancer
2002
Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma
2004
Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression
2003
Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging
2009 StandoutNobel
Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells
2003
p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice
2009
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Liver regeneration: from myth to mechanism
2004
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma
2015
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
Cytokinesis-block micronucleus cytome assay
2007 Standout
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury
2018 Nature
The role of senescent cells in ageing
2014 StandoutNature
Telomeres and human disease: ageing, cancer and beyond
2005
Induction of hepatocyte proliferation and liver hyperplasia by the targeted expression of cyclin E and skp2
2001
The Hallmarks of Aging
2013 Standout
The age of cancer
2000 Nature
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis
2002 StandoutNobel
Telomerase: A target for cancer therapeutics
2002
Hepatocellular Carcinoma
2011 Standout
Frailty in elderly people
2013 Standout
The cancer genome
2009 StandoutNature
Cell senescence and cancer
2001
The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo
2005
Clues from cell metabolism
2010 StandoutNatureNobel
Hepatocellular Carcinoma
2019 Standout
Karyotypic complexity of the NCI-60 drug-screening panel.
2003
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
2005
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Understanding Cell Penetration of Cyclic Peptides
2019
Telomeres: Cancer to Human Aging
2006
Whole chromosome loss is promoted by telomere dysfunction in primary cells
2010
Connecting Chromosomes, Crisis, and Cancer
2002 Science
Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma.
2003
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Broken Limits to Life Expectancy
2002 StandoutScience
Cellular Mechanisms of Tissue Fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis
2012
Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.
2003 StandoutNobel
RNA Display Methods for the Discovery of Bioactive Macrocycles
2018
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
2002
Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells
2000
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
DNA-Dependent Protein Kinase Catalytic Subunit Is Not Required for Dysfunctional Telomere Fusion and Checkpoint Response in the Telomerase-Deficient Mouse
2006
End Resection Initiates Genomic Instability in the Absence of Telomerase
2003 StandoutNobel
Works of Melissa Millard being referenced
Mechanistic Evaluation of a Novel Small Molecule Targeting Mitochondria in Pancreatic Cancer Cells
2013
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide
2013
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
2001
Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity
2010
Inhibition of Experimental Liver Cirrhosis in Mice by Telomerase Gene Delivery
2000 Science
A Selective Mitochondrial-Targeted Chlorambucil with Remarkable Cytotoxicity in Breast and Pancreatic Cancers
2013
c-Abl mediates endothelial apoptosis induced by inhibition of integrins αvβ3 and αvβ5 and by disruption of actin
2010