Citation Impact
Citing Papers
PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells
2010
Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers
2018 StandoutNobel
Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti–PD-1 Therapy
2014 Standout
Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function
2012
Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
2013
SA-4-1BBL and Monophosphoryl Lipid A Constitute an Efficacious Combination Adjuvant for Cancer Vaccines
2014
Tim-3 Expression on Tumor-Infiltrating PD-1+CD8+ T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma
2016
Chimeric antigen receptor -T cell therapy: Applications and challenges in treatment of allergy and asthma
2019
T cell exhaustion: from pathophysiological basics to tumor immunotherapy
2017
An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction
2015
T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment
2013
B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality
2015 StandoutNobel
Dendritic cells in cancer immunology and immunotherapy
2019 Standout
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion
2012
Determining cell type abundance and expression from bulk tissues with digital cytometry
2019 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
Emerging Tim-3 functions in antimicrobial and tumor immunity
2011
A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells
2016
Synovial Tissue Inflammation Mediated by Autoimmune T Cells
2019 StandoutNobel
Innate and adaptive immune cells in the tumor microenvironment
2013 Standout
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
2015
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
Immune evasion in acute myeloid leukemia: current concepts and future directions
2013
Coordinated regulation of myeloid cells by tumours
2012 Standout
Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes
2018 StandoutNobel
Immunogenic cell death in cancer and infectious disease
2016 Standout
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
2014 Standout
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
2016 StandoutNobel
Tumor-Associated Macrophages: From Mechanisms to Therapy
2014 Standout
Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
2012
Next generation immune-checkpoints for cancer therapy
2018
Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma
2012
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
2012
Feasibility and Safety of RNA-transfected CD20-specific Chimeric Antigen Receptor T Cells in Dogs with Spontaneous B Cell Lymphoma
2016
PD-L1 (CD274) promoter methylation predicts survival in patients with acute myeloid leukemia
2016
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
2017 Standout
Emerging targets in cancer immunotherapy
2017
Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs
2012
T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment
2015
Periodontitis: from microbial immune subversion to systemic inflammation
2014 Standout
The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?
2015
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
2016 Standout
Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
2012
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma
2012
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
2016 Standout
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
2017 Standout
Combination cancer immunotherapies tailored to the tumour microenvironment
2015
Interferon-β Suppresses Murine Th1 Cell Function in the Absence of Antigen-Presenting Cells
2015
Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer
2017 StandoutNobel
Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury
2012
Autocrine Adenosine Signaling Promotes Regulatory T Cell–Mediated Renal Protection
2012
The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies
2013
Immune Checkpoint Proteins: A New Therapeutic Paradigm for Cancer—Preclinical Background: CTLA-4 and PD-1 Blockade
2010
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)
2016
TIM3+FOXP3+regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer
2013
Targeting Immune Checkpoints in Hematologic Malignancies
2016
Immune Checkpoint Protein Inhibition for Cancer: Preclinical Justification for CTLA-4 and PD-1 Blockade and New Combinations
2015
The Emerging Role of In Vitro-Transcribed mRNA in Adoptive T Cell Immunotherapy
2019 StandoutNobel
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
2018 Standout
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Role of the PD-1 Pathway in the Immune Response
2012
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Immune Modulation in Cancer with Antibodies
2013 StandoutNobel
The Influence of T Cell Ig Mucin-3 Signaling on Central Nervous System Autoimmune Disease Is Determined by the Effector Function of the Pathogenic T Cells
2013
Strength of PD-1 signaling differentially affects T-cell effector functions
2013
T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production
2012
Both PD-1 Ligands Protect the Kidney from Ischemia Reperfusion Injury
2014
The emerging role of immune checkpoint based approaches in AML and MDS
2017 StandoutNobel
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Generation of allo-antigen-specific induced Treg stabilized by vitamin C treatment and its application for prevention of acute graft versus host disease model
2017
Induction of cancer testis antigen expression in circulating acute myeloid leukemia blasts following hypomethylating agent monotherapy
2016
Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?
2011
The role of B7 family molecules in hematologic malignancy
2012
CD40 ligation reverses T cell tolerance in acute myeloid leukemia
2013
Chimeric Antigen Receptor Therapy
2018 Standout
Durable Cancer Regression Off-Treatment and Effective Reinduction Therapy with an Anti-PD-1 Antibody
2012
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
2012
Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell–Mediated Killing
2013
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer
2013
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma
2014 Standout
Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice
2014 Standout
Immune Checkpoint Blockade in Cancer Therapy
2015 Standout
Restoring Immune Function of Tumor-Specific CD4+ T Cells during Recurrence of Melanoma
2013
Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis
2020 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Leukemia cell–targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity
2013
Works of Meghan E. Munger being referenced
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia
2010
IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation
2009
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
2011
Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia
2009