Citation Impact
Citing Papers
Acquired Immunity to Malaria
2009
Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein
2017
Discovery, mechanisms of action and combination therapy of artemisinin
2009 Standout
Cutting Edge: A New Tool to Evaluate Human Pre-Erythrocytic Malaria Vaccines: Rodent Parasites Bearing a Hybrid Plasmodium falciparum Circumsporozoite Protein
2002
A mosquito AgTRIO mRNA vaccine contributes to immunity against malaria
2023 StandoutNobel
Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection
2017
Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice
2021 StandoutNobel
Plasmodium falciparum pre-erythrocytic stage vaccine development
2020
Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data
2009
Comparison of immunogenicity and safety outcomes of a malaria vaccine FMP013/ALFQ in rhesus macaques (Macaca mulatta) of Indian and Chinese origin
2019
Gene Disruption of Plasmodium falciparum p52 Results in Attenuation of Malaria Liver Stage Development in Cultured Primary Human Hepatocytes
2008
Advance market commitments for vaccines against neglected diseases: estimating costs and effectiveness
2006 StandoutNobel
Messenger RNA-Based Vaccines Against Infectious Diseases
2020 StandoutNobel
The March Toward Malaria Vaccines
2015
Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine
2017
Study of hepatitis C virus entry in genetically humanized mice
2012 StandoutNobel
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines
2013 StandoutNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope
2012
Longitudinal transcriptomic characterization of the immune response to acute hepatitis C virus infection in patients with spontaneous viral clearance
2018 StandoutNobel
Intravital microscopy demonstrating antibody-mediated immobilisation of Plasmodium berghei sporozoites injected into skin by mosquitoes
2004
The role of liposomes in clinical nanomedicine development. What now? Now what?
2019 Standout
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
2023 StandoutNobel
Manipulation of apoptosis in the host–parasite interaction
2004
Recent clinical experience with vaccines using MPL- and QS-21-containing Adjuvant Systems
2011
Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial
2001
Liver‐Stage Development ofPlasmodium falciparum,in a Humanized Mouse Model
2006
Hydroxychloroquine: From Malaria to Autoimmunity
2011 Standout
Global Distribution of Alveolar and Cystic Echinococcosis
2017 Standout
Towards an optimized inhibition of liver stage development assay (ILSDA) for Plasmodium falciparum
2013
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
2006 StandoutNature
Superior immunogenicity of HCV envelope glycoproteins when adjuvanted with cyclic-di-AMP, a STING activator or archaeosomes
2017 StandoutNobel
Murine Cerebral Malaria Development Is Independent of Toll-Like Receptor Signaling
2007 StandoutNobel
Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates
2015
Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120, Nef and Tat antigens formulated in three Adjuvant Systems
2010
Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice
2018
Development of an AS04-Adjuvanted HPV Vaccine with the Adjuvant System Approach
2011
mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum
2022 StandoutNobel
Evaluation of RTS,S/AS02A and RTS,S/AS01B in Adults in a High Malaria Transmission Area
2009
The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum
2003 Standout
Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies
2013
IMRAS—Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS
2021
Identification and Characterization of the Host Protein DNAJC14 as a Broadly Active Flavivirus Replication Modulator
2011 StandoutNobel
Vaccine Adjuvants: Putting Innate Immunity to Work
2010
The RTS,S malaria vaccine
2010
Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults
2015 Standout
Improved T cell responses to Plasmodium falciparum circumsporozoite protein in mice and monkeys induced by a novel formulation of RTS,S vaccine antigen
2008
Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection
2016
Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS
2022 StandoutNobel
Malaria
2013 Standout
Vaccine adjuvants – understanding molecular mechanisms to improve vaccines
2014 StandoutNobel
Safety, toxicity and immunogenicity of a malaria vaccine based on the circumsporozoite protein (FMP013) with the adjuvant army liposome formulation containing QS21 (ALFQ)
2019
Pre-erythrocytic malaria vaccines: towards greater efficacy
2005
A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T‐cell immunity in vivo
2011 StandoutNobel
Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies
2017
Save the children
2004 Nature
Liposomes containing monophosphoryl lipid A and QS-21 serve as an effective adjuvant for soluble circumsporozoite protein malaria vaccine FMP013
2017
A Phase 1/2 Clinical Trial Evaluating Safety and Immunogenicity of a Varicella Zoster Glycoprotein E Subunit Vaccine Candidate in Young and Older Adults
2012
Induction of specific immune responses against the Plasmodium vivax liver-stage via in vitro activation by dendritic cells
2006
Plasmepsin 4-Deficient Plasmodium berghei Are Virulence Attenuated and Induce Protective Immunity against Experimental Malaria
2009
A Full-Length Plasmodium falciparum Recombinant Circumsporozoite Protein Expressed by Pseudomonas fluorescens Platform as a Malaria Vaccine Candidate
2014
Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers
2008
Pre-erythrocytic malaria vaccines: identifying the targets
2012
Innate sensing of malaria parasites
2014
Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity
2019
Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates
2010 StandoutNobel
Vaccines for parasitic and bacterial diseases
2003
Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
2012
A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
2012
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
2007 Standout
Safety and immunogenicty of RTS,S/AS02A candidate malaria vaccine in Gambian children
2005
A multilateral effort to develop DNA vaccines against falciparum malaria
2002
Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant
2003
Requirements for high impact diagnostics in the developing world
2006 StandoutNature
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites
2014
The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity
2016
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
2018 StandoutNobel
Pre-clinical evaluation of the malaria vaccine candidate . MSP1 formulated with novel adjuvants or with alum
2004
The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites
2006 Nature
Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsonophagocytosis
2017
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against the murine malarial parasite Plasmodium yoelii
2010 StandoutNobel
Plasmodium vivax Cell-Traversal Protein for Ookinetes and Sporozoites: Naturally Acquired Humoral Immune Response and B-Cell Epitope Mapping in Brazilian Amazon Inhabitants
2017
Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis
2014 Standout
A CD4+ T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease
2004
The Case for Exploiting Cross-Species Epitopes in Malaria Vaccine Design
2020
IgG2 Antibodies against a Clinical Grade Plasmodium falciparum CSP Vaccine Antigen Associate with Protection against Transgenic Sporozoite Challenge in Mice
2014
Antimalarial Drug Toxicity
2004
Phase 1 Evaluation of 3 Highly Immunogenic Prime‐Boost Regimens, Including a 12‐Month Reboosting Vaccination, for Malaria Vaccination in Gambian Men
2004
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Novel sporozoite-based ELISpot assay to assess frequency of parasite-specific B cells after vaccination with irradiated sporozoites
2019
From discovery to licensure, the Adjuvant System story
2016
Synthesis, Characterization, and in vitro Antimalarial and Antitumor Activity of New Ruthenium(II) Complexes of Chloroquine
2009
RTS,S/AS01 vaccine (Mosquirix™): an overview
2019
Genetically modified Plasmodium parasites as a protective experimental malaria vaccine
2004 Nature
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Optimization of aPlasmodium falciparumcircumsporozoite protein repeat vaccine using the tobacco mosaic virus platform
2020
Phase I Testing of a Malaria Vaccine Composed of Hepatitis B Virus Core Particles ExpressingPlasmodium falciparumCircumsporozoite Epitopes
2004
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Organometallic Anticancer Compounds
2010 Standout
UPDATE ON THE CLINICAL DEVELOPMENT OF CANDIDATE MALARIA VACCINES
2004
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
2016
Pre-clinical evaluation of new adjuvant formulations to improve the immunogenicity of the malaria vaccine RTS,S/AS02A
2006
Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein
2004
Orientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity
2021
Broadly neutralizing antibodies abrogate established hepatitis C virus infection
2014 StandoutNobel
ESTIMATING RELATEDNESS USING GENETIC MARKERS
1989 Standout
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Identification ofPlasmodium falciparumantigens by antigenic analysis of genomic and proteomic data
2003
The RTS,S malaria vaccine: Current impact and foundation for the future
2022
CONQUERING THE INTOLERABLE BURDEN OF MALARIA: WHAT’S NEW, WHAT’S NEEDED: A SUMMARY
2004
Vaccine innovations for emerging infectious diseases—a symposium report
2019 StandoutNobel
Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research
2005
Approaches to Malaria Vaccine Development Using the Retrospectroscope
2009
Yellow fever 17D as a vaccine vector for microbial CTL epitopes
2005 StandoutNobel
Young Lives Lost as B Cells Falter: What We Are Learning About Antibody Responses in Malaria
2013
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells
2005 Standout
Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption
2016
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
2004 StandoutNobel
Protective Immunity Induced with Malaria Vaccine, RTS,S, Is Linked to Plasmodium falciparum Circumsporozoite Protein-Specific CD4+ and CD8+ T Cells Producing IFN-γ
2003
Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model
2017 StandoutNobel
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
Effect of Different Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins
2019 StandoutNobel
Vaccine Adjuvants: from 1920 to 2015 and Beyond
2015
Challenges and strategies for developing efficacious and long-lasting malaria vaccines
2019
Towards a small animal model for hepatitis C
2009 StandoutNobel
Adjuvant system AS01: helping to overcome the challenges of modern vaccines
2016
Comparative study of genetic and social structure in two forms of the fire ant Solenopsis invicta (Hymenoptera: Formicidae)
1985
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
2006 StandoutNobel
Systems analysis of protective immune responses to RTS,S malaria vaccination in humans
2017
Enhancement of Adaptive Immunity by the Human Vaccine Adjuvant AS01 Depends on Activated Dendritic Cells
2014
Pre-Erythrocytic Vaccines against Malaria
2020
Priming with an Adenovirus 35-Circumsporozoite Protein (CS) Vaccine followed by RTS,S/AS01B Boosting Significantly Improves Immunogenicity toPlasmodium falciparumCS Compared to That with Either Malaria Vaccine Alone
2007
Transgenic Parasites Stably Expressing Full-Length Plasmodium falciparum Circumsporozoite Protein as a Model for Vaccine Down-Selection in Mice Using Sterile Protection as an Endpoint
2013
Works of Megan Dowler being referenced
Protection of Humans against Malaria by Immunization with Radiation‐AttenuatedPlasmodium falciparumSporozoites
2002
Efficacy of Recombinant Circumsporozoite Protein Vaccine Regimens against ExperimentalPlasmodium falciparumMalaria
2001
Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection
2009
Causal prophylactic efficacy of atovaquone-proguanil (MalaroneTM) in a human challenge model
2001
Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research
2008
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design
2009
ELECTROPHORETIC VARIANTS OF α-GLYCEROPHOSPHATE DEHYDROGENASE IN THE FIRE ANTSOLENOPSIS INVICTA
1979