Citation Impact
Citing Papers
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
2012 Standout
Fetal Hemoglobin, Sickling, and Sickle Cell Disease
1990
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Senegal haplotype is associated with higher HbF than benin and cameroon haplotypes in African children with sickle cell anemia
1993
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
Enhanced Adherence of Sickle Erythrocytes to Thrombin-Treated Endothelial Cells Involves Interendothelial Cell Gap Formation
1998
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
2015 StandoutNobel
How Malaria Has Affected the Human Genome and What Human Genetics Can Teach Us about Malaria
2005
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
Pathophysiology of Progressive Nephropathies
1998 Standout
Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase
2009 StandoutNobel
Evidence that fibroblasts derive from epithelium during tissue fibrosis
2002 Standout
Pathogenesis and Treatment of Sickle Cell Disease
1997
Ion Transport Pathology in the Mechanism of Sickle Cell Dehydration
2004
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
The Influence of Macromolecular Crowding and Macromolecular Confinement on Biochemical Reactions in Physiological Media
2001 Standout
The β-Thalassemias
1999 Standout
Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia
1995 Standout
Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice
2004
Hypoxaemia in sickle cell disease: biomarker modulation and relevance to pathophysiology
2003
Sickle Cell Trait and the Risk ofPlasmodium falciparumMalaria and Other Childhood Diseases
2005
Cellular effects of hydroxyurea in Hb SC disease
1997
Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice
2000
Lethal α–thalassaemia created by gene targeting in mice and its genetic rescue
1995
Evaluation of a Density-Based Rapid Diagnostic Test for Sickle Cell Disease in a Clinical Setting in Zambia
2014
Clinical management of adult sickle-cell disease
2012
Gender and haplotype effects upon hematological manifestations of adult sickle cell anemia
1995
Sickle Hemoglobin Confers Tolerance to Plasmodium Infection
2011
NOVEL TREATMENT OPTIONS IN THE SEVERE β‐GLOBIN DISORDERS
1995
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Regulation of Cell Volume in Health and Disease
1995
Unusually large von willebrand factor multimers preferentially promote young sickle and nonsickle erythrocyte adhesion to endothelial cells
1993
Diabetes and Atherosclerosis
2002 Standout
Investigational drugs in sickle cell anemia
2009
Charybdotoxin blocks with high affinity the Ca-activated K+ channel of Hb A and Hb S red cells: Individual differences in the number of channels
1988
Sickle Cell Hemoglobin Polymerization
1990
The pathogenic basis of malaria
2002 StandoutNature
Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography
1998 Standout
Sickle-cell disease
2010 Standout
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
Elevated Pulse Pressure is Associated with Hemolysis, Proteinuria and Chronic Kidney Disease in Sickle Cell Disease
2014
Deconstructing sickle cell disease: Reappraisal of the role of hemolysis in the development of clinical subphenotypes
2006
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Stroke risk in siblings with sickle cell anemia
2003
The basics of epithelial-mesenchymal transition
2009 Standout
Hypernatremia
2000 Standout
Therapeutic Strategies for Prevention of Sickle Cell Dehydration
2001
Biomarkers for epithelial-mesenchymal transitions
2009 Standout
Sickle cell disease in Africa: burden and research priorities
2007
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
The paradox of hemoglobin SC disease
2003
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
2013 StandoutNobel
Red cell indices in classification and treatment of anemias
2013
Stroke in a cohort of patients with homozygous sickle cell disease
1992
The Human Condition—A Molecular Approach
2014 StandoutNobel
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
Whole-genome molecular haplotyping of single cells
2010
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
Sickle cell vaso-occlusion: multistep and multicellular paradigm
2002
A potent oral P‐selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease
2012
Arginine Therapy
2003
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology
1991
STILBOESTROL AND STUTTERING PRIAPISM IN HOMOZYGOUS SICKLE-CELL DISEASE
1985
Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor
1997
Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity
2002
Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease
2003
Decrease of Very Late Activation Antigen-4 and CD36 on Reticulocytes in Sickle Cell Patients Treated With Hydroxyurea
1997
Supramolecular Polymerization
2009 Standout
HIF–prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques
2007
Anionic Polysaccharides Inhibit Adhesion of Sickle Erythrocytes to the Vascular Endothelium and Result in Improved Hemodynamic Behavior
1999
Mutant Potassium Channels with Altered Binding of Charybdotoxin, a Pore-Blocking Peptide Inhibitor
1989 StandoutScienceNobel
Hemostatic Alterations in Sickle Cell Disease: Relationships to Disease Pathophysiology
2001
A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy
1996
Crystallization by particle attachment in synthetic, biogenic, and geologic environments
2015 StandoutScience
Effects of hydroxyurea on hemoglobin F and water content in the red blood cells of dogs and of patients with sickle cell anemia
1991
Foetal Haemoglobin, Erythrocytes Containing Foetal Haemoglobin, and Hematological Features in Congolese Patients with Sickle Cell Anaemia
2012
Monoclonal antibodies to αVβ3 (7E3 and LM609) inhibit sickle red blood cell–endothelium interactions induced by platelet-activating factor
2000
Blood Polymorphonuclear Leukocytes From the Majority of Sickle Cell Patients in the Crisis Phase of the Disease Show Enhanced Adhesion to Vascular Endothelium and Increased Expression of CD64
1998
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Evidence that fibroblasts derive from epithelium during tissue fibrosis
2002 Standout
Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin
2004
The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry
1993 StandoutNobel
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease
2010
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Uncoupling of the Spectrin-Based Skeleton from the Lipid Bilayer in Sickled Red Cells
1991 Science
Introduction: anti-adhesion therapy in sickle cell disease
2000
An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration.
1994
P-selectin mediates the adhesion of sickle erythrocytes to the endothelium
2001
Heparin inhibits the flow adhesion of sickle red blood cells to P-selectin
2002
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Sickle cell disease and stroke
2009
Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells
1992
Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease.
1999
A Common Human β Globin Splicing Mutation Modeled in Mice
1998 StandoutNobel
Transgenic sickle mice have vascular inflammation
2003
Membrane Transport in Sickle Cell Disease
2002
Kinetics of sickle hemoglobin polymerization
1985
Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells.
1995
Hematologically and Genetically Distinct Forms of Sickle Cell Anemia in Africa
1985
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
2007 StandoutNobel
Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow.
1987
Kinetics of sickle hemoglobin polymerization
1985
Primary role for adherent leukocytes in sickle cell vascular occlusion: A new paradigm
2002
Alpha 4 beta 1-integrin expression on sickle reticulocytes: vascular cell adhesion molecule-1-dependent binding to endothelium
1993
Iron-Deficiency Anemia
2015 Standout
Ameliorating effects of fluorocarbon emulsion on sickle red blood cell–induced obstruction in an ex vivo vasculature
2001
A mouse model for beta 0-thalassemia.
1995 StandoutNobel
Reperfusion injury pathophysiology in sickle transgenic mice
2000
Liquid–liquid separation in solutions of normal and sickle cell hemoglobin
2002
Density-based separation in multiphase systems provides a simple method to identify sickle cell disease
2014
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Acute priapism associated with the use of sildenafil in a patient with sickle cell trait
2000
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Oral magnesium pidolate: effects of long‐term administration in patients with sickle cell disease
2000
Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics
2010 StandoutNobel
Sickle cell disease of transgenic SAD mice
1994
Delay Time of Hemoglobin S Polymerization Prevents Most Cells from Sickling in Vivo
1987 Science
An analysis of fetal hemoglobin variation in sickle cell disease: the relative contributions of the X-linked factor, beta-globin haplotypes, alpha-globin gene number, gender, and age
1995
HbS-Oman Heterozygote: A New Dominant Sickle Syndrome
1998
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel
Integrin alpha 4 beta 1 and glycoprotein IV (CD36) are expressed on circulating reticulocytes in sickle cell anemia
1993
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Works of ME Fabry being referenced
An objective sign in painful crisis in sickle cell anemia: the concomitant reduction of high density red cells
1984
Paradoxical increase of painful crises in sickle cell patients with alpha-thalassemia [letter; comment]
1995
The effect of deoxygenation on red cell density: significance for the pathophysiology of sickle cell anemia
1982
Vaso-occlusion by sickle cells: evidence for selective trapping of dense red cells
1986
The Senegal DNA haplotype is associated with the amelioration of anemia in African-American sickle cell anemia patients
1991
SC erythrocytes have an abnormally high intracellular hemoglobin concentration. Pathophysiological consequences.
1982
F reticulocyte response in sickle cell anemia treated with recombinant human erythropoietin: a double-blind study
1993
Vaso-occlusion by sickle cells: evidence for selective trapping of dense red cells
1986
Microvascular sites and characteristics of sickle cell adhesion to vascular endothelium in shear flow conditions: pathophysiological implications.
1989
Rapid increase in red blood cell density driven by K:Cl cotransport in a subset of sickle cell anemia reticulocytes and discocytes
1991
F reticulocyte response in sickle cell anemia treated with recombinant human erythropoietin: a double-blind study
1993
Rapid increase in red blood cell density driven by K:Cl cotransport in a subset of sickle cell anemia reticulocytes and discocytes
1991
Dense cells in sickle cell anemia: the effects of gene interaction
1984
The unique red cell heterogeneity of SC disease: crystal formation, dense reticulocytes, and unusual morphology
1991
The hematologic characteristics of sickle cell anemia bearing the Bantu haplotype: the relationship between G gamma and HbF level
1987
Red cell distribution width parallels dense red cell disappearance during painful crises in sickle cell anemia.
1985
Deoxygenation inhibits the volume-stimulated, Cl(-)-dependent K+ efflux in SS and young AA cells: a cytosolic Mg2+ modulation
1987
Demonstration of endothelial adhesion of sickle cells in vivo: a distinct role for deformable sickle cell discocytes
1992
High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences.
1992
Immunohistochemical localization of hepatic nitric oxide synthase in normal and transgenic sickle cell mice: the effect of hypoxia
1996
Protection from lethal malaria in transgenic mice expressing sickle hemoglobin
1996
Transgenic mice expressing human sickle hemoglobin are partially resistant to rodent malaria
1993