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Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
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Functional diversity of helper T lymphocytes
1996 StandoutNature
Airways inflammationin asthma and chronic bronchitis
1996
Different cytokine patterns in bronchial biopsies in asthma and chronic bronchitis
1996
Increased number of activated lymphocytes in human lung following swine dust inhalation
1997
Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy.
1997
Chimerism of the Transplanted Heart
2002 Standout
Remodeling of asthmatic airways by glucocorticosteroids
1996
Atopic Dermatitis
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Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophage-colony-stimulating factor, and IL-3.
1997
Inflammatory and T-cell profile of asthmatic airways 6 hours after local allergen provocation.
1996
T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma.
1996
The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates
1996 Standout
Airway structure and inflammatory cells in fatal attacks of asthma
1996
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes
1997 StandoutNobel
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Maintenance of functional equivalence during paralogous Hox gene evolution
2000 StandoutNatureNobel
Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial
2003
Early identification of interleukin-16 (lymphocyte chemoattractant factor) and macrophage inflammatory protein 1 alpha (MIP1 alpha) in bronchoalveolar lavage fluid of antigen-challenged asthmatics.
1995
Th1/Th2 Cells
1999
The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases
2002 Standout
The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics
1997
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
1997 Standout
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Chemokines — Chemotactic Cytokines That Mediate Inflammation
1998 Standout
Paraneoplastic Syndromes Involving the Nervous System
2003 Standout
Mediator and cytokine mechanisms in asthma.
1993
Chemokines and their receptors in allograft rejection
2000
Leukotrienes in the Pathogenesis of Asthma
1997
PCR-survey of hox-genes of the zebrafish: New sequence information and evolutionary implications
1996
Results of a Home-Based Environmental Intervention among Urban Children with Asthma
2004 Standout
Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine
2003
A role for the C3a anaphylatoxin receptor in the effector phase of asthma
2000 Nature
Prednisolone Treatment in Asthma Is Associated with Modulation of Bronchoalveolar Lavage Cell Interleukin-4, Interleukin-5, and Interferon-γ Cytokine Gene Expression
1993
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
Asthma
1992
Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics.
1992
Activated T-Lymphocytes and Macrophages in Bronchial Mucosa of Subjects with Chronic Bronchitis
1993
Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
2009 Standout
CD4 T-Lymphocyte Activation in Asthma Is Accompanied by Increased Serum Concentrations of Interleukin-5: Effect of Glucocorticoid Therapy
1993
Cytokines in asthma
1999
Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co‐localization of eotaxin mRNA to bronchial epithelial and endothelial cells
1997
Induction of nitric oxide synthase in asthma
1993
Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma
1994
Danger signals: SOS to the immune system
2001
Identification of T lymphocytes, Macrophages, and Activated Eosinophils in the Bronchial Mucosa in Intrinsic Asthma: Relationship to Symptoms and Bronchial Responsiveness
1992
High-affinity IgE receptor (FcepsilonRI)-bearing cells in bronchial biopsies from atopic and nonatopic asthma.
1996
Airway Mucosal Inflammation Even in Patients with Newly Diagnosed Asthma
1993
Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease
1993
Comparative analysis of chicken Hoxb-4 regulation in transgenic mice
1995
Molecular pathology of allergic disease
2000
Granulocyte macrophage colony-stimulating factor contributes to enhanced monocyte survival in chronic atopic dermatitis.
1995
A Study to Evaluate Safety and Efficacy of Mepolizumab in Patients with Moderate Persistent Asthma
2007
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system
1993
Anti-inflammatory effects of low-dose oral theophylline in atopic asthma
1994
Cyclosporine A inhibits airway reactivity and remodeling after chronic antigen challenge in cats.
1996
The development of allergic inflammation
2008 StandoutNature
Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
1997
“Helper” (CD4 + ) T Cells and Eosinophils in Allergy and Asthma
1992
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
2001
Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.
1997
Asthma
2001 Standout
Expansion of the eukaryotic proteome by alternative splicing
2010 StandoutNature
Effects of Treatment on Airway Inflammation and Thickening of Basement Membrane Reticular Collagen in Asthma: A Quantitative Light and Electron Microscopic Study
1992
Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity
1991
Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma
2014 Standout
Gene expression of the GATA-3 transcription factor is increased in atopic asthma
1999
Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects.
1996
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma
1992
Idiopathic Pulmonary Fibrosis
2001 Standout
Remodeling in Asthma
2009
Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.
1995
Airway Hyperresponsiveness, Increased Intracellular Spaces of Bronchial Epithelium, and Increased Infiltration of Eosinophils and Lymphocytes in Bronchial Mucosa in Asthma
1992
Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines.
1994
Lung immunopathology in cases of sudden asthma death
1997
IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity.
1996
Airway Mucus Function and Dysfunction
2010 Standout
Hox11 paralogous genes are essential for metanephric kidney induction
2002 StandoutNobel
Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
1993
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
1994 StandoutNatureNobel
Intraepithelial Mast Cells in Allergic and Nonallergic Asthma: Assessment Using Bronchial Brushings
1993
Airway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents
1994
Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1.
1997
Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy.
1995
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
Eosinophils: Biology and Role in Disease
1995
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Immunological Aspects of Allergic Asthma
1994
Inhibitory Effect of the TRFK-5 Anti-IL-5 Antibody in a Guinea Pig Model of Asthma
1993
Oligonucleotide therapy of allergic asthma☆☆☆
1999
Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.
1996
A mouse model for the delta F508 allele of cystic fibrosis.
1995 StandoutNobel
Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study
1996
Hox genes in vertebrate development
1994 Standout
Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma
1993
Modulation by interleukin-4 of cytokine release from mononuclear phagocytes in asthma
1994
Allergen exposure induces the activation of allergen‐specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
1993
The Structure of Large and Small Airways in Nonfatal and Fatal Asthma
1993
Increased interleukin-10 messenger RNA expression in atopic allergy and asthma.
1996
The potential role of tumour necrosis factor a in asthma
1993
Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene
1997
Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma
1995
Eosinophil survival activity identified as interleukin-5 is associated with eosinophil recruitment and degranulation and lung injury twenty-four hours after segmental antigen lung challenge
1993
Effect of murine recombinant interleukin‐5 on bronchial reactivity in guinea‐pigs
1993
Sonic hedgehog mediates the polarizing activity of the ZPA
1993 Standout
Molecular basis for selective eosinophil trafficking in asthma: A multistep paradigm☆☆☆
1999
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Sudden-Onset Fatal Asthma: A Distinct Entity with Few Eosinophils and Relatively More Neutrophils in the Airway Submucosa?
1993
Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma
1992 Standout
Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma
1993
The role of T lymphocytes in the pathogenesis of asthma
2003
Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma.
1994
HoxGroup 3 Paralogs Regulate the Development and Migration of the Thymus, Thyroid, and Parathyroid Glands
1998 StandoutNobel
sVCAM-1 levels after segmental antigen challenge correlate with eosinophil influx, IL-4 and IL-5 production, and the late phase response.
1995
Mast Cell and Basophil Number in the Airway Correlate with the Bronchial Responsiveness of Asthmatics
1995
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Asthma
2000 Standout
Airway Inflammation in Mild Intermittent and in Persistent Asthma
1998
Mechanisms of Eosinophil Recruitment
1993
Selective Regulation of Expression of Surface Adhesion Molecules Mac-1, L-selectin, and VLA-4 on Human Eosinophils and Neutrophils
1993
Effect of Inhaled Interleukin-5 on Airway Hyperreactivity and Eosinophilia in Asthmatics
1998
Airway Inflammation in Occupational Asthma
1994
T-Cell-mediated Induction of Airway Hyperreactivity in Mice
1991
Inflammation and Airway Function in Asthma
1998
Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway
2003
Eotaxin mRNA and Protein Expression in Chronic Sinusitis and Allergen-induced Nasal Responses in Seasonal Allergic Rhinitis
1997
Eosinophil-associated TGF- β 1 mRNA Expression and Airways Fibrosis in Bronchial Asthma
1997
CD34 + /Interleukin-5R α Messenger RNA + Cells in the Bronchial Mucosa in Asthma: Potential Airway Eosinophil Progenitors
1999
Cytokines as Mediators of Chronic Asthma
1994
Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics
1993
Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products.
1995
c-fos Proto-oncogene Expression in Bronchial Biopsies of Asthmatics
1992
Dissociation between Airway Inflammation and Airway Hyperresponsiveness in Allergic Asthma
1998
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Release of RANTES, MIP-1 α , and MCP-1 into Asthmatic Airways Following Endobronchial Allergen Challenge
1997
Inflammatory Cell Distribution within and along Asthmatic Airways
1998
Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo.
1995
The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway
1997
The effect of inhaled sodium cromoglycate on cellular infiltration into the bronchial mucosa and the expression of adhesion molecules in asthmatics
1997
Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments
1993
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.
1995 StandoutNobel
Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma
1997
Mouse Eotaxin Expression Parallels Eosinophil Accumulation during Lung Allergic Inflammation but It Is Not Restricted to a Th2-Type Response
1996
Role of a Conserved Retinoic Acid Response Element in Rhombomere Restriction of Hoxb-1
1994 Science
Hox10 and Hox11 Genes Are Required to Globally Pattern the Mammalian Skeleton
2003 StandoutScienceNobel
PARALOGOUS HOX GENES: Function and Regulation
1996
An Essential Role of Mast Cells in the Development of Airway Hyperresponsiveness in a Murine Asthma Model
2000
Requirement for IL-13 Independently of IL-4 in Experimental Asthma
1998 StandoutScience
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.
1996 StandoutNobel
Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma.
1995
Increased numbers of dendritic cells in the bronchial mucosa of atopic asthmatic patients: downregulation by inhaled corticosteroids
1996
Anti-inflammatory effects of inhaled beclomethasone dipropionate in nonatopic asthmatics
1996
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.
1996
Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness.
1993
Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1 beta and tumour necrosis factor-alpha.
1992
Hoxa-2 expression in normal and transposed rhombomeres: independent regulation in the neural tube and neural crest
1994
Zebrafish hox Clusters and Vertebrate Genome Evolution
1998 StandoutScience
Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.
1996
Hox genes and the evolution of vertebrate axial morphology
1995
A Novel T Cell-Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently of IL-4 and IL-5
1998
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice.
1995
T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila.
1996
Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy
1999 StandoutNobel
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.
1996 Standout
Th1/Th2 cells
2007
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness
1998
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Airway eosinophilia and expression of interleukin‐5 protein in asthma and in exacerbations of chronic bronchitis
1996
Pathology of asthma
1992
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.
1994
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production
1997
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.
1996
Bronchial biopsies and airway inflammation
1996
Cell matrix interactions in asthma
1997
Airway and lung elastic fibre is not reduced in asthma nor in asthmatics following corticosteroid treatment
1995
Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed.
1995
Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy
1995
Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms.
1996
Hox genes and serial homology
1993 Nature
Altered compartimentalization of transforming growth factor‐β in asthmatic airways
1997
IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS
1999
Works of May Azzawi being referenced
RANTES chemokine expression is related to acute cardiac cellular rejection and infiltration by CD45RO T-lymphocytes and macrophages.
1998
Tumour necrosis factor alpha and the cardiovascular system: its role in cardiac allograft rejection and heart disease
1999
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
1991
Interleukin-5 mRNA in Mucosal Bronchial Biopsies from Asthmatic Subjects
1991
T Lymphocytes and Activated Eosinophils in Airway Mucosa in Fatal Asthma and Cystic Fibrosis
1992
Identification of Activated T Lymphocytes and Eosinophils in Bronchial Biopsies in Stable Atopic Asthma
1990
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness
1991
T Lymphocytes and Eosinophils in Allergen-induced Late-phase Asthmatic Reactions in the Guinea Pig
1990
294 Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: Comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness
1991
Sequence and embryonic expression of the murine Hox-3.5 gene
1992
293 Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
1991