Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
Bacterial Rhodopsin: Evidence for a New Type of Phototrophy in the Sea
2000 StandoutScience
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels
2005
Demonstration by NMR of folding domains in lysozyme
1991 StandoutNatureNobel
Determining minimum energy conformations of polypeptides by dynamic programming
1990
Calculation of Protein Conformation by the Build-up Procedure. Application to Bovine Pancreatic Trypsin Inhibitor Using Limited Simulated Nuclear Magnetic Resonance Data
1988
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
1998 StandoutNature
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Quantitative methods for developing Fc mutants with extended half‐lives
2005
Positional preference of proline in α‐helices
1999
Biased Probability Monte Carlo Conformational Searches and Electrostatic Calculations for Peptides and Proteins
1994
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding
1988
Free Energy Balance in Protein Folding
1995
Conformational study of the Thr-Gly repeat in theDrosophilaclock protein, PERIOD
1995
Engineered Metal-Binding Proteins: Purification to Protein Folding
1991 StandoutScienceNobel
The complexity and accuracy of discrete state models of protein structure
1995 StandoutNobel
An algorithm for determining the conformation of polypeptide segments in proteins by systematic search
1986
Folding of immunogenic peptide fragments of proteins in water solution
1988
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
FcRn mediates elongated serum half-life of human IgG in cattle
2006
Protein folding in the cell
1992 StandoutNature
Molecular dynamics simulations of the unfolding of an .alpha.-helical analog of ribonuclease A S-peptide in water
1991
Development and testing of a general amber force field
2004 Standout
Conformations of immunoglobulin hypervariable regions
1989 StandoutNatureNobel
Structure and function of immunoglobulins
2010
Medical therapy for ulcerative colitis 2004
2004
A protein-folding reaction under kinetic control
1992 StandoutNatureNobel
The immunologic basis for the treatment of psoriasis with new biologic agents
2002
The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy
2015
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
2010 Standout
Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn)
2006
A molecular dynamics simulation of polyalanine: An analysis of equilibrium motions and helix–coil transitions
1991
Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase
1994 StandoutScience
FcRn: the neonatal Fc receptor comes of age
2007 Standout
The effect of the L ‐azetidine‐2‐carboxylic acid residue on protein conformation. I. Conformations of the residue and of dipeptides
1990
The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure
1989 Standout
Small Libraries of Protein Fragments Model Native Protein Structures Accurately
2002 StandoutNobel
Calculation of conformational ensembles from potentials of mena force
1990
Infliximab for Induction and Maintenance Therapy for Ulcerative Colitis
2005 Standout
Development of the multiple sequence approximation within the AGADIR model of α-helix formation: Comparison with Zimm-Bragg and Lifson-Roig formalisms
1997
Folding of immunogenic peptide fragments of proteins in water solution
1988
Protein structure determination in solution by NMR spectroscopy.
1990 StandoutNobel
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids
1996 Standout
Near-native structure refinement using in vacuo energy minimization
2007 StandoutNobel
A model of the molten globule state from molecular dynamics simulations.
1992 StandoutNobel
Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments
2005
Electrostatics and dynamics of proteins
2003
Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies
2006
Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics simulations with an explicit solvent and an implicit solvent continuum model.
1998
The MM3 force field for amides, polypeptides and proteins
1991
Monte Carlo-minimization approach to the multiple-minima problem in protein folding.
1987
Toward High-Resolution de Novo Structure Prediction for Small Proteins
2005 StandoutScienceNobel
Protein folding
1991 StandoutNobel
New optimization method for conformational energy calculations on polypeptides: Conformational space annealing
1997
Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics simulations with an explicit solvent and an implicit solvent continuum model
1998
A Thermodynamic Scale for the Helix-Forming Tendencies of the Commonly Occurring Amino Acids
1990 Science
Formation of local structures in protein folding
1989
Classical Electrostatics in Biology and Chemistry
1995 StandoutScience
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Molecular coevolution within a Drosophila clock gene
1998 StandoutNobel
Funnel sculpting for in silico assembly of secondary structure elements of proteins
2003 StandoutNobel
The intrinsic helix-forming tendency of L-alanine.
1992
Complete 15 N and 1 H NMR assignments for the amino-terminal domain of the phage 434 repressor in the urea-unfolded form
1992 StandoutNobel
Protein Design, a Minimalist Approach
1989 Science
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
An Engineered Human IgG1 Antibody with Longer Serum Half-Life
2006
Rejection Control and Sequential Importance Sampling
1998
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
2006
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
A Combined Experimental−Computational Investigation of Carbon Dioxide Capture in a Series of Isoreticular Zeolitic Imidazolate Frameworks
2010 StandoutNobel
Structure and mechanism of the reversible photoswitch of a fluorescent protein
2005 StandoutNobel
The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins
1988 StandoutScience
Sequential Monte Carlo Methods for Dynamic Systems
1998 Standout
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Quantum Mechanical Continuum Solvation Models
2005 Standout
Protein topology and stability define the space of allowed sequences
2002 StandoutNobel
A Chemical Approach to Protein Design—Template‐Assembled Synthetic Proteins (TASP)
1989
A study of the biological receptor activator of nuclear factor-kappaB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer.
2006
The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin
1988 Standout
Ribosomal Synthesis of Unnatural Peptides
2005 StandoutNobel
Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design.
1987
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
2.1 and 1.8 Å Average Cα RMSD Structure Predictions on Two Small Proteins, HP-36 and S15
2001 StandoutNobel
Molecular Self-Assembly and Nanochemistry: a Chemical Strategy for the Synthesis of Nanostructures
1991 StandoutScience
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
A lattice model for protein structure prediction at low resolution.
1992 StandoutNobel
Sequential Monte Carlo Methods for Dynamic Systems
1998 Standout
Works of Max Vásquez being referenced
Humanization and characterization of the anti-HLA-DR antibody 1D10
2001
Engineered Human IgG Antibodies with Longer Serum Half-lives in Primates
2004
Finite-difference solution of the Poisson-Boltzmann equation: Complete elimination of self-energy
1996 StandoutNobel
HuM291, A HUMANIZED ANTI-CD3 ANTIBODY, IS IMMUNOSUPPRESSIVE TO T CELLS WHILE EXHIBITING REDUCED MITOGENICITY IN VITRO1
1999
Use of buildup and energy‐minimization procedures to compute low‐energy structures of the backbone of enkephalin
1985
Computed conformational states of the 20 naturally occurring amino acid residues and of the prototype residue α-aminobutyric acid
1983
Helix–coil transition theory including long‐range electrostatic interactions: Application to globular proteins
1987
Effect of sequence‐specific interactions on the stability of helical conformations in polypeptides
1988
Correlation between computed conformational properties of cytochrome c peptides and their antigenicity in a T‐lymphocyte proliferation assay
1987
Finite‐difference solution of the Poisson–Boltzmann equation: Complete elimination of self‐energy
1996 StandoutNobel