Citation Impact
Citing Papers
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
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Rapid and reversible changes in intrahippocampal connectivity during the course of hibernation in European hamsters
2006
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
2015
Roles of tau protein in health and disease
2017
Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins
2017
Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment
2016
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
2014
Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
2014
Tau Isoform Composition Influences Rate and Extent of Filament Formation
2012
Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation
2015
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2012
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2002
Function of tau protein in adult newborn neurons
2009
Nitric oxide induces tau hyperphosphorylation via glycogen synthase kinase‐3β activation
2005
A decade of modeling Alzheimer's disease in transgenic mice
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2010
O-GlcNAc Modification of tau Directly Inhibits Its Aggregation without Perturbing the Conformational Properties of tau Monomers
2014
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
2007 Standout
Clinical Validity of Aß-Protein Deposition Staging in Brain Aging and Alzheimer Disease
2001
Increased p27, an essential component of cell cycle control, in Alzheimer's disease
2003
Evaluating triggers and enhancers of tau fibrillization
2005
Different distribution of phosphorylated tau protein isoforms in Alzheimer's and Pick's diseases
1997
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation
2002
Electron flow through metalloproteins
2010
Are there roles for brain cell senescence in aging and neurodegenerative disorders?
2014
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
2003 Nature
Extracellular phosphorylation of the amyloid β‐peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease
2011
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
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Analysis of the mouse proteome. (I) Brain proteins: Separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation
1999
Genetic analysis of the mouse brain proteome
2002
The contribution of the study of neurodegenerative disorders to the understanding of human memory
2004
Tau phosphorylation and aggregation in Alzheimer's disease pathology
2006
Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation
2012
The Potential for β-Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
2008
Accumulation of flotillin‐1 in tangle‐bearing neurones of Alzheimer's disease
2003
Are Tangles as Toxic as They Look?
2011
Disease-related Modifications in Tau Affect the Interaction between Fyn and Tau
2005
Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model
2010
Cell division in the CNS: Protective response or lethal event in post-mitotic neurons?
2006
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
2015
Accumulation of Filamentous Tau in the Cerebral Cortex of Human Tau R406W Transgenic Mice
2005
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins
2004
Sequence of Aβ-Protein Deposition in the Human Medial Temporal Lobe
2000
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
2007 Standout
Tyrosine Phosphorylation of the β-Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc
2002
Tau in physiology and pathology
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Nitric Oxide and Peroxynitrite in Health and Disease
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Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
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Age-Dependent Neurofibrillary Tangle Formation, Neuron Loss, and Memory Impairment in a Mouse Model of Human Tauopathy (P301L)
2005
Caspase activation precedes and leads to tangles
2010 Nature
Multimodal microtubule binding by the Ndc80 kinetochore complex
2012
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
2006 Standout
Downregulation of Protein Phosphatase 2A Carboxyl Methylation and Methyltransferase May Contribute to Alzheimer Disease Pathogenesis
2004
Rapamycin Attenuates the Progression of Tau Pathology in P301S Tau Transgenic Mice
2013
Glial and neuronal control of brain blood flow
2010 StandoutNature
Alzheimer's Disease-Like Tau Neuropathology Leads to Memory Deficits and Loss of Functional Synapses in a Novel Mutated Tau Transgenic Mouse without Any Motor Deficits
2006
Autophagy in Human Health and Disease
2013 Standout
Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
2008 StandoutNobel
Aberrant expression of NOS isoforms in Alzheimer’s disease is structurally related to nitrotyrosine formation
2002
A Conformation‐ and Phosphorylation‐Dependent Antibody Recognizing the Paired Helical Filaments of Alzheimer's Disease
1997
Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
2011
MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy
2011
Oxidative Stress in Neurodegenerative Diseases
2015
The propagation of prion-like protein inclusions in neurodegenerative diseases
2010
Normal and Pathological Tau Proteins as Factors for Microtubule Assembly
1997
Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus
2013
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Alzheimer's Disease
2010 Standout
Major Depressive Disorder
2008 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Amyloid‐β oligomers induce synaptic damage via Tau‐dependent microtubule severing by TTLL6 and spastin
2013
In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
2008
Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis
2008
The Amyloid State of Proteins in Human Diseases
2012 Standout
Interaction of tau protein with the dynactin complex
2007
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
2012
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.
2000 Standout
Identification of okadaic acid-induced phosphorylation events by a mass spectrometry approach
2006
Isoforms changes of tau protein during development in various species
2003
Tau protein and the neurofibrillary pathology of Alzheimer's disease
1993
A Decade of Tau Transgenic Animal Models and Beyond
2007
Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models
2011
Induction of Inflammatory Mediators and Microglial Activation in Mice Transgenic for Mutant Human P301S Tau Protein
2004
Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau
2012
Aβ-Induced Vascular Oxidative Stress and Attenuation of Functional Hyperemia in Mouse Somatosensory Cortex
2004
Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease
2004
Transmission and spreading of tauopathy in transgenic mouse brain
2009
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
2005
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis
2005
Reassessment of Exosome Composition
2019 Standout
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
2010
The molecular neurobiology of depression
2008 StandoutNature
Proteomics to study genes and genomes
2000 StandoutNature
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Frailty in elderly people
2013 Standout
ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by β-Adrenergic Receptors
1999 StandoutNobel
Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice
2007
Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer’s disease
2014
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Tau Kinetics in Neurons and the Human Central Nervous System
2018
Neuronal and Vascular Oxidative Stress in Alzheimers Disease
2011
Aneuploidy and DNA Replication in the Normal Human Brain and Alzheimer's Disease
2007
Post-translational modifications of tau protein: Implications for Alzheimer's disease
2011
Essential role of tau phosphorylation in adult hippocampal neurogenesis
2009
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
Abortive oncogeny and cell cycle-mediated events in Alzheimer disease
2000
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5
2000
Regional Selective Neuronal Degeneration after Protein Phosphatase Inhibition in Hippocampal Slice Cultures: Evidence for a MAP Kinase-Dependent Mechanism
1998
Tau-Targeted Multifunctional Nanocomposite for Combinational Therapy of Alzheimer’s Disease
2018
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Neuronal Cell Death Is Preceded by Cell Cycle Events at All Stages of Alzheimer's Disease
2003
A Century of Alzheimer's Disease
2006 StandoutScience
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degenerationin vivo
2005
Mutations causing neurodegenerative tauopathies
2004
DNA Synthesis and Neuronal Apoptosis Caused by Familial Alzheimer Disease Mutants of the Amyloid Precursor Protein Are Mediated by the p21 Activated Kinase PAK3
2003
Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Tau Isoform with Three Microtubule Binding Domains is a Marker of New Axons Generated from the Subgranular Zone in the Hippocampal Dentate Gyrus: Implications for Alzheimer's Disease
2012
Mass spectrometry-based proteomics
2003 StandoutNature
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
2013
Intra- and Interspecific Variation in Primate Gene Expression Patterns
2002 StandoutScienceNobel
Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease
2010
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Hierarchical Phosphorylation of Recombinant Tau by the Paired‐Helical Filament‐Associated Protein Kinase Is Dependent on Cyclic AMP‐Dependent Protein Kinase
1999
The β-Propensity of Tau Determines Aggregation and Synaptic Loss in Inducible Mouse Models of Tauopathy
2007
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
2014
Redox cycling and kinetic analysis of single molecules of solution-phase nitrite reductase
2011 StandoutNobel
Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process
2010
Shedding light on tau protein aggregation: the progress in developing highly selective fluorophores
2018
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Ineffective phagocytosis of amyloid-β by macrophages of Alzheimer's disease patients
2005
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
1996 StandoutNature
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
2002 Standout
Resolution of inflammation is altered in Alzheimer's disease
2014
The Development of Amyloid β Protein Deposits in the Aged Brain
2006
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
2019 Standout
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
2001 StandoutScience
Works of Max Holzer being referenced
A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
2010
Analysis of Tau Phosphorylation and Truncation in a Mouse Model of Human Tauopathy
2007
Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease
1998
Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A
1995
Pseudophosphorylation of tau protein alters its ability for self‐aggregation
2004
Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders
1999
Cell-Cycle Markers in a Transgenic Mouse Model of Human Tauopathy
2006
Dephosphorylation of Tau Protein by Calcineurin Triturated into Neural Living Cells
2002
Phosphorylation of Tau, Aβ-Formation, and Apoptosis After In Vivo Inhibition of PP-1 and PP-2A
1998
Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
2012
Alzheimer-Related τ-Pathology in the Perforant Path Target Zone and in the Hippocampal Stratum Oriens and Radiatum Correlates with Onset and Degree of Dementia
2000
Progression of neurofibrillary changes and PHF-τ in end-stage Alzheimer’s disease is different from plaque and cortical microglial pathology
1998
Induction of p21ras in Alzheimer pathology
1995
Aberrancies in signal transduction and cell cycle related events in Alzheimer’s disease
1998
Postmortem changes in the phosphorylation state of tau-protein in the rat brain
1998
Expression of embryonic tau protein isoforms persist during adult neurogenesis in the hippocampus
2006
Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus
2002
Elevated expression of p21ras is an early event in Alzheimer's disease and precedes neurofibrillary degeneration
1999
Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease
1995
Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer’s disease, in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology
2001
Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology
2008
Abnormally phosphorylated tau protein in Alzheimer's disease: Heterogeneity of individual regional distribution and relationship to clinical severity
1994
Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a
2000
Tau and tauopathies
2016
Activated Mitogenic Signaling Induces a Process of Dedifferentiation in Alzheimer's Disease That Eventually Results in Cell Death
2000
Tau gene (MAPT) sequence variation among primates
2004
Abundant Tau Filaments and Nonapoptotic Neurodegeneration in Transgenic Mice Expressing Human P301S Tau Protein
2002
Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimerʼs disease
1996
Distribution of isoforms of the microtubule‐associated protein tau in grey and white matter areas of human brain: A two‐dimensional gelelectrophoretic analysis
1996
Pattern of tau isoforms expression during development in vivo
2009
Reversible Paired Helical Filament-Like Phosphorylation of Tau Is an Adaptive Process Associated with Neuronal Plasticity in Hibernating Animals
2003