Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Digital image processing of intracellular pH in gastric oxyntic and chief cells
1987 StandoutNatureNobel
HLA Expression at the Maternal‐Fetal Interface
1997
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
Protein-tyrosine Phosphatase Inhibitors Block Tumor Necrosis Factor-dependent Activation of the Nuclear Transcription Factor NF-kB
1995
Germ-line transmission of a disrupted β2microglobulin gene produced by homologous recombination in embryonic stem cells
1989 Nature
The Hereditary Hemochromatosis Protein, HFE, Specifically Regulates Transferrin-mediated Iron Uptake in HeLa Cells
1999
Development and Disease in Proteinase-Deficient Mice
1998
Angiogenesis in cancer and other diseases
2000 StandoutNature
Molecular Events Mediating T Cell Activation
1990
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
The cell biology of the insulin receptor
1989
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Central nervous system control of food intake
2000 StandoutNature
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes
1990
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1997 StandoutNature
Adhesion receptors of the immune system
1990 StandoutNature
The Ways of Endocytosis
1989
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
β-adrenoceptors on smooth muscle, nerves and inflammatory cells
1993
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Annexin VI is required for budding of clathrin-coated pits
1992 StandoutNobel
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site
1990 Standout
Ultrastructural evidence for the accumulation of insulin in nuclei of intact 3T3-L1 adipocytes by an insulin-receptor mediated process.
1987
Bacterial lipopolysaccharide priming of P388D1 macrophage-like cells for enhanced arachidonic acid metabolism. Platelet-activating factor receptor activation and regulation of phospholipase A2.
1990
Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.
1982
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Phosphorylation of the small heat-shock protein is regulated by interleukin 1, tumour necrosis factor, growth factors, bradykinin and ATP
1991
Interleukin-1 signal transduction. Increased GTP binding and hydrolysis in membranes of a murine thymoma line (EL4).
1990
Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro
1986
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.
1982
Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro.
1985
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin.
1985
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Differential expression of insulin-like growth factor genes in rat central nervous system.
1988
G alpha 16, a G protein alpha subunit specifically expressed in hematopoietic cells.
1991
Effect of monoclonal antibodies on human insulin receptor autophosphorylation, negative cooperativity, and down-regulation.
1987
Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis
1995 StandoutScience
Mechanisms of regulation of the Na+/H+ exchanger
1986
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.
1983
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.
1993 StandoutNobel
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.
1993
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
1986 StandoutNobel
Class I MHC Molecule-Mediated Inhibition of Sindbis Virus Replication
1999 StandoutNobel
Direct Demonstration of Impaired Functionality of a Purified Desensitized β-Adrenergic Receptor in a Reconstituted System
1984 StandoutScienceNobel
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation.
1992
The major histocompatibility complex class I heavy chain as a structural subunit of the human cell membrane insulin receptor: implications for the range of biological functions of histocompatibility antigens.
1986
Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts
1983 StandoutNatureNobel
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
Insulin and insulin-like growth factors in the CNS
1988
Growth effect of lithium on mouse mammary epithelial cells in serum‐free collagen gel culture
1983
A Receptor-Mediated Pathway for Cholesterol Homeostasis
1986 StandoutScienceNobel
Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals
2002 StandoutNobel
The structure of insulin receptor and its subunits. Evidence for multiple nonreduced forms and a 210,000 possible proreceptor.
1982
Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.
1983 StandoutNobel
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
1983 StandoutNatureNobel
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Epidermal growth factor mimics insulin effects in rat hepatocytes
1986
Functional integrity of desensitized beta-adrenergic receptors.
1983 StandoutNobel
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor
1986
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Mechanisms of Membrane-Receptor Regulation
1984 StandoutNobel
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation.
1987
Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.
1990
High incidence of XXY and XYY males among the offspring of female chimeras from embryonic stem cells.
1995 StandoutNobel
The amiloride-sensitive Na+/H+ exchange system in skeletal muscle cells in culture.
1982
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
1990
Direct demonstration of rapid insulin-like growth factor II Receptor internalization and recycling in rat adipocytes. Insulin stimulates 125I-insulin-like growth factor II degradation by modulating the IGF-II receptor recycling process.
1985
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
1985 StandoutNatureNobel
Insulin receptor desensitization correlates with attenuation of tyrosine kinase activity, but not of receptor endocytosis
1987
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
Epidermal growth factor counteracts the glycogenic effect of insulin in parenchymal hepatocyte cultures
1987
Interleukin-1 represents a new modality for the activation of extracellular signal-regulated kinases/microtubule-associated protein-2 kinases.
1991
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Increased intracellular pH is not necessary for ribosomal protein S6 phosphorylation, increased protein synthesis, or germinal vesicle breakdown in Xenopus oocytes
1985
Human T-Cell Leukemia Virus Type I Tax Activation of NF-ΝB/Rel Involves Phosphorylation and Degradation of IΙBκ and RelA (p65)-Mediated Induction of the italic toc-rel Gene
1994
pH and the recycling of transferrin during receptor-mediated endocytosis.
1983 StandoutNobel
Molecular and biological interaction between major histocompatibility complex class I antigens and luteinizing hormone receptors or beta-adrenergic receptors triggers cellular response in mice.
1988
Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells.
1988 StandoutNobel
Carbachol-activated muscarinic (M1 and M3) receptors transfected into Chinese hamster ovary cells inhibit trafficking of endosomes.
1991 StandoutNobel
Works of Max Fehlmann being referenced
EGF inhibits glucagon stimulation of amino acid transport in primary cultures of adult rat hepatocytes
1981
Activation of human T cells is associated with tyrosine phosphorylation of several cellular proteins
1989
Inhibition and activation of interleukin 2 synthesis by direct modification of guanosine triphosphate-binding proteins.
1988
Regulation of interleukin 2 synthesis by cAMP in human T cells.
1987
A chymotryptic-type serine protease is required for IL-2 production by Jurkat T cells.
1990
Identification of a cellular 110 000-Da protein substrate for the insulin-receptor kinase
1985
Interaction between insulin receptors and major histocompatibility complex antigens in mouse liver membranes
1984
Chymotryptic-type protease inhibitors block the increase in Ca2+ and Il-2 production in activated Jurkat T cells.
1989
Amiloride inhibits protein synthesis in isolated rat hepatocytes
1981
Molecular association between major histocompatibility complex class I antigens and insulin receptors in mouse liver membranes.
1985
α-Fetoprotein stimulates leukotriene synthesis in P388D1 macrophages
1986
Intracellular pathway followed by the insulin receptor covalently coupled to 125I-photoreactive insulin during internalization and recycling.
1986
Immunoprecipitation of insulin receptors by antibodies against Class 1 antigens of the murine H‐2 major histocompatibility complex
1983
Insulin and glucagon stimulation of amino acid transport in isolated rat hepatocytes. Synthesis of a high affinity component of transport.
1979
Internalized insulin receptors are recycled to the cell surface in rat hepatocytes.
1982
Epidermal growth factor stimulates monovalent cation transport in isolated rat hepatocytes
1981
Insulin and glucagon stimulation of (Na+-K+)-ATPase transport activity in isolated rat hepatocytes.
1981
IL-1 signaling for IL-2 production in T cells involves a rise in phosphatidylserine synthesis.
1988
Monoclonal antibody GB36 raised against human trophoblast recognizes a novel epithelial antigen
1987
Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes.
1982
Two types of receptor for insulin-like growth factors in mammalian brain.
1985
Redistribution of 125I-Insulin on the Surface of Rat Hepatocytes as a Function of Dissociation Time
1985
Two different protein kinase activities are associated with the insulin receptor
1983