Standout Papers
Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
2019 StandoutNobel
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Recent advances in our understanding of neurodegeneration
2009
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
The ankyrin repeat as molecular architecture for protein recognition
2004
Coping with stress: multiple ways to activate p53
2007
Chemically Synthesized Ubiquitin Extension Proteins Detect Distinct Catalytic Capacities of Deubiquitinating Enzymes
1999
A De Novo Protein Binding Pair By Computational Design and Directed Evolution
2011 StandoutNobel
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
The role of autophagy in neurodegenerative disease
2013 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Cysteine Promoted C‐Terminal Hydrazinolysis of Native Peptides and Proteins
2013 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
2012
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Genetic Animal Models of Parkinson's Disease
2010
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
2010
Transcriptional regulation by hypoxia inducible factors
2013
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Autophagy: Renovation of Cells and Tissues
2011 Standout
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
Chemical protein synthesis
1998
Exploring the link between glucocerebrosidase mutations and parkinsonism
2011
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
The ubiquitin–proteasome system and cancer
2005
Parkinson's disease
2015 Standout
Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation
2011 StandoutNobel
Autophagy in Human Health and Disease
2013 Standout
Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy
2009
Mechanisms of mitophagy
2010 Standout
Regulation of YAP by Mechanical Strain through Jnk and Hippo Signaling
2014
RNA Cargoes Associating with FMRP Reveal Deficits in Cellular Functioning in Fmr1 Null Mice
2003
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
2015 StandoutNobel
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
Distinct RolesIn Vivofor the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein
2011
Chemistry and Biology of the Ubiquitin Signal
2012
FHL family members suppress vascular endothelial growth factor expression through blockade of dimerization of HIF1α and HIF1β
2012
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
2012
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
2016
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
2006 Standout
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
2014
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53
2005
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
2012
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
2013
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Cucurbituril-Based Molecular Recognition
2015 Standout
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
KEGG: integrating viruses and cellular organisms
2020 Standout
Die Chemie und Biologie des Ubiquitin‐Signals
2012
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)
2009 StandoutNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
The ubiquitin–proteasome system and cancer
2005
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
2015 StandoutNobel
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Neuronal‐specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age‐related cognitive decline
2019
Probing Conformational Changes of Ubiquitin by Host–Guest Chemistry Using Electrospray Ionization Mass Spectrometry
2012
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Targeting Protein–Protein Interactions in the HIF System
2016
Ankyrin Repeat: A Unique Motif Mediating Protein−Protein Interactions
2006
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020
Works of Maureen Mee being referenced
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
2012 StandoutNobel
Is malfunction of the ubiquitin proteasome system the primary cause of α-synucleinopathies and other chronic human neurodegenerative disease?
2008
Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies
2008
Gankyrin Is an Ankyrin-repeat Oncoprotein That Interacts with CDK4 Kinase and the S6 ATPase of the 26 S Proteasome
2002
Synthetic, structural and biological studies of the ubiquitin system: synthesis and crystal structure of an analogue containing unnatural amino acids
1997