Matthew Todd

Computational protein design enables a novel one-carbon assimilation pathway

Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability

Pretreatment of lignocellulose: Formation of inhibitory by-products and strategies for minimizing their effects

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

The effects of oxidative stress on female reproduction: a review

Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate

Gut microbiota functions: metabolism of nutrients and other food components

Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells

In vitro cytotoxicity assays: Comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride

Isobutanol production at elevated temperatures in thermophilic Geobacillus thermoglucosidasius

The isoflavones equol and genistein do not induce xenobiotic-metabolizing enzymes in mouse and in human cells

Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells22Abbreviations: AhR, aryl hydrocarbon receptor; CAT, chloramphenicol acetyl transferase; CYP1A1, cytochrome P450 1A1; FBS, fetal bovine serum; GADD, growth arrest and DNA damage; GRP78, 78-kD glucose-regulated protein; GST, glutathione S-transferase; HMTII, human metallothionein II; HSP, heat shock protein; 3-MC, 3-methylcholanthrene; NF-κBRE, nuclear factor of κ enhancer responsive element; RARE, retinoid acid responsive element; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDF, 2,3,7,8-tetrachlorodibenzofuran; UDS, unscheduled DNA synthesis; and XRE, xenobiotic responsive element.

Molecular Genotoxicity Profiles of Apoptosis-Inducing Vanadocene Complexes

The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors

Alternative Splicing of NURF301 Generates Distinct NURF Chromatin Remodeling Complexes with Altered Modified Histone Binding Specificities

Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations

Bioprocessing of agricultural residues to ethanol utilizing a cellulolytic extremophile

Effects of Arsenic, Cadmium, Chromium, and Lead on Gene Expression Regulated by a Battery of 13 Different Promoters in Recombinant HepG2 Cells

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450

Targeting cancer with small molecule kinase inhibitors

The role of iron and reactive oxygen species in cell death

The biochemistry and medical significance of the flavonoids

Cellular Stress Response Pathway System as a Sentinel Ensemble in Toxicological Screening

Expansion of the eukaryotic proteome by alternative splicing

Next generation biofuel engineering in prokaryotes

The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate

Recent progress in consolidated bioprocessing

A thermostable Cas9 with increased lifetime in human plasma

Exploring the Mechanism Responsible for Cellulase Thermostability by Structure-Guided Recombination

Heavy Metal Toxicity and the Environment

Comprehensive analysis of kinase inhibitor selectivity

Improved lignocellulose conversion to biofuels with thermophilic bacteria and thermostable enzymes

Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation

In-vitro cytotoxic and genotoxic effects of arsenic trioxide on human leukemia (HL-60) cells using the MTT and alkaline single cell gel electrophoresis (Comet) assays

Complete genome sequence, metabolic model construction and phenotypic characterization of Geobacillus LC300, an extremely thermophilic, fast growing, xylose-utilizing bacterium

Metabolic Engineering: Past and Future

Differential Cytotoxicity and Gene Expression in Human Liver Carcinoma (HepG2) Cells Exposed to Arsenic Trioxide, and Monosodium Acid Methanearsonate (MSMA)

Yap5 Is an Iron-Responsive Transcriptional Activator That Regulates Vacuolar Iron Storage in Yeast

Nucleophosmin Sets a Threshold for p53 Response to UV Radiation

Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma cells (HepG2) exposed to cadmium chloride

The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma cells (HepG2)exposed to cadmium chloride

Mercury Induces Cytotoxicity and Transcriptionally Activates Stress Genes in Human Liver Carcinoma (HepG2) Cells

Characterization of novel isoforms and evaluation of SNF2L/SMARCA1 as a candidate gene for X-linked mental retardation in 12 families linked to Xq25-26

Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production

Oligomerization of the Na,K-ATPase in Cell Membranes

Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity

The CAT-Tox (L) Assay: A Sensitive and Specific Measure of Stress-Induced Transcription in Transformed Human Liver Cells