Citation Impact
Citing Papers
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
2003 StandoutNobel
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
1988 StandoutNature
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
1992 Standout
Molecular characterization of a peripheral receptor for cannabinoids
1993 StandoutNature
Overproduction of protein kinase C causesdisordered growth control in rat fibroblasts
1988
Cloning and Expression of a Murine Fascin Homolog from Mouse Brain
1995 StandoutNobel
Chapter 14: Transmitter release: target of regulation by protein kinase C?
1991
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase
1989 StandoutNobel
Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins
1995 StandoutNobel
β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs
2002 StandoutNobel
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
Munc13-1 Is a Presynaptic Phorbol Ester Receptor that Enhances Neurotransmitter Release
1998 StandoutNobel
Molecular themes in oncogenesis
1991 StandoutNobel
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Characterization of the Cysteine-rich Region of the Caenorhabditiselegans Protein Unc-13 as a High Affinity Phorbol Ester Receptor
1995
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.
1986 StandoutNobel
Ca2+-dependent and -independent release of neurotransmitters from PC12 cells: a role for protein kinase C activation?
1984
Phorbol ester- and diacylglycerol-mediated desensitization of cardiac beta-adrenergic receptors.
1985
Protein kinase C phosphorylates pp60src at a novel site
1985
Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes
1987
Perspectives on the Role of Protein Kinase C in Stimulus-Response Coupling<xref ref-type="fn" rid="FN4">4</xref>
1986
Isozymic forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase.
1986
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.
1988
Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.
1987 StandoutNobel
Phorbol esters and beta-adrenergic agonists mediate desensitization of adenylate cyclase in rat glioma C6 cells by distinct mechanisms.
1985
Expression and properties of two distinct classes of the phorbol ester receptor family, four conventional protein kinase C types, and a novel protein kinase C.
1990
Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.
1984
Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase C.
1985
A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family
1988
Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products
1994
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Substrate specificity of protein kinase C
1986
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Cell Signalling Through Phospholipid Metabolism
1986
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
1986 StandoutNobel
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.
1987 StandoutNobel
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.
1984
Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
1986 StandoutNobel
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
1989 StandoutScienceNobel
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane
1984 Nature
Phorbol esters inhibit alpha 1-adrenergic effects and decrease the affinity of liver cell alpha 1-adrenergic receptors for (-)-epinephrine.
1986
The role of protein kinase C in cell surface signal transduction and tumour promotion
1984 StandoutNature
The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression
1987
Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone
1987 StandoutNatureNobel
Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.
1985
Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.
1987
Competitive inhibition by diacylglycerol of specific phorbol ester binding.
1984
Regulation of the epidermal growth factor receptor by phosphorylation
1985
Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence
1985 StandoutNobel
A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans.
1991 StandoutNobel
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.
1991
Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans.
1991 StandoutNobel
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
1987 Standout
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
1987 Standout
Mechanism of cyclic GMP inhibition of inositol phosphate formation in rat aorta segments and cultured bovine aortic smooth muscle cells.
1990 StandoutNobel
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
1987 StandoutNatureNobel
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
1993 StandoutNobel
Photochemically generated cytosolic calcium pulses and their detection by fluo-3
1989 StandoutNobel
Phorbol ester effects on neurotransmission: interaction with neurotransmitters and calcium in smooth muscle.
1985
Thyrotropin-releasing hormone induces redistribution of protein kinase C in GH4C1 rat pituitary cells.
1985
The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor
1986 Science
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
1985 StandoutScience
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
1987 StandoutNatureNobel
A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells.
1986
Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.
1985
Induction of expression and phosphorylation of the human interleukin 2 receptor by a phorbol diester.
1984
Pharmacology of the receptors for the phorbol ester tumor promoters
2000
Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton.
1985
Affinity chromatography of protein kinase C-phorbol ester receptor on polyacrylamide-immobilized phosphatidylserine.
1984
Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.
1990 StandoutNobel
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.
1984
Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.
1985 StandoutNobel
Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium.
1987 StandoutNobel
Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.
1984
Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.
1984
A phorbol ester and A23187 act synergistically to release acetylcholine from the guinea pig ileum
1984
Turnover of Inositol Phospholipids and Signal Transduction
1984 Science
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
1985
Phospholipid Turnover in Hormone Action
1984
The Pathogenesis of Atherosclerosis — An Update
1986 Standout
Autophosphorylation of rat brain Ca2+-activated and phospholipid-dependent protein kinase.
1986
Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding.
1985
Works of Matthew James being referenced
Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol.
1983