Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Design of structurally distinct proteins using strategies inspired by evolution
2016 Science
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli
2014 Science
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Structure of eIF3b RNA Recognition Motif and Its Interaction with eIF3j
2006
Structures of the RNA-guided surveillance complex from a bacterial immune system
2011 StandoutNatureNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
A Complex of Cas Proteins 5, 6, and 7 Is Required for the Biogenesis and Stability of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-derived RNAs (crRNAs) in Haloferax volcanii
2014
Double-stranded Endonuclease Activity in Bacillus halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
2012
Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array
2016
Fragmentation of the CRISPR-Cas Type I-B signature protein Cas8b
2017
Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA
2012 StandoutNobel
Characterization of CRISPR RNA processing in Clostridium thermocellum and Methanococcus maripaludis
2012
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Tuning in to Interference: R-Loops and Cascade Complexes in CRISPR Immunity
2012
CRISPR-based technologies: prokaryotic defense weapons repurposed
2014
Cutting it close: CRISPR-associated endoribonuclease structure and function
2014 StandoutNobel
Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases
2013 StandoutNobel
Comparative analysis of Cas6b processing and CRISPR RNA stability
2013
The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
2013 StandoutNobel
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
RNA Binding-independent Dimerization of Adenosine Deaminases Acting on RNA and Dominant Negative Effects of Nonfunctional Subunits on Dimer Functions
2007
RNA catalyses nuclear pre-mRNA splicing
2013 Nature
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
crRNA and tracrRNA guide Cas9-mediated DNA interference inStreptococcus thermophilus
2013
Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
2017
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Is the spliceosome a ribonucleoprotein enzyme?
2008
DNA Targeting by a Minimal CRISPR RNA-Guided Cascade
2016 StandoutNobel
Affinity purification of T7 RNA transcripts with homogeneous ends using ARiBo and CRISPR tags
2013
Conservation and Variability in the Structure and Function of the Cas5d Endoribonuclease in the CRISPR-Mediated Microbial Immune System
2013
Structure of the Cmr2-Cmr3 Subcomplex of the Cmr RNA Silencing Complex
2013
Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli
2014 Nature
Foreign DNA capture during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis
2013
Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR‐mediated bacterial immunity
2012
The coming of age of de novo protein design
2016 StandoutNatureNobel
Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system
2014
Essential Features and Rational Design of CRISPR RNAs that Function with the Cas RAMP Module Complex to Cleave RNAs
2012
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Unravelling the structural and mechanistic basis of CRISPR–Cas systems
2014
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes
2015 StandoutNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System
2012
Recognition and Cleavage of a Nonstructured CRISPR RNA by Its Processing Endoribonuclease Cas6
2013
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Cascade-mediated binding and bending of negatively supercoiled DNA
2012
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems
2013
Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System
2012 StandoutNobel
Mechanism of substrate selection by a highly specific CRISPR endoribonuclease
2012 StandoutNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity
2015 StandoutNobel
Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system
2016
The impact of CRISPR repeat sequence on structures of a Cas6 protein–RNA complex
2012
Structure of the Cmr2 Subunit of the CRISPR-Cas RNA Silencing Complex
2012
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex
2014
Nucleases: diversity of structure, function and mechanism
2010
Type I-E CRISPR-Cas Systems Discriminate Target from Non-Target DNA through Base Pairing-Independent PAM Recognition
2013
ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8
2008
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures
2017
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
RNA processing enables predictable programming of gene expression
2012 StandoutNobel
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site
2011
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Functions and Regulation of RNA Editing by ADAR Deaminases
2010
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing
2013
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Crystal structure of a CRISPR RNA–guided surveillance complex bound to a ssDNA target
2014 Science
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci
2014
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
CRISPR interference: a structural perspective
2013
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Structure Principles of CRISPR-Cas Surveillance and Effector Complexes
2015
Engineering Translational Activators with CRISPR-Cas System
2015
Active site plasticity enables metal-dependent tuning of Cas5d nuclease activity in CRISPR-Cas type I-C system
2013
CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea
2013
CRYO-ELECTRON MICROSCOPY OF SPLICEOSOMAL COMPONENTS
2006
Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / CRISPR Associated (Cas) Systems
2012
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Rewriting a genome
2013 StandoutNatureNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Works of Matthew J. Schellenberg being referenced
Crystal structure of a core spliceosomal protein interface
2006
Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases
2012
Recognition and maturation of effector RNAs in a CRISPR interference pathway
2011
FRET Analysis of in Vivo Dimerization by RNA-editing Enzymes
2006
Structural elucidation of a PRP8 core domain from the heart of the spliceosome
2008
Context-Dependent Remodeling of Structure in Two Large Protein Fragments
2010
A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation
2013